<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<sbgn xmlns="http://sbgn.org/libsbgn/0.2">
  <map language="process description">
    <extension>
      <selfEntry uniprot="O15350" iid="IID00753"/>
      <renderInformation id="renderInformation" program-name="sbgnviz" program-version="6.0.2" background-color="#00000000">
        <listOfColorDefinitions>
          <colorDefinition id="color_transparence" value="#ffffffff"/>
          <colorDefinition id="color_stroke" value="#555555"/>
          <colorDefinition id="color_white" value="#ffffff"/>
          <colorDefinition id="color_red" value="#ff0000"/>
          <colorDefinition id="color_association" value="#707070ff"/>
          <colorDefinition id="color_dissociation" value="#ffffff"/>
          <colorDefinition id="color_location" value="#e7effaff"/>
          <colorDefinition id="color_phenotype" value="#e7effaff"/>
          <colorDefinition id="color_complex" value="#e7effaff"/>
        </listOfColorDefinitions>
        <listOfStyles>
          <style id="macromolecule" idList="0 Node1 Node2 Node4 Node5 Node3 Node6 Node8">
            <g stroke="color_stroke" stroke-width="1.25" fill="color_transparence" font-size="11" font-family="monospace" font-weight="normal" font-style="normal" font-color="#000" background-image-opacity="1" background-opacity="1"/>
          </style>
          <style id="state_variable" idList="0 Node7">
            <g stroke="color_stroke" stroke-width="1" fill="color_white" font-size="9" font-family="monospace" font-weight="normal" font-style="normal" font-color="#0f0f0f"/>
          </style>
          <style id="prop_phenotype" idList="0 Node9">
            <g stroke="color_stroke" stroke-width="1.25" fill="color_phenotype" font-size="11" font-family="monospace" font-weight="normal" font-style="normal" font-color="#000" background-image-opacity="1" background-opacity="1"/>
          </style>
          <style id="edge" idList="0 Node6-Node9 Node1-Node10.1 Node2-Node10 Node10.2-Node3">
            <g stroke="color_stroke" stroke-width="1.25"/>
          </style>
          <style id="process" idList="0 Node10">
            <g stroke="color_stroke" stroke-width="1.25" fill="color_transparence" background-image-opacity="1" background-opacity="1"/>
          </style>
        </listOfStyles>
      </renderInformation>
      <mapProperties>
        <compoundPadding>0</compoundPadding>
        <extraCompartmentPadding>14</extraCompartmentPadding>
        <extraComplexPadding>10</extraComplexPadding>
        <arrowScale>1.25</arrowScale>
        <showComplexName>true</showComplexName>
        <dynamicLabelSize>regular</dynamicLabelSize>
        <inferNestingOnLoad>false</inferNestingOnLoad>
        <fitLabelsToNodes>false</fitLabelsToNodes>
        <fitLabelsToInfoboxes>false</fitLabelsToInfoboxes>
        <recalculateLayoutOnComplexityManagement>true</recalculateLayoutOnComplexityManagement>
        <rearrangeOnComplexityManagement>true</rearrangeOnComplexityManagement>
        <animateOnDrawingChanges>true</animateOnDrawingChanges>
        <adjustNodeLabelFontSizeAutomatically>false</adjustNodeLabelFontSizeAutomatically>
        <enablePorts>true</enablePorts>
        <enableSIFTopologyGrouping>false</enableSIFTopologyGrouping>
        <allowCompoundNodeResize>true</allowCompoundNodeResize>
        <mapColorScheme>black_white</mapColorScheme>
        <mapColorSchemeStyle>solid</mapColorSchemeStyle>
        <mapName>Pathway #8</mapName>
