1.0.0 Q15788-1 1 1 1 FALSE NCOA1 1 Q15788 IID00083 FALSE 2 1 FALSE NR-dimer 1 G1RH57 2 P03372 IID00013 3 P04150 IID00014 4 P19793 IID00031 5 P37231 IID00041 6 P41235 IID00045 7 P62508 IID00057 8 Q92731 IID00091 9 Q13133 IID00243 10 O75469 IID00361 11 P10276 IID00365 12 P55055 IID00373 13 Q07869 IID00382 14 Q96RI1 IID00391 15 P10826 IID00439 16 Q14994 IID00475 17 P08235 IID00702 18 P45446 IID50142 19 P11473 NR: nuclear receptor, such as for steroids (PGR, GR, ER), retinoids (RXRs), thyroid hormone (TRs) and prostanoids (PPARs); ligand-bound form FALSE 2 1 1 transcriptional activation of target genes FALSE 1pzl 2a3i 2prg 3bqd 3cwd 3kmr 3ols 3uud 4dm8 NCOA1 1 Q15788 IID00083 binds NR using LXXLL motifs; plays a central role in creating a multisubunit coactivator complex, which probably acts via remodeling of chromatin FALSE 1pzlB 2a3iB 2prgC 3bqdB 3cwdC 3kmrC 3olsC 3uudC 4dm8C NR-dimer 1 G1RH57 2 P03372 IID00013 3 P04150 IID00014 4 P19793 IID00031 5 P37231 IID00041 6 P41235 IID00045 7 P62508 IID00057 8 Q92731 IID00091 9 Q13133 IID00243 10 O75469 IID00361 11 P10276 IID00365 12 P55055 IID00373 13 Q07869 IID00382 14 Q96RI1 IID00391 15 P10826 IID00439 16 Q14994 IID00475 17 P08235 IID00702 18 P45446 IID50142 19 P11473 FALSE 1 1 FALSE 2 14982928 16061183 9744270 18160712 18604218 20543827 20922740 22927406 22355136 28493531