<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<sbgn xmlns="http://sbgn.org/libsbgn/0.2">
  <map language="process description">
    <extension>
      <selfEntry uniprot="P06239" iid="IID00770"/>
      <renderInformation id="renderInformation" program-name="sbgnviz" program-version="6.0.2" background-color="#00000000">
        <listOfColorDefinitions>
          <colorDefinition id="color_transparence" value="#ffffffff"/>
          <colorDefinition id="color_stroke" value="#555555"/>
          <colorDefinition id="color_white" value="#ffffff"/>
          <colorDefinition id="color_red" value="#ff0000"/>
          <colorDefinition id="color_association" value="#707070ff"/>
          <colorDefinition id="color_dissociation" value="#ffffff"/>
          <colorDefinition id="color_location" value="#e7effaff"/>
          <colorDefinition id="color_phenotype" value="#e7effaff"/>
          <colorDefinition id="color_complex" value="#e7effaff"/>
        </listOfColorDefinitions>
        <listOfStyles>
          <style id="macromolecule" idList="0 Node1 Node2 Node3 Node4 Node8 Node9 Node10 Node5 Node6 Node7 Node12 Node13 Node14 Node15 Node16">
            <g stroke="color_stroke" stroke-width="1.25" fill="color_transparence" font-size="11" font-family="monospace" font-weight="normal" font-style="normal" font-color="#000" background-image-opacity="1" background-opacity="1"/>
          </style>
          <style id="association" idList="0 Node11 Node18">
            <g stroke="color_stroke" stroke-width="1.25" fill="color_association" background-image-opacity="1" background-opacity="1"/>
          </style>
          <style id="edge" idList="0 Node1-Node11.1 Node2-Node11.1 Node3-Node11.1 Node11.2-Node4 Node7-Node17 Node4-Node18.1 Node5-Node18.1 Node6-Node18.1 Node18.2-Node7">
            <g stroke="color_stroke" stroke-width="1.25"/>
          </style>
          <style id="prop_phenotype" idList="0 Node17">
            <g stroke="color_stroke" stroke-width="1.25" fill="color_phenotype" font-size="11" font-family="monospace" font-weight="normal" font-style="normal" font-color="#000" background-image-opacity="1" background-opacity="1"/>
          </style>
        </listOfStyles>
      </renderInformation>
      <mapProperties>
        <compoundPadding>0</compoundPadding>
        <extraCompartmentPadding>14</extraCompartmentPadding>
        <extraComplexPadding>10</extraComplexPadding>
        <arrowScale>1.25</arrowScale>
        <showComplexName>true</showComplexName>
        <dynamicLabelSize>regular</dynamicLabelSize>
        <inferNestingOnLoad>false</inferNestingOnLoad>
        <fitLabelsToNodes>false</fitLabelsToNodes>
        <fitLabelsToInfoboxes>false</fitLabelsToInfoboxes>
        <recalculateLayoutOnComplexityManagement>true</recalculateLayoutOnComplexityManagement>
        <rearrangeOnComplexityManagement>true</rearrangeOnComplexityManagement>
        <animateOnDrawingChanges>true</animateOnDrawingChanges>
        <adjustNodeLabelFontSizeAutomatically>false</adjustNodeLabelFontSizeAutomatically>
        <enablePorts>true</enablePorts>
        <enableSIFTopologyGrouping>false</enableSIFTopologyGrouping>
        <allowCompoundNodeResize>true</allowCompoundNodeResize>
        <mapColorScheme>black_white</mapColorScheme>
        <mapColorSchemeStyle>solid</mapColorSchemeStyle>
        <mapName>Pathway #8</mapName>
        <highlightColor>#0B9BCD</highlightColor>
        <extraHighlightThickness>2</extraHighlightThickness>
      </mapProperties>
      <popperInfo>
        <glyph id="Node1">
          <entry uniprot="P06239" iid="IID00770"/>
        </glyph>
        <glyph id="Node3">
          <entry uniprot="P01730"/>
        </glyph>
        <glyph id="Node4">
          <pdb pdb_id="1q68"/>
        </glyph>
        <glyph id="Node9">
          <entry uniprot="P01730"/>
          <pdb pdb_id="1q68A"/>
        </glyph>
        <glyph id="Node10">
          <entry uniprot="P06239" iid="IID00770"/>
          <pdb pdb_id="1q68B"/>
        </glyph>
        <glyph id="Node13">
          <entry uniprot="P01730"/>
        </glyph>
        <glyph id="Node14">
          <entry uniprot="P06239" iid="IID00770"/>
        </glyph>
        <arc id="Node1-Node11.1">
          <process process_no="1"/>
        </arc>
        <arc id="Node2-Node11.1">
          <process process_no="1"/>
        </arc>
        <arc id="Node3-Node11.1">
          <process process_no="1"/>
        </arc>
        <arc id="Node11.2-Node4">
          <process process_no="1"/>
        </arc>
        <arc id="Node4-Node18.1">
          <process process_no="2"/>
        </arc>
        <arc id="Node5-Node18.1">
          <process process_no="2"/>
        </arc>
        <arc id="Node6-Node18.1">
          <process process_no="2"/>
        </arc>
        <arc id="Node18.2-Node7">
