20250201 20180803 20180228 20250201 IID50088 Histone deacetylase complex subunit SAP25 25 kDa Sin3-associated polypeptide Sin3 corepressor complex subunit SAP25 mSin3A-binding protein Mus musculus 186 Q1EHW4 Involved in the transcriptional repression mediated by the mSIN3A but not the N-CoR corepressor complex. 0 0 0 0 Sap25 Histone deacetylase complex subu MSPLPLRDPSHQANAGPRLVEPSCGPGVSLSNRTLCHPSWPMYDNWGRSPTTSERPEEEQVVSKDTGVPVRNYEDVFLLDPLLPCGQRVPLILTKPPQQAMDSRKLLLPPPIMSPSVHPSSSQACSSTWLSEAEMIALAGLLQMSQGEQTPNCVASSLPSTSCPDPVSVSEDPGPSGDQSCSGTDT 1 2rmsB 126 186 order 1 2 126 186 disorder 2 3 2rmsB 126 127 high_rmsd 1 4 2rmsB 147 186 high_rmsd 1 1 2rms NMR 18089292 S.C.SAHU,K.A.SWANSON,R.S.KANG,K.HUANG,K.BRUBAKER,K.RATCLIFF,I.RADHAKRISHNAN CONSERVED THEMES IN TARGET RECOGNITION BY THE PAH1 AND PAH2 DOMAINS OF THE SIN3 TRANSCRIPTIONAL COREPRESSOR 2007 J.MOL.BIOL. 375 1444 nmr 2rms B 126 186 100 0 1 2rms 6920 Hetero dimer 2rmsB Q1EHW4 IID50088 2rmsA Q60520 IID50089 2rmsA-2rmsB 2 NMR 18089292 S.C.SAHU,K.A.SWANSON,R.S.KANG,K.HUANG,K.BRUBAKER,K.RATCLIFF,I.RADHAKRISHNAN CONSERVED THEMES IN TARGET RECOGNITION BY THE PAH1AND PAH2 DOMAINS OF THE SIN3 TRANSCRIPTIONALCOREPRESSOR 2007 J.MOL.BIOL. 375 1444 ProS 1 verified 1 132 145 2 126 186
Q1EHW4-1 Sap25/Sin3a Solution structure of the mSin3A PAH1-SAP25 SID complex
76-92,94-94,107-114,116-119,129-146 1-75,93-93,95-106,115-115,120-128,147-186 34-37,44-47,66-113 1-33,38-43,48-65,114-186 5-33,38-43,114-119,126-146,175-186