<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<sbgn xmlns="http://sbgn.org/libsbgn/0.2">
  <map language="process description">
    <extension>
      <selfEntry uniprot="P25604" iid=""/>
      <renderInformation id="renderInformation" program-name="sbgnviz" program-version="6.0.2" background-color="#00000000">
        <listOfColorDefinitions>
          <colorDefinition id="color_transparence" value="#ffffffff"/>
          <colorDefinition id="color_stroke" value="#555555"/>
          <colorDefinition id="color_white" value="#ffffff"/>
          <colorDefinition id="color_red" value="#ff0000"/>
          <colorDefinition id="color_association" value="#707070ff"/>
          <colorDefinition id="color_dissociation" value="#ffffff"/>
          <colorDefinition id="color_location" value="#e7effaff"/>
          <colorDefinition id="color_phenotype" value="#e7effaff"/>
          <colorDefinition id="color_complex" value="#e7effaff"/>
        </listOfColorDefinitions>
        <listOfStyles>
          <style id="macromolecule" idList="0 Node1 Node4 Node5 Node2 Node9 Node10 Node11 Node12 Node3 Node14 Node15 Node17 Node18 Node19 Node20">
            <g stroke="color_stroke" stroke-width="1.25" fill="color_transparence" font-size="11" font-family="monospace" font-weight="normal" font-style="normal" font-color="#000" background-image-opacity="1" background-opacity="1"/>
          </style>
          <style id="state_variable" idList="0 Node6 Node16">
            <g stroke="color_stroke" stroke-width="1" fill="color_white" font-size="9" font-family="monospace" font-weight="normal" font-style="normal" font-color="#0f0f0f"/>
          </style>
          <style id="prop_location" idList="0 Node7">
            <g stroke="color_stroke" stroke-width="1.25" fill="color_location" font-size="11" font-family="monospace" font-weight="normal" font-style="normal" font-color="#000" background-image-opacity="1" background-opacity="1"/>
          </style>
          <style id="edge" idList="0 Node1-Node7 Node4-Node8 Node2-Node13 Node3-Node21 Node17-Node22 Node1-Node23.1 Node2-Node23.1 Node23.2-Node3">
            <g stroke="color_stroke" stroke-width="1.25"/>
          </style>
          <style id="prop_complex" idList="0 Node8 Node13">
            <g stroke="color_stroke" stroke-width="1.25" fill="color_complex" font-size="11" font-family="monospace" font-weight="normal" font-style="normal" font-color="#000" background-image-opacity="1" background-opacity="1"/>
          </style>
          <style id="prop_phenotype" idList="0 Node21 Node22">
            <g stroke="color_stroke" stroke-width="1.25" fill="color_phenotype" font-size="11" font-family="monospace" font-weight="normal" font-style="normal" font-color="#000" background-image-opacity="1" background-opacity="1"/>
          </style>
          <style id="association" idList="0 Node23">
            <g stroke="color_stroke" stroke-width="1.25" fill="color_association" background-image-opacity="1" background-opacity="1"/>
          </style>
        </listOfStyles>
      </renderInformation>
      <mapProperties>
        <compoundPadding>0</compoundPadding>
        <extraCompartmentPadding>14</extraCompartmentPadding>
        <extraComplexPadding>10</extraComplexPadding>
        <arrowScale>1.25</arrowScale>
        <showComplexName>true</showComplexName>
        <dynamicLabelSize>regular</dynamicLabelSize>
        <inferNestingOnLoad>false</inferNestingOnLoad>
        <fitLabelsToNodes>false</fitLabelsToNodes>
        <fitLabelsToInfoboxes>false</fitLabelsToInfoboxes>
        <recalculateLayoutOnComplexityManagement>true</recalculateLayoutOnComplexityManagement>