          <process process_no="2"/>
        </arc>
      </popperInfo>
      <isEdited>true</isEdited>
    </extension>
    <glyph id="Node17" class="phenotype" obj_id="4">
      <label text="positive regulation&#xA;of T cell receptor&#xA;signaling pathway"/>
      <bbox x="746.723065972772" y="92.93837263904192" w="171" h="30"/>
    </glyph>
    <glyph id="Node1" class="macromolecule" obj_id="1">
      <label text="LCK"/>
      <bbox x="-39.875" y="246.59375" w="90" h="30"/>
    </glyph>
    <glyph id="Node2" class="simple chemical" obj_id="1">
      <label text="Zn2+"/>
      <bbox x="-39.875" y="160.09375" w="90" h="30"/>
    </glyph>
    <glyph id="Node3" class="macromolecule" obj_id="1">
      <label text="CD4"/>
      <bbox x="-39.875" y="203.34375" w="90" h="30"/>
    </glyph>
    <glyph id="Node4" class="complex" obj_id="2 3">
      <bbox x="177.1540118334127" y="153.3829989145412" w="0" h="0"/>
      <glyph id="Node8" class="simple chemical" obj_id="2 3">
        <label text="Zn2+"/>
        <bbox x="183.7790118334127" y="160.00799891454122" w="90" h="30"/>
      </glyph>
      <glyph id="Node9" class="macromolecule" obj_id="2 3">
        <label text="CD4"/>
        <bbox x="183.7790118334127" y="203.25799891454122" w="90" h="30"/>
      </glyph>
      <glyph id="Node10" class="macromolecule" obj_id="2 3">
        <label text="LCK"/>
        <bbox x="183.7790118334127" y="246.5079989145412" w="90" h="30"/>
      </glyph>
    </glyph>
    <glyph id="Node11" class="association">
      <bbox x="116.4354071329075" y="208.19522851838514" w="15" h="15"/>
      <port id="Node11.1" x="125.5604071329075" y="217.32022851838514"/>
      <port id="Node11.2" x="125.5604071329075" y="217.32022851838514"/>
    </glyph>
    <glyph id="Node5" class="macromolecule" obj_id="3">
      <label text="TCR_complex"/>
      <bbox x="190.66150468676523" y="28.182330513753875" w="90" h="30"/>
    </glyph>
    <glyph id="Node6" class="macromolecule" obj_id="3">
      <label text="antigen-bound_MHC-II_complex"/>
      <bbox x="156.76297194563332" y="94.8104810739096" w="168" h="30"/>
    </glyph>
    <glyph id="Node7" class="complex" obj_id="4">
      <bbox x="455.3751870055839" y="56.62477817699381" w="0" h="0"/>
      <glyph id="Node12" class="simple chemical" obj_id="4">
        <label text="Zn2+"/>
        <bbox x="462.0001870055838" y="117.48848446669592" w="90" h="30"/>
      </glyph>
      <glyph id="Node13" class="macromolecule" obj_id="4">
        <label text="CD4"/>
        <bbox x="496.0388906226933" y="93.53467317560681" w="90" h="30"/>
      </glyph>
      <glyph id="Node14" class="macromolecule" obj_id="4">
        <label text="LCK"/>
        <bbox x="532.3857446082811" y="123.55473825357143" w="90" h="30"/>
      </glyph>
      <glyph id="Node15" class="macromolecule" obj_id="4">
        <label text="TCR_complex"/>
        <bbox x="621.4066534835615" y="93.64156615180161" w="90" h="30"/>
      </glyph>
      <glyph id="Node16" class="macromolecule" obj_id="4">
        <label text="antigen-bound_MHC-II_complex"/>
        <bbox x="513.2820231885719" y="63.249778176993814" w="168" h="30"/>
      </glyph>
    </glyph>
    <glyph id="Node18" class="association">
      <bbox x="387.6236690619624" y="95.9793959960176" w="15" h="15"/>
      <port id="Node18.1" x="396.7486690619624" y="105.1043959960176"/>
      <port id="Node18.2" x="396.7486690619624" y="105.1043959960176"/>
    </glyph>
    <arc id="Node1-Node11.1" class="consumption" source="Node1" target="Node11.1">
      <start x="0" y="0"/>
      <end x="0" y="0"/>
    </arc>
    <arc id="Node2-Node11.1" class="consumption" source="Node2" target="Node11.1">
      <start x="0" y="0"/>
      <end x="0" y="0"/>
    </arc>
    <arc id="Node3-Node11.1" class="consumption" source="Node3" target="Node11.1">
      <start x="0" y="0"/>
      <end x="0" y="0"/>
    </arc>
    <arc id="Node11.2-Node4" class="production" source="Node11.2" target="Node4">
      <start x="0" y="0"/>
      <end x="0" y="0"/>
    </arc>
    <arc id="Node7-Node17" class="modulation" source="Node7" target="Node17">
      <start x="0" y="0"/>
      <end x="0" y="0"/>
    </arc>
    <arc id="Node4-Node18.1" class="consumption" source="Node4" target="Node18.1">
      <start x="0" y="0"/>
      <end x="0" y="0"/>
    </arc>
    <arc id="Node5-Node18.1" class="consumption" source="Node5" target="Node18.1">
      <start x="0" y="0"/>
      <end x="0" y="0"/>
    </arc>
    <arc id="Node6-Node18.1" class="consumption" source="Node6" target="Node18.1">
      <start x="0" y="0"/>
      <end x="0" y="0"/>
    </arc>
    <arc id="Node18.2-Node7" class="production" source="Node18.2" target="Node7">
      <start x="0" y="0"/>
      <end x="0" y="0"/>
    </arc>
  </map>
  <formatOutput>1</formatOutput>
</sbgn>
