1.0.0 P01106-3 1 1 1 FALSE MYC 1 P01106 IID00012 FALSE 2 1 1 FALSE MYC(P) 1 P01106 IID00012 phosphorylated at Ser-77 (pS62-MYC) FALSE Phosphorylation 1 77 77 3 1 1 FALSE MAPK 1 P28482 2 P27361 e.g. MAPK1, MAPK3 FALSE 2 FALSE CDK 1 P50750 e.g. CDK9 FALSE 3 FALSE DYRK 1 Q92630 e.g. DYRK2 FALSE 4 FALSE CAMK 1 Q13555 e.g. CaM kinase II gamma FALSE 4 1 1 FALSE MYC(Ps) 1 P01106 IID00012 phosphorylated at Thr-73, Ser-77 (pT58, pS62-MYC) FALSE Phosphorylations 1 77 77 2 73 73 5 1 1 FALSE GSK3A|B 1 P49840 2 P49841 IID00052 FALSE 6 1 1 FALSE MYC(Ps) 1 P01106 IID00012 phosphorylated at Thr-73, Ser-77, Thr-259, Thr-263 (pT58, pS62, pT244, pT248-MYC) FALSE Phosphorylations 1 77 77 2 73 73 3 259 259 4 263 263 7 1 1 FALSE Ser/Thr-Kinase not yet identified FALSE 8 1 1 FALSE MYC(Ps) 1 P01106 IID00012 FALSE Phosphorylations 1 77 77 2 73 73 3 259 259 4 263 263 2 1 SCF-Fbw7 ubiquitin ligase complex + Ubiquitin-conjugating enzyme E2 FALSE FBXW7 1 Q969H0 FALSE SKP1 1 P63208 FALSE CUL1 1 Q13616 IID00133 FALSE RBX1 1 P62877 IID00059 FALSE E2 FALSE 3 1 FALSE FBXW7 1 Q969H0 FALSE SKP1 1 P63208 FALSE CUL1 1 Q13616 IID00133 FALSE RBX1 1 P62877 IID00059 FALSE E2 FALSE 9 1 1 FALSE MYC(Ps) 1 P01106 IID00012 FALSE 7t1yC 7t1zC Phosphorylations 1 77 77 2 73 73 3 259 259 4 263 263 FBXW7 1 Q969H0 FALSE 7t1yB SKP1 1 P63208 FALSE 7t1yA CUL1 1 Q13616 IID00133 FALSE RBX1 1 P62877 IID00059 FALSE E2 FALSE FBXW7 1 Q969H0 FALSE 7t1zB SKP1 1 P63208 FALSE 7t1zA CUL1 1 Q13616 IID00133 FALSE RBX1 1 P62877 IID00059 FALSE E2 FALSE 10 1 1 FALSE MYC(Ps,Ub) 1 P01106 IID00012 FALSE Phosphorylations 1 77 77 2 73 73 3 259 259 4 263 263 Ubiquitination 1 FBXW7 1 Q969H0 FALSE SKP1 1 P63208 FALSE CUL1 1 Q13616 IID00133 FALSE RBX1 1 P62877 IID00059 FALSE E2 FALSE FBXW7 1 Q969H0 FALSE SKP1 1 P63208 FALSE CUL1 1 Q13616 IID00133 FALSE RBX1 1 P62877 IID00059 FALSE E2 FALSE 11 1 1 FALSE FBXW7 1 Q969H0 FALSE SKP1 1 P63208 FALSE CUL1 1 Q13616 IID00133 FALSE RBX1 1 P62877 IID00059 FALSE E2 FALSE FBXW7 1 Q969H0 FALSE SKP1 1 P63208 FALSE CUL1 1 Q13616 IID00133 FALSE RBX1 1 P62877 IID00059 FALSE E2 FALSE 12 1 1 FALSE MYC(Ps,Ub) 1 P01106 IID00012 undergoes proteasomal degradation FALSE Phosphorylations 1 77 77 2 73 73 3 259 259 4 263 263 Ubiquitination 1 2 1 FALSE FBXW7 1 Q969H0 FALSE SKP1 1 P63208 FALSE CUL1 1 Q13616 IID00133 FALSE RBX1 1 P62877 IID00059 FALSE E2 FALSE 3 1 FALSE FBXW7 1 Q969H0 FALSE SKP1 1 P63208 FALSE CUL1 1 Q13616 IID00133 FALSE RBX1 1 P62877 IID00059 FALSE E2 FALSE 1 1 FALSE 3 2 35089787 14563837 11018017 28697340 2 2 FALSE 5 4 3 4 FALSE 7 6 4 8 FALSE 9 5 9 TRUE 11 10 6 10 FALSE 12 1 3 result 6 1 4 operand 8 1