1.0.0 O43524-1 1 1 1 nucleus FALSE FOXO3 1 O43524 IID00433 FALSE 2 1 1 EC:2.7.11.1 FALSE AKT1(Ps) 1 P31749 IID00412 FALSE Phosphorylations 1 3 1 1 FALSE FOXO3(Ps) 1 O43524 IID00433 FALSE Phosphorylations 1 32 32 2 253 253 3 315 315 4 1 1 FALSE FOXO3(Ps) 1 O43524 IID00433 FALSE Phosphorylations 1 32 32 2 253 253 3 315 315 2 1 14-3-3 epsilion FALSE YWHAE 1 P62258 IID00512 FALSE 5 1 1 FALSE FOXO3(Ps) 1 O43524 IID00433 FALSE 7v9bB Phosphorylations 1 32 32 2 253 253 3 315 315 YWHAE 1 P62258 IID00512 FALSE 7v9bA 6 1 1 FALSE CSNK1A1 1 P48729 FALSE 7 1 1 FALSE FOXO3(Ps) 1 O43524 IID00433 FALSE Phosphorylations 1 32 32 2 253 253 3 315 315 4 318 318 5 321 321 YWHAE 1 P62258 IID00512 FALSE 8 1 1 FALSE FOXO3(Ps) 1 O43524 IID00433 FALSE Phosphorylations 1 32 32 2 253 253 3 315 315 4 318 318 5 321 321 YWHAE 1 P62258 IID00512 FALSE 2 1 FALSE E2 FALSE SCF_complex SKP2/SKP1/CUL1/RBX1 FALSE 9 1 1 FALSE FOXO3(Ps) 1 O43524 IID00433 FALSE Phosphorylations 1 32 32 2 253 253 3 315 315 4 318 318 5 321 321 YWHAE 1 P62258 IID00512 FALSE E2 FALSE SCF_complex FALSE 10 1 1 FALSE E2 FALSE SCF_complex FALSE 11 1 1 FALSE FOXO3(Ps,Ub) 1 O43524 IID00433 proteolysis FALSE Phosphorylations 1 32 32 2 253 253 3 315 315 4 318 318 5 321 321 Ubiquitination 1 YWHAE 1 P62258 IID00512 FALSE E2 FALSE SCF_complex FALSE 12 1 1 FALSE PPP2CA 1 P67775 IID00958 FALSE 13 1 1 FALSE FOXO3 1 O43524 IID00433 FALSE YWHAE 1 P62258 IID00512 FALSE 14 1 1 FALSE FOXO3 1 O43524 IID00433 FALSE 2 1 FALSE YWHAE 1 P62258 IID00512 FALSE 15 1 1 FALSE MAPK1 1 P28482 FALSE 2 FALSE MAPK3 1 P27361 FALSE 16 1 1 FALSE FOXO3(Ps) 1 O43524 IID00433 FALSE Phosphorylations 1 294 294 2 344 344 3 425 425 17 1 1 FALSE MDM2 1 Q00987 IID00163 FALSE 18 1 1 proteolysis FALSE FOXO3(Ps,Ub) 1 O43524 IID00433 FALSE Phosphorylations 1 294 294 2 344 344 3 425 425 Ubiquitination 1 19 1 1 FALSE FOXO3 1 O43524 IID00433 FALSE 20 1 1 MAPK11,12,13,14 FALSE p38 1 Q15759 2 P53778 3 O15264 4 Q16539 IID00280 FALSE 21 1 1 FALSE FOXO3(P) 1 O43524 IID00433 FALSE Phosphorylation 1 7 7 22 1 1 nucleus FALSE FOXO3(P) 1 O43524 IID00433 FALSE Phosphorylation 1 7 7 23 1 1 cytoplasm FALSE FOXO3(Ps) 1 O43524 IID00433 FALSE Phosphorylations 1 294 294 2 344 344 3 425 425 24 1 1 cytoplasm FALSE FOXO3(Ps) 1 O43524 IID00433 FALSE Phosphorylations 1 32 32 2 253 253 3 315 315 4 318 318 5 321 321 YWHAE 1 P62258 IID00512 FALSE 1 1 FALSE 2 3 19951971 2 4 FALSE 5 35874228 3 5 FALSE 6 7 20110348 4 7 FALSE 24 5 8 FALSE 9 21841822 6 9 TRUE 10 11 7 24 FALSE 12 13 20110348 8 13 FALSE 14 9 19 FALSE 20 21 26184557 10 21 FALSE 22 11 1 FALSE 15 16 18204439 19283669 12 16 FALSE 23 13 23 FALSE 17 18 21238503 1 1 result 3 1 2 operand 4 1 2 4 result 24 1 5 operand 8 1 3 8 result 14 1 9 operand 19 1