        <rearrangeOnComplexityManagement>true</rearrangeOnComplexityManagement>
        <animateOnDrawingChanges>true</animateOnDrawingChanges>
        <adjustNodeLabelFontSizeAutomatically>false</adjustNodeLabelFontSizeAutomatically>
        <enablePorts>true</enablePorts>
        <enableSIFTopologyGrouping>false</enableSIFTopologyGrouping>
        <allowCompoundNodeResize>true</allowCompoundNodeResize>
        <mapColorScheme>black_white</mapColorScheme>
        <mapColorSchemeStyle>solid</mapColorSchemeStyle>
        <mapName>Pathway #8</mapName>
        <highlightColor>#0B9BCD</highlightColor>
        <extraHighlightThickness>2</extraHighlightThickness>
      </mapProperties>
      <popperInfo>
        <glyph id="Node4">
          <entry uniprot="P40343"/>
          <entry uniprot="P38753"/>
        </glyph>
        <glyph id="Node9">
          <entry uniprot="P25604"/>
          <pdb pdb_id="2p22A"/>
        </glyph>
        <glyph id="Node10">
          <entry uniprot="P42939"/>
          <pdb pdb_id="2p22D"/>
        </glyph>
        <glyph id="Node11">
          <entry uniprot="Q99176"/>
          <pdb pdb_id="2p22C"/>
        </glyph>
        <glyph id="Node12">
          <entry uniprot="Q02767"/>
          <pdb pdb_id="2p22B"/>
        </glyph>
        <glyph id="Node14">
          <entry uniprot="P40343"/>
          <entry uniprot="P38753"/>
          <pdb pdb_id="3r42B"/>
        </glyph>
        <glyph id="Node17">
          <entry uniprot="P25604"/>
          <pdb pdb_id="3r42A"/>
        </glyph>
        <glyph id="Node18">
          <entry uniprot="P42939"/>
        </glyph>
        <glyph id="Node19">
          <entry uniprot="Q99176"/>
        </glyph>
        <glyph id="Node20">
          <entry uniprot="Q02767"/>
        </glyph>
        <arc id="Node1-Node23.1">
          <process process_no="1"/>
        </arc>
        <arc id="Node2-Node23.1">
          <process process_no="1"/>
        </arc>
        <arc id="Node23.2-Node3">
          <process process_no="1"/>
        </arc>
      </popperInfo>
      <isEdited>true</isEdited>
    </extension>
    <glyph id="Node7" class="phenotype" obj_id="1">
      <label text="endosomal&#xA;membrane"/>
      <bbox x="-109.31844249979832" y="261.7254796151796" w="81" h="30"/>
    </glyph>
    <glyph id="Node8" class="phenotype" obj_id="1">
      <label text="VPS27/HSE1"/>
      <bbox x="-132.06336666181673" y="88.47679464801945" w="120" h="30"/>
    </glyph>
    <glyph id="Node13" class="phenotype" obj_id="1">
      <label text="ESCRT-I"/>
      <bbox x="4.57866547298525" y="-63.419884752032665" w="120" h="30"/>
    </glyph>
    <glyph id="Node21" class="phenotype" obj_id="2">
      <label text="ESCRT-I interacts&#xA;with both ESCRT-0&#xA;and cargo."/>
      <bbox x="313.11038076406135" y="116.5615459044667" w="153" h="30"/>
    </glyph>
    <glyph id="Node22" class="phenotype" obj_id="2">
      <label text="interacts&#xA;with VPS27"/>
      <bbox x="295.5252844271061" y="192.91546092139976" w="90" h="30"/>
    </glyph>
    <glyph id="Node1" class="complex" obj_id="1">
      <bbox x="-122.73949149971477" y="145.28182765334657" w="0" h="0"/>
      <glyph id="Node4" class="macromolecule" obj_id="1">
        <label text="ESCRT-0"/>
        <bbox x="-115.55849154010002" y="151.90682765334657" w="90" h="30"/>
      </glyph>
      <glyph id="Node5" class="macromolecule" obj_id="1">
        <label text="cargo_protein"/>
        <bbox x="-116.11449149971477" y="183.67630940575563" w="90" h="30"/>
        <glyph id="Node6" class="state variable">
          <state value="Ub"/>
          <bbox x="0" y="0" w="12" h="12"/>
        </glyph>
      </glyph>
    </glyph>
