1.0.0 O95405-1 1 1 1 FALSE ZFYVE9 1 O95405 IID00112 FALSE 2 1 FALSE SMAD2 1 Q15796 IID00127 FALSE 3 1 FALSE TGF-beta_receptor_complex ligand-bound; activated e.g. ACVR1B(ALK4)/ACVR2A FALSE 2 1 1 FALSE ZFYVE9 1 O95405 IID00112 FALSE 1devB SMAD2 1 Q15796 IID00127 FALSE 1devA TGF-beta_receptor_complex FALSE 3 1 1 FALSE TGF-beta_receptor_complex FALSE 4 1 1 FALSE ZFYVE9 1 O95405 IID00112 FALSE SMAD2(Ps) 1 Q15796 IID00127 phosphorylated at the C-terminal SXS sequence FALSE Phosphorylations 1 465 465 2 467 467 TGF-beta_receptor_complex FALSE 5 1 1 FALSE ZFYVE9 1 O95405 IID00112 FALSE 2 1 FALSE SMAD2(Ps) 1 Q15796 IID00127 subsequently, forms a heterotrimeric complex with Smad4; the complex translocates to the nucleus and modulates the expression of target genes FALSE Phosphorylations 1 465 465 2 467 467 3 1 FALSE TGF-beta_receptor_complex FALSE 1 1 FALSE 2 10615055 28602823 30275343 9865696 2 2 TRUE 3 4 3 4 FALSE 5