20250201 20180803 20180228 20250201 IID50120 P-selectin glycoprotein ligand 1 Selectin P ligand Mus musculus 397 Q62170 A SLe(x)-type proteoglycan, which through high affinity, calcium-dependent interactions with E- and P-selectins, mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation. Critical for the initial leukocyte capture. 0 0 Sulfotyrosine 54 54 Phosphothreonine 391 391 Phosphoserine 394 394 Selplg P-selectin glycoprotein ligand 1 MSPSFLVLLTILGPGNSLQLQDPWGHETKEAPGPVHLRERRQVVGDDDFEDPDYTYNTDPPELLKNVTNTVAAHPELPTTVVMLERDSTSAGTSERATEKIATTDPTAPGTGGTAVGMLSTDSATQWSLTSVETVQPASTEVETSQPAPMEAETSQPAPMEAETSQPAPMEAETSQPAPMEADTSQPAPMEAETSQPAPNEAETSKPAPTEAETSKPAPTEAETTQLPRIQAVKTLFTTSAATEVPSTEPTTMETASTESNESTIFLGPSVTHLPDSGLKKGLIVTPGNSPAPTLPGSSDLIPVKQCLLIILILASLATIFLVCTVVLAVRLSRKTHMYPVRNYSPTEMICISSLLPEGGDGAPVTANGGLPKVQDLKTEPSGDRDGDDLTLHSFLP 1 2emtC 331 346 order 1 2 2emtC 347 348 disorder 1 3 2emtD 331 347 order 1 4 2emtD 348 348 disorder 1 5 2emtE 331 334 disorder 1 6 2emtE 335 343 order 1 7 2emtE 344 348 disorder 1 1 2emt X-RAY 277K 8.2 18076570 Y.TAKAI,K.KITANO,S.TERAWAKI,R.MAESAKI,T.HAKOSHIMA STRUCTURAL BASIS OF PSGL-1 BINDING TO ERM PROTEINS 2007 GENES CELLS 12 1329 x-ray 2emt C 331 348 100 1 347 348 x-ray 2emt D 331 348 100 1 348 348 x-ray 2emt E 331 348 100 2 331 334 344 348 1 2emt_1 3189 Hetero dimer 2emtA P26043 IID50114 2emtC Q62170 IID50120 2emtE Q62170 IID50120 2emtE-2emtA 2emtC-2emtA 2 2emt_2 3190 Hetero dimer 2emtB P26043 IID50114 2emtD Q62170 IID50120 2emtD-2emtB
Q62170-1 Selplg/Rdx Crystal Structure Analysis of the radixin FERM domain complexed with adhesion molecule PSGL-1
2-11,13-13,303-335,348-357 1-1,12-12,14-302,336-347,358-397 1-39,304-360 40-303,361-397 40-60,374-379,384-397 102-115,308-322