<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<sbgn xmlns="http://sbgn.org/libsbgn/0.2">
\t<map language="process description">
\t<extension><selfEntry uniprot="P16104" iid="IID00027"/><renderInformation id="renderInformation" program-name="sbgnviz" program-version="6.0.2" background-color="#00000000"><listOfColorDefinitions><colorDefinition id="color_transparence" value="#ffffffff"/><colorDefinition id="color_stroke" value="#555555"/><colorDefinition id="color_white" value="#ffffff"/><colorDefinition id="color_red" value="#ff0000"/><colorDefinition id="color_association" value="#707070ff"/><colorDefinition id="color_dissociation" value="#ffffff"/><colorDefinition id="color_location" value="#e7effaff"/><colorDefinition id="color_phenotype" value="#e7effaff"/><colorDefinition id="color_complex" value="#e7effaff"/></listOfColorDefinitions><listOfStyles><style id="macromolecule" idList="0 Node1 Node2 Node3 Node11 Node13 Node5 Node6 Node7 Node18 Node20"><g stroke="color_stroke" stroke-width="1.25" fill="color_transparence" font-size="11" font-family="monospace" font-weight="normal" font-style="normal" font-color="#000" background-image-opacity="1" background-opacity="1"/></style><style id="state_variable" idList="0 Node8 Node15 Node19"><g stroke="color_stroke" stroke-width="1" fill="color_white" font-size="9" font-family="monospace" font-weight="normal" font-style="normal" font-color="#0f0f0f"/></style><style id="prop_phenotype" idList="0 Node9 Node12 Node14 Node16"><g stroke="color_stroke" stroke-width="1.25" fill="color_phenotype" font-size="11" font-family="monospace" font-weight="normal" font-style="normal" font-color="#000" background-image-opacity="1" background-opacity="1"/></style><style id="edge" idList="0 Node3-Node9 Node1-Node10.1 Node2-Node10 Node10.2-Node3 Node11-Node12  Node13-Node14  Node5-Node16 Node3-Node17.1 Node4-Node17 Node17.2-Node5 Node5-Node21.1 Node6-Node21.1 Node21.2-Node7"><g stroke="color_stroke" stroke-width="1.25"/></style><style id="process" idList="0 Node10 Node4 Node17"><g stroke="color_stroke" stroke-width="1.25" fill="color_transparence" background-image-opacity="1" background-opacity="1"/></style><style id="association" idList="0 Node21"><g stroke="color_stroke" stroke-width="1.25" fill="color_association" background-image-opacity="1" background-opacity="1"/></style></listOfStyles></renderInformation><mapProperties><compoundPadding>0</compoundPadding><extraCompartmentPadding>14</extraCompartmentPadding><extraComplexPadding>10</extraComplexPadding><arrowScale>1.25</arrowScale><showComplexName>true</showComplexName><dynamicLabelSize>regular</dynamicLabelSize><inferNestingOnLoad>false</inferNestingOnLoad><fitLabelsToNodes>false</fitLabelsToNodes><fitLabelsToInfoboxes>false</fitLabelsToInfoboxes><recalculateLayoutOnComplexityManagement>true</recalculateLayoutOnComplexityManagement><rearrangeOnComplexityManagement>true</rearrangeOnComplexityManagement><animateOnDrawingChanges>true</animateOnDrawingChanges><adjustNodeLabelFontSizeAutomatically>false</adjustNodeLabelFontSizeAutomatically><enablePorts>true</enablePorts><enableSIFTopologyGrouping>false</enableSIFTopologyGrouping><allowCompoundNodeResize>true</allowCompoundNodeResize><mapColorScheme>black_white</mapColorScheme><mapColorSchemeStyle>solid</mapColorSchemeStyle><mapName>Pathway #8</mapName><highlightColor>#0B9BCD</highlightColor><extraHighlightThickness>2</extraHighlightThickness></mapProperties><popperInfo><glyph id="Node1"><entry uniprot="P16104" iid="IID00027"/></glyph><glyph id="Node2"><entry uniprot="Q9UIG0"/></glyph><glyph id="Node3"><entry uniprot="P16104" iid="IID00027"/></glyph><arc id="Node1-Node10.1"><process process_no="1"/></arc><arc id="Node2-Node10"><process process_no="1"/></arc><arc id="Node10.2-Node3"><process process_no="1"/></arc><glyph id="Node11"><entry uniprot="Q13315"/></glyph><glyph id="Node13"><entry uniprot="Q13535"/></glyph><glyph id="Node5"><entry uniprot="P16104" iid="IID00027"/></glyph><arc id="Node3-Node17.1"><process process_no="2"/></arc><arc id="Node4-Node17"><process process_no="2"/></arc><arc id="Node17.2-Node5"><process process_no="2"/></arc><glyph id="Node6"><entry uniprot="Q8NEM0" iid="IID00516"/></glyph><glyph id="Node7"><pdb pdb_id="3u3z"/></glyph><glyph id="Node18"><entry uniprot="P16104" iid="IID00027"/><pdb pdb_id="3u3zB"/><complex gene="MCPH1" iid1="IID00027" iid2="IID00516" cluster="190"/></glyph><glyph id="Node20"><entry uniprot="Q8NEM0" iid="IID00516"/><pdb pdb_id="3u3zA"/><complex gene="H2AFX" iid1="IID00516" iid2="IID00027" cluster="190"/></glyph><arc id="Node5-Node21.1"><process process_no="3"/></arc><arc id="Node6-Node21.1"><process process_no="3"/></arc><arc id="Node21.2-Node7"><process process_no="3"/></arc></popperInfo><isEdited>true</isEdited></extension><glyph id="Node9" class="phenotype" obj_id="3"><label text="pY143"/><bbox x="288.2706914227401" y="99.10443425155786" w="120" h="30"/></glyph><glyph id="Node12" class="phenotype" obj_id="4"><label text="activated upon&#10;DNA damage"/><bbox x="277.686884081885" y="-96.39629396161038" w="126" h="30"/></glyph><glyph id="Node14" class="phenotype" obj_id="4"><label text="activated upon&#10;DNA damage"/><bbox x="458.52069142274" y="-99.81308295279871" w="126" h="30"/></glyph><glyph id="Node16" class="phenotype" obj_id="5"><label text="di-gamma-H2AX&#10;(pS140, pY143)"/><bbox x="571.7287980281435" y="-5.9584174314420135" w="126" h="30"/></glyph><glyph id="Node1" class="macromolecule" obj_id="1"><label text="H2AX"/><bbox x="92.27117545972999" y="40.83334862389852" w="90" h="30"/></glyph><glyph id="Node2" class="macromolecule" obj_id="2"><label text="BAZ1B"/><bbox x="192.8964392219799" y="-38.14591169748005" w="90" h="30"/></glyph><glyph id="Node3" class="macromolecule" obj_id="3"><label text="H2AX"/><bbox x="301.8961169280175" y="25.25007454150542" w="90" h="30"/><glyph id="Node8" class="state variable"><state value="P"/><bbox x="0" y="0" w="12" h="12"/></glyph></glyph><glyph id="Node10" class="process"><bbox x="229.5835079827404" y="46.604214449682914" w="15" h="15"/><port id="Node10.1" x="238.7085079827404" y="55.729214449682914"/><port id="Node10.2" x="238.7085079827404" y="55.729214449682914"/></glyph><glyph id="Node4" class="or"><bbox x="429.7086570657513" y="4.645598240893172" w="15" h="15"/><port id="Node4.1" x="438.8336570657513" y="13.770598240893172"/><port id="Node4.2" x="438.8336570657513" y="13.770598240893172"/></glyph><glyph id="Node11" class="macromolecule" obj_id="4"><label text="ATM"/><bbox x="343.7915916522961" y="-46.812830658472706" w="90" h="30"/></glyph><glyph id="Node13" class="macromolecule" obj_id="4"><label