        <highlightColor>#0B9BCD</highlightColor>
        <extraHighlightThickness>2</extraHighlightThickness>
      </mapProperties>
      <popperInfo>
        <glyph id="Node4">
          <entry uniprot="Q00987" iid="IID00163"/>
          <pdb pdb_id="2mpsA"/>
          <complex gene="TP73" iid1="IID00163" iid2="IID00753" cluster="3902"/>
        </glyph>
        <glyph id="Node5">
          <entry uniprot="O15350" iid="IID00753"/>
          <pdb pdb_id="2mpsB"/>
          <complex gene="MDM2" iid1="IID00753" iid2="IID00163" cluster="3902"/>
        </glyph>
        <glyph id="Node6">
          <entry uniprot="O15350" iid="IID00753"/>
        </glyph>
        <glyph id="Node8">
          <entry uniprot="Q00987" iid="IID00163"/>
        </glyph>
        <arc id="Node1-Node10.1">
          <process process_no="1"/>
        </arc>
        <arc id="Node2-Node10">
          <process process_no="1"/>
        </arc>
        <arc id="Node10.2-Node3">
          <process process_no="1"/>
        </arc>
      </popperInfo>
      <isEdited>true</isEdited>
    </extension>
    <glyph id="Node9" class="phenotype" obj_id="3">
      <label text="&#xA;&#xA;&#xA;&#xA;&#xA;&#xA;&#xA;&#xA;loss of&#xA;interaction with&#xA;EP300 and CBP&#xA;&#xA;"/>
      <bbox x="341.88481943340736" y="9.553410162843544" w="144" h="30"/>
    </glyph>
    <glyph id="Node1" class="complex" obj_id="1 2">
      <bbox x="-6.128273541833423" y="-5.420130941673335" w="0" h="0"/>
      <glyph id="Node2" class="complex" obj_id="1 2">
        <bbox x="0.49672645816657734" y="46.75" w="0" h="0"/>
        <glyph id="Node4" class="macromolecule" obj_id="1 2">
          <label text="MDM2"/>
          <bbox x="7.121726458166577" y="53.375" w="90" h="30"/>
        </glyph>
      </glyph>
      <glyph id="Node5" class="macromolecule" obj_id="1">
        <label text="TP73"/>
        <bbox x="6.722381166533282" y="1.2048690583266684" w="90" h="30"/>
      </glyph>
    </glyph>
    <glyph id="Node3" class="complex" obj_id="3">
      <bbox x="194.60883737085754" y="-9.06105396225648" w="0" h="0"/>
      <glyph id="Node6" class="macromolecule" obj_id="3">
        <label text="TP73"/>
        <bbox x="201.23383737085754" y="-2.436053962256487" w="90" h="30"/>
        <glyph id="Node7" class="state variable">
          <state value="mUb"/>
          <bbox x="0" y="0" w="12" h="12"/>
        </glyph>
      </glyph>
      <glyph id="Node8" class="macromolecule" obj_id="3">
        <label text="MDM2"/>
        <bbox x="201.77377190002085" y="51.9395182372631" w="90" h="30"/>
      </glyph>
    </glyph>
    <glyph id="Node10" class="process">
      <bbox x="141.04676282600175" y="29.21183634567761" w="15" h="15"/>
      <port id="Node10.1" x="150.17176282600175" y="38.33683634567761"/>
      <port id="Node10.2" x="150.17176282600175" y="38.33683634567761"/>
    </glyph>
    <arc id="Node6-Node9" class="modulation" source="Node6" target="Node9">
      <start x="0" y="0"/>
      <end x="0" y="0"/>
    </arc>
    <arc id="Node1-Node10.1" class="consumption" source="Node1" target="Node10.1">
      <start x="0" y="0"/>
      <end x="0" y="0"/>
    </arc>
    <arc id="Node2-Node10" class="catalysis" source="Node2" target="Node10">
      <start x="0" y="0"/>
      <end x="0" y="0"/>
    </arc>
    <arc id="Node10.2-Node3" class="production" source="Node10.2" target="Node3">
      <start x="0" y="0"/>
      <end x="0" y="0"/>
    </arc>
  </map>
  <formatOutput>1</formatOutput>
</sbgn>