    <glyph id="Node2" class="complex" obj_id="1">
      <bbox x="9.8576129891469" y="-6.470606743274203" w="0" h="0"/>
      <glyph id="Node9" class="macromolecule" obj_id="1">
        <label text="STP22"/>
        <bbox x="16.4826129891469" y="120.71289426250095" w="90" h="30"/>
      </glyph>
      <glyph id="Node10" class="macromolecule" obj_id="1">
        <label text="MVB12"/>
        <bbox x="18.952762670124912" y="81.62457156323285" w="90" h="30"/>
      </glyph>
      <glyph id="Node11" class="macromolecule" obj_id="1">
        <label text="SRN2"/>
        <bbox x="20.59952912411029" y="42.53624886396463" w="90" h="30"/>
      </glyph>
      <glyph id="Node12" class="macromolecule" obj_id="1">
        <label text="VPS28"/>
        <bbox x="20.59952912411029" y="0.15439325672578263" w="90" h="30"/>
      </glyph>
    </glyph>
    <glyph id="Node3" class="complex" obj_id="2">
      <bbox x="160.94445570047708" y="66.9443344117957" w="0" h="0"/>
      <glyph id="Node14" class="macromolecule" obj_id="2">
        <label text="ESCRT-0"/>
        <bbox x="171.16124559393816" y="233.45049129832802" w="90" h="30"/>
      </glyph>
      <glyph id="Node15" class="macromolecule" obj_id="2">
        <label text="cargo_protein"/>
        <bbox x="170.7470881904718" y="267.35469662028504" w="90" h="30"/>
        <glyph id="Node16" class="state variable">
          <state value="Ub"/>
          <bbox x="0" y="0" w="12" h="12"/>
        </glyph>
      </glyph>
      <glyph id="Node17" class="macromolecule" obj_id="2">
        <label text="STP22"/>
        <bbox x="168.8326899940888" y="189.28504904549771" w="90" h="30"/>
      </glyph>
      <glyph id="Node18" class="macromolecule" obj_id="2">
        <label text="MVB12"/>
        <bbox x="167.56945570047705" y="149.55770037939567" w="90" h="30"/>
      </glyph>
      <glyph id="Node19" class="macromolecule" obj_id="2">
        <label text="SRN2"/>
        <bbox x="169.4643071408949" y="114.15741865063075" w="90" h="30"/>
      </glyph>
      <glyph id="Node20" class="macromolecule" obj_id="2">
        <label text="VPS28"/>
        <bbox x="170.28769036788742" y="73.56933441179568" w="90" h="30"/>
      </glyph>
    </glyph>
    <glyph id="Node23" class="association">
      <bbox x="58.276409836751256" y="182.95124581577798" w="15" h="15"/>
      <port id="Node23.1" x="67.40140983675126" y="192.07624581577798"/>
      <port id="Node23.2" x="67.40140983675126" y="192.07624581577798"/>
    </glyph>
    <arc id="Node1-Node7" class="modulation" source="Node1" target="Node7">
      <start x="0" y="0"/>
      <end x="0" y="0"/>
    </arc>
    <arc id="Node4-Node8" class="modulation" source="Node4" target="Node8">
      <start x="0" y="0"/>
      <end x="0" y="0"/>
    </arc>
    <arc id="Node2-Node13" class="modulation" source="Node2" target="Node13">
      <start x="0" y="0"/>
      <end x="0" y="0"/>
    </arc>
    <arc id="Node3-Node21" class="modulation" source="Node3" target="Node21">
      <start x="0" y="0"/>
      <end x="0" y="0"/>
    </arc>
    <arc id="Node17-Node22" class="modulation" source="Node17" target="Node22">
      <start x="0" y="0"/>
      <end x="0" y="0"/>
    </arc>
    <arc id="Node1-Node23.1" class="consumption" source="Node1" target="Node23.1">
      <start x="0" y="0"/>
      <end x="0" y="0"/>
    </arc>
    <arc id="Node2-Node23.1" class="consumption" source="Node2" target="Node23.1">
      <start x="0" y="0"/>
      <end x="0" y="0"/>
    </arc>
    <arc id="Node23.2-Node3" class="production" source="Node23.2" target="Node3">
      <start x="0" y="0"/>
      <end x="0" y="0"/>
    </arc>
  </map>
  <formatOutput>1</formatOutput>
</sbgn>
