1.0.0 P04198-1 1 1 1 FALSE MYCN(Ps) 1 P04198 IID00766 FALSE Phosphorylations 1 58 58 2 62 62 2 1 SCF-FBXW7 Complex FALSE SKP1/CUL1/RBX1 1 P63208 2 Q13616 IID00133 3 P62877 IID00059 FALSE FBXW7 1 Q969H0 FALSE 2 1 1 FALSE MYCN(Ps) 1 P04198 IID00766 FALSE Phosphorylations 1 58 58 2 62 62 SKP1/CUL1/RBX1 1 P63208 2 Q13616 IID00133 3 P62877 IID00059 FALSE FBXW7 1 Q969H0 FALSE 3 1 1 FALSE SKP1/CUL1/RBX1 1 P63208 2 Q13616 IID00133 3 P62877 IID00059 FALSE FBXW7 1 Q969H0 FALSE 4 1 1 FALSE MYCN(Ps,Ub) 1 P04198 IID00766 undergoes proteasome-mediated degradation FALSE Phosphorylations 1 58 58 2 62 62 Ubiquitination 1 SKP1/CUL1/RBX1 1 P63208 2 Q13616 IID00133 3 P62877 IID00059 FALSE FBXW7 1 Q969H0 FALSE 5 1 1 FALSE MYCN 1 P04198 IID00766 FALSE 6 1 1 FALSE GSK3B 1 P49841 IID00052 FALSE 2 1 FALSE CCNB 1 P14635 IID00141 2 O95067 3 Q8WWL7 FALSE CDK1 1 P06493 FALSE 7 1 1 FALSE MYCN(Ps) 1 P04198 IID00766 FALSE Phosphorylations 1 58 58 2 62 62 8 1 1 FALSE MYCN 1 P04198 IID00766 FALSE 2 1 FALSE AURKA 1 O14965 IID00752 competes with SCF-FbxW7 for binding to unphosphorylated N-Myc FALSE 9 1 1 FALSE 5g1x 7ztl MYCN 1 P04198 IID00766 protected from proteasome-mediated degradation FALSE 5g1xB 7ztlB AURKA 1 O14965 IID00752 FALSE 5g1xA 7ztlA 1 5 FALSE 6 7 27837025 19111882 33981003 36601802 2 1 FALSE 2 3 2 TRUE 3 4 4 8 FALSE 9 1 1 result 7 1 2 operand 1 1 2 1 operand 5 1 4 operand 8 1