1.0.0 Q15797-2 1 1 1 FALSE SMAD1 1 Q15797 IID00174 FALSE 2 1 1 FALSE TGF-beta_receptor_complex ligand-bound heterotetrameric receptor complex; activated e.g. BMPR1A(ALK3)/BMPR2 FALSE 3 1 1 FALSE SMAD1(Ps) 1 Q15797 IID00174 phosphorylated at the C-terminal SXS sequence FALSE Phosphorylations 1 463 463 2 465 465 4 1 1 FALSE SMAD1(Ps) 1 Q15797 IID00174 FALSE Phosphorylations 1 463 463 2 465 465 2 1 FALSE STUB1 1 Q9UNE7 2 Q9WUD1 negative regulator of TGF-beta signaling FALSE 5 1 1 FALSE 3q4a SMAD1(Ps) 1 Q15797 IID00174 FALSE 3q4aC Phosphorylations 1 463 463 2 465 465 STUB1 1 Q9UNE7 2 Q9WUD1 FALSE 3q4aB 6 1 1 FALSE SMAD1(Ps,Ub) 1 Q15797 IID00174 FALSE Phosphorylations 1 463 463 2 465 465 Ubiquitination 1 STUB1 1 Q9UNE7 2 Q9WUD1 FALSE 7 1 1 FALSE STUB1 1 Q9UNE7 2 Q9WUD1 FALSE 8 1 1 FALSE SMAD1(Ps,Ub) 1 Q15797 IID00174 proteasomal degradation FALSE Phosphorylations 1 463 463 2 465 465 Ubiquitination 1 2 1 FALSE STUB1 1 Q9UNE7 2 Q9WUD1 FALSE 1 1 FALSE 2 3 11779505 21454478 29769446 25705796 34026818 2 4 FALSE 5 3 5 TRUE 7 6 4 6 FALSE 8 1 1 result 3 1 2 operand 4 1