20250201 20180803 20180425 20250201 IID00596 Cytochrome b-245 light chain Cytochrome b(558) alpha chain Cytochrome b558 subunit alpha Neutrophil cytochrome b 22 kDa polypeptide Superoxide-generating NADPH oxidase light chain subunit p22 phagocyte B-cytochrome p22-phox Homo sapiens 195 P13498 Q14090 Q9BR72 Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. Nucleus. SL-0191 unkown Nucleus speckle. SL-0186 reported 0 0 Phosphothreonine 147 147 Phosphoserine 168 168 CYBA Cytochrome b-245 light chain MGQIEWAMWANEQALASGLILITGGIVATAGRFTQWYFGAYSIVAGVFVCLLEYPRGKRKKGSTMERWGQKYMTAVVKLFGPFTRNYYVRAVLHLLLSVPAGFLLATILGTACLAIASGIYLLAAVRGEQWTPIEPKPRERPQIGGTIKQPPSNPPPRPPAEARKKPSEEEAAVAAGGPPGGPQVNPIPVTDEVV 1 1wlpA 149 168 order 1 4 7yxwD 151 161 order 2 5 7yxwD 162 168 disorder 2 1 1wlp NMR 16326715 K.OGURA,I.NOBUHISA,S.YUZAWA,R.TAKEYA,S.TORIKAI,K.SAIKAWA,H.SUMIMOTO,F.INAGAKI 2006 J.BIOL.CHEM. 281 3660 nmr 1wlp A 149 168 100 0 1 1wlp 7486 Hetero dimer 1wlpA P13498 IID00596 1wlpB P14598 IID00597 1wlpB-1wlpA 2 7yxw X-RAY 277K 7.5 35707140 J.B.GARSI,B.KOMJATI,G.CULLIA,I.FEJES,M.SIPOS,Z.SIPOS,E.FORDOS,P.MARKACZ,B.BALAZS,N.LANCELOT,S.BERGER,E.RAIMBAUD,D.BROWN,L.M.VUILLARD,L.HABERKORN,C.CUKIER,Z.SZLAVIK,S.HANESSIAN 2022 ACS MED.CHEM.LETT. 13 949 x-ray 7yxw D 151 168 100 1 162 168 1 7yxw 7794 Hetero dimer 7yxwD P13498 IID00596 7yxwA P14598 IID00597 7yxwA-7yxwD ProS 1 predicted 1 149 164 This region is predicted to be disordered by AlphaFold and NeProc; The residues from Lys149 to Arg164 of p22phox-(149-168) form a relatively well defined structure, although the C-terminal four residues (165-168) are disordered (PMID: 16326715). ProS 2 predicted 4 151 161 This region is predicted to be disordered by AlphaFold and NeProc.

P13498-1 CYBA/NCF1

3-59,62-134,155-158 1-2,60-61,135-154,159-195 1-134 135-195 145-150,182-195 151-183