1.0.0 P19525-1 1 1 1 monomer, autoinhibited FALSE EIF2AK2 1 P19525 IID00443 PKR FALSE 2 1 1 e.g., viral infection FALSE dsRNA FALSE 3 1 1 dimer FALSE EIF2AK2 1 P19525 IID00443 FALSE 4 1 1 active FALSE EIF2AK2(Ps) 1 P19525 IID00443 FALSE Phosphorylations 1 446 446 2 451 451 5 1 1 FALSE EIF2AK2(Ps) 1 P19525 IID00443 FALSE Phosphorylations 1 446 446 2 451 451 2 1 eIF2-alpha FALSE EIF2S1 1 P05198 IID00508 2 P20459 IID50184 FALSE 6 1 1 FALSE EIF2AK2(Ps) 1 P19525 IID00443 FALSE 2a19B 2a19C Phosphorylations 1 446 446 2 451 451 EIF2S1 1 P05198 IID00508 2 P20459 IID50184 FALSE 2a19A 7 1 1 FALSE EIF2AK2(Ps) 1 P19525 IID00443 FALSE Phosphorylations 1 446 446 2 451 451 8 1 1 inhibits viral replication FALSE EIF2AK2(Ps) 1 P19525 IID00443 FALSE Phosphorylations 1 446 446 2 451 451 EIF2S1(P) 1 P05198 IID00508 2 P20459 IID50184 FALSE Phosphorylation 1 52 52 1 1 FALSE 2 3 11337501 16179259 2 3 FALSE 3 4 3 5 FALSE 6 16179258 4 6 TRUE 7 8 16179259 1 2 result 4 1 3 operand 5 1