text="ATR"/><bbox x="443.6876868365587" y="-46.58377675972452" w="90" h="30"/></glyph><glyph id="Node5" class="macromolecule" obj_id="5 6"><label text="H2AX"/><bbox x="501.2498600007274" y="27.145862003143137" w="90" h="30"/><glyph id="Node15" class="state variable"><state value="Ps"/><bbox x="0" y="0" w="12" h="12"/></glyph></glyph><glyph id="Node17" class="process"><bbox x="428.9999976158142" y="47.77083333333333" w="15" h="15"/><port id="Node17.1" x="438.1249976158142" y="56.89583333333333"/><port id="Node17.2" x="438.1249976158142" y="56.89583333333333"/></glyph><glyph id="Node6" class="macromolecule" obj_id="6"><label text="MCPH1"/><bbox x="508.8748485328034" y="130.10407301195477" w="90" h="30"/></glyph><glyph id="Node7" class="complex" obj_id="7"><bbox x="694.3327601835003" y="43.708151757871406" w="0" h="0"/><glyph id="Node18" class="macromolecule" obj_id="7"><label text="H2AX"/><bbox x="701.6869287614877" y="50.333151757871406" w="90" h="30"/><glyph id="Node19" class="state variable"><state value="Ps"/><bbox x="0" y="0" w="12" h="12"/></glyph></glyph><glyph id="Node20" class="macromolecule" obj_id="7"><label text="MCPH1"/><bbox x="700.9577601835003" y="102.52062308806154" w="90" h="30"/></glyph></glyph><glyph id="Node21" class="association"><bbox x="634.3328863306635" y="87.37476299623906" w="15" h="15"/><port id="Node21.1" x="643.4578863306635" y="96.49976299623906"/><port id="Node21.2" x="643.4578863306635" y="96.49976299623906"/></glyph><arc id="Node3-Node9" class="modulation" source="Node3" target="Node9"><start x="0" y="0"/><end x="0" y="0"/></arc><arc id="Node1-Node10.1" class="consumption" source="Node1" target="Node10.1"><start x="0" y="0"/><end x="0" y="0"/></arc><arc id="Node2-Node10" class="catalysis" source="Node2" target="Node10"><start x="0" y="0"/><end x="0" y="0"/></arc><arc id="Node10.2-Node3" class="production" source="Node10.2" target="Node3"><start x="0" y="0"/><end x="0" y="0"/></arc><arc id="Node11-Node12" class="modulation" source="Node11" target="Node12"><start x="0" y="0"/><end x="0" y="0"/></arc><arc id="Node4-Node11" class="logic arc" source="Node4" target="Node11"><start x="0" y="0"/><end x="0" y="0"/></arc><arc id="Node13-Node14" class="modulation" source="Node13" target="Node14"><start x="0" y="0"/><end x="0" y="0"/></arc><arc id="Node4-Node13" class="logic arc" source="Node4" target="Node13"><start x="0" y="0"/><end x="0" y="0"/></arc><arc id="Node5-Node16" class="modulation" source="Node5" target="Node16"><start x="0" y="0"/><end x="0" y="0"/></arc><arc id="Node3-Node17.1" class="consumption" source="Node3" target="Node17.1"><start x="0" y="0"/><end x="0" y="0"/></arc><arc id="Node4-Node17" class="catalysis" source="Node4" target="Node17"><start x="0" y="0"/><end x="0" y="0"/></arc><arc id="Node17.2-Node5" class="production" source="Node17.2" target="Node5"><start x="0" y="0"/><end x="0" y="0"/></arc><arc id="Node5-Node21.1" class="consumption" source="Node5" target="Node21.1"><start x="0" y="0"/><end x="0" y="0"/></arc><arc id="Node6-Node21.1" class="consumption" source="Node6" target="Node21.1"><start x="0" y="0"/><end x="0" y="0"/></arc><arc id="Node21.2-Node7" class="production" source="Node21.2" target="Node7"><start x="0" y="0"/><end x="0" y="0"/></arc></map>
<formatOutput>1</formatOutput></sbgn>

