<?xml version="1.0" encoding="utf-8"?>
<IDEAL>
  <Version>1.0.0</Version>
  <BiologicalPhenomenon>
    <IdealID/>
    <UniprotAccession>P25604-1</UniprotAccession>
    <Object>
      <obj_id>1</obj_id>
      <component>
        <component_id>1</component_id>
        <sub_component>
          <sub_component_id>1</sub_component_id>
          <location>endosomal membrane</location>
          <phenotype/>
          <complex/>
          <llps>FALSE</llps>
          <protein>
            <symbol>ESCRT-0</symbol>
            <uniprot_accessions>
              <uniprot_accessions_id>1</uniprot_accessions_id>
              <uniprot_accession>P40343</uniprot_accession>
              <ideal_id/>
            </uniprot_accessions>
            <uniprot_accessions>
              <uniprot_accessions_id>2</uniprot_accessions_id>
              <uniprot_accession>P38753</uniprot_accession>
              <ideal_id/>
            </uniprot_accessions>
            <location/>
            <phenotype/>
            <complex>VPS27/HSE1</complex>
            <llps>FALSE</llps>
          </protein>
          <protein>
            <symbol>cargo_protein(Ub)</symbol>
            <location/>
            <phenotype/>
            <complex/>
            <llps>FALSE</llps>
            <modification>
              <type>Ubiquitination</type>
              <region>
                <region_id>1</region_id>
                <region_start/>
                <region_end/>
              </region>
            </modification>
          </protein>
        </sub_component>
      </component>
      <component>
        <component_id>2</component_id>
        <sub_component>
          <sub_component_id>1</sub_component_id>
          <location/>
          <phenotype/>
          <complex>ESCRT-I</complex>
          <llps>FALSE</llps>
          <protein>
            <symbol>STP22</symbol>
            <uniprot_accessions>
              <uniprot_accessions_id>1</uniprot_accessions_id>
              <uniprot_accession>P25604</uniprot_accession>
              <ideal_id/>
            </uniprot_accessions>
            <location/>
            <phenotype/>
            <complex/>
            <llps>FALSE</llps>
            <pdb>
              <pdb_id>2p22A</pdb_id>
            </pdb>
          </protein>
          <protein>
            <symbol>MVB12</symbol>
            <uniprot_accessions>
              <uniprot_accessions_id>1</uniprot_accessions_id>
              <uniprot_accession>P42939</uniprot_accession>
              <ideal_id/>
            </uniprot_accessions>
            <location/>
            <phenotype/>
            <complex/>
            <llps>FALSE</llps>
            <pdb>
              <pdb_id>2p22D</pdb_id>
            </pdb>
          </protein>
          <protein>
            <symbol>SRN2</symbol>
            <uniprot_accessions>
              <uniprot_accessions_id>1</uniprot_accessions_id>
              <uniprot_accession>Q99176</uniprot_accession>
              <ideal_id/>
            </uniprot_accessions>
            <location/>
            <phenotype/>
            <complex/>
            <llps>FALSE</llps>
            <pdb>
              <pdb_id>2p22C</pdb_id>
            </pdb>
          </protein>
          <protein>
            <symbol>VPS28</symbol>
            <uniprot_accessions>
              <uniprot_accessions_id>1</uniprot_accessions_id>
              <uniprot_accession>Q02767</uniprot_accession>
              <ideal_id/>
            </uniprot_accessions>
            <location/>
            <phenotype/>
            <complex/>
            <llps>FALSE</llps>
            <pdb>
              <pdb_id>2p22B</pdb_id>
            </pdb>
          </protein>
        </sub_component>
      </component>
    </Object>
    <Object>
      <obj_id>2</obj_id>
      <component>
        <component_id>1</component_id>
        <sub_component>
          <sub_component_id>1</sub_component_id>
          <location/>
          <phenotype>ESCRT-I interacts with both ESCRT-0 and cargo.</phenotype>
          <complex/>
          <llps>FALSE</llps>
          <protein>
            <symbol>ESCRT-0</symbol>
            <uniprot_accessions>
              <uniprot_accessions_id>1</uniprot_accessions_id>
              <uniprot_accession>P40343</uniprot_accession>
              <ideal_id/>
            </uniprot_accessions>
            <uniprot_accessions>
              <uniprot_accessions_id>2</uniprot_accessions_id>
              <uniprot_accession>P38753</uniprot_accession>
              <ideal_id/>
            </uniprot_accessions>
            <location/>
            <phenotype/>
            <complex/>
            <llps>FALSE</llps>
            <pdb>
              <pdb_id>3r42B</pdb_id>
            </pdb>
          </protein>
          <protein>
            <symbol>cargo_protein(Ub)</symbol>
            <location/>
            <phenotype/>
            <complex/>
            <llps>FALSE</llps>
            <modification>
              <type>Ubiquitination</type>
              <region>
                <region_id>1</region_id>
                <region_start/>
                <region_end/>
              </region>
            </modification>
          </protein>
          <protein>
            <symbol>STP22</symbol>
            <uniprot_accessions>
              <uniprot_accessions_id>1</uniprot_accessions_id>
              <uniprot_accession>P25604</uniprot_accession>
              <ideal_id/>
            </uniprot_accessions>
            <location/>
            <phenotype>interacts with VPS27</phenotype>
            <complex/>
            <llps>FALSE</llps>
            <pdb>
              <pdb_id>3r42A</pdb_id>
            </pdb>
          </protein>
          <protein>
            <symbol>MVB12</symbol>
            <uniprot_accessions>
              <uniprot_accessions_id>1</uniprot_accessions_id>
              <uniprot_accession>P42939</uniprot_accession>
              <ideal_id/>
            </uniprot_accessions>
            <location/>
            <phenotype/>
            <complex/>
            <llps>FALSE</llps>
          </protein>
          <protein>
            <symbol>SRN2</symbol>
            <uniprot_accessions>
              <uniprot_accessions_id>1</uniprot_accessions_id>
              <uniprot_accession>Q99176</uniprot_accession>
              <ideal_id/>
            </uniprot_accessions>
            <location/>
            <phenotype/>
            <complex/>
            <llps>FALSE</llps>
          </protein>
          <protein>
            <symbol>VPS28</symbol>
            <uniprot_accessions>
              <uniprot_accessions_id>1</uniprot_accessions_id>
              <uniprot_accession>Q02767</uniprot_accession>
              <ideal_id/>
            </uniprot_accessions>
            <location/>
            <phenotype/>
            <complex/>
            <llps>FALSE</llps>
          </protein>
        </sub_component>
      </component>
    </Object>
    <Process>
      <process_id>1</process_id>
      <operand_obj_id>1</operand_obj_id>
      <included_operand>FALSE</included_operand>
      <operator_obj_id/>
      <result_obj_id>2</result_obj_id>
      <pubmed>
        <pubmed_id>21763610</pubmed_id>
      </pubmed>
    </Process>
  </BiologicalPhenomenon>
</IDEAL>

