1.0.0 P46937-1 1 1 1 FALSE YAP1 1 P46937 IID00304 cytoplasm FALSE 2 1 1 activated by STK4|3 (MST1|2)-mediated phosphorylation. FALSE LATS1|2 1 O95835 2 Q9NRM7 FALSE MOB1A|B 1 Q9H8S9 IID00737 2 Q7L9L4 FALSE 3 1 1 FALSE YAP1(Ps) 1 P46937 IID00304 phosphorylation sites by LAST1|2: S61, S109, S127, S164, S397 FALSE Phosphorylations 1 4 1 1 FALSE YAP1 1 P46937 IID00304 nucleus FALSE 5 1 1 FALSE YAP1(Ps) 1 P46937 IID00304 FALSE Phosphorylations 1 127 127 2 1 FALSE SFN 1 P31947 IID00301 FALSE 6 1 1 YAP cytoplasmic retention FALSE 3mhr YAP1(Ps) 1 P46937 IID00304 S127 phosphorylation-dependent 14-3-3 binding FALSE 3mhrP Phosphorylations 1 127 127 SFN 1 P31947 IID00301 FALSE 3mhrA 7 1 1 FALSE CSNK1D|E 1 P48730 2 P49674 recognises S397-phosphorylated YAP and phosphorylates S400 and S403. FALSE 8 1 1 FALSE YAP1(Ps) 1 P46937 IID00304 degraded by SCF-beta-TRCP-mediated ubiquitination. FALSE Phosphorylations 1 397 397 2 400 400 3 403 403 9 1 1 FALSE YAP1 1 P46937 IID00304 FALSE 2 1 FALSE TEAD4 1 Q15561 FALSE 10 1 1 transcriptional activation of target genes FALSE 6ge3 6q2x YAP1 1 P46937 IID00304 FALSE 6ge3L 6q2xL TEAD4 1 Q15561 FALSE 6ge3A 6q2xA 1 1 FALSE 2 3 35701841 20048001 2 1 FALSE 4 3 5 FALSE 6 20823509 4 3 FALSE 7 8 5 9 FALSE 10 30058229 31235263 1 1 result 3 1 3 operand 5 1 2 2 result 4 1 5 operand 9 1