<?xml version="1.0" encoding="utf-8"?>
<IDEAL>
  <Version>1.0.0</Version>
  <BiologicalPhenomenon>
    <IdealID/>
    <UniprotAccession>Q99ZW2-2</UniprotAccession>
    <Object>
      <obj_id>1</obj_id>
      <component>
        <component_id>1</component_id>
        <sub_component>
          <sub_component_id>1</sub_component_id>
          <location/>
          <phenotype/>
          <complex/>
          <llps>FALSE</llps>
          <protein>
            <symbol>cas9</symbol>
            <uniprot_accessions>
              <uniprot_accessions_id>1</uniprot_accessions_id>
              <uniprot_accession>Q99ZW2</uniprot_accession>
              <ideal_id>IID90040</ideal_id>
            </uniprot_accessions>
            <location/>
            <phenotype/>
            <complex/>
            <llps>FALSE</llps>
            <pdb>
              <pdb_id>4cmpA</pdb_id>
            </pdb>
            <pdb>
              <pdb_id>4cmqA</pdb_id>
            </pdb>
          </protein>
        </sub_component>
      </component>
      <component>
        <component_id>2</component_id>
        <sub_component>
          <sub_component_id>1</sub_component_id>
          <location/>
          <phenotype/>
          <complex/>
          <llps>FALSE</llps>
          <nucleic_acid>
            <symbol>sgRNA</symbol>
            <location/>
            <phenotype/>
            <complex/>
            <llps>FALSE</llps>
          </nucleic_acid>
        </sub_component>
      </component>
      <component>
        <component_id>3</component_id>
        <sub_component>
          <sub_component_id>1</sub_component_id>
          <location/>
          <phenotype/>
          <complex/>
          <llps>FALSE</llps>
          <protein>
            <symbol>acrIIA4|acrIIA2</symbol>
            <uniprot_accessions>
              <uniprot_accessions_id>1</uniprot_accessions_id>
              <uniprot_accession>A0A247D711</uniprot_accession>
              <ideal_id/>
            </uniprot_accessions>
            <uniprot_accessions>
              <uniprot_accessions_id>2</uniprot_accessions_id>
              <uniprot_accession>A0A0E0UT28</uniprot_accession>
              <ideal_id/>
            </uniprot_accessions>
            <uniprot_accessions>
              <uniprot_accessions_id>3</uniprot_accessions_id>
              <uniprot_accession>A0A459NDX2</uniprot_accession>
              <ideal_id/>
            </uniprot_accessions>
            <location/>
            <phenotype/>
            <complex/>
            <llps>FALSE</llps>
          </protein>
        </sub_component>
      </component>
    </Object>
    <Object>
      <obj_id>2</obj_id>
      <component>
        <component_id>1</component_id>
        <sub_component>
          <sub_component_id>1</sub_component_id>
          <location/>
          <phenotype/>
          <complex/>
          <llps>FALSE</llps>
          <pdb>
            <pdb_id>5vw1</pdb_id>
          </pdb>
          <pdb>
            <pdb_id>5xbl</pdb_id>
          </pdb>
          <pdb>
            <pdb_id>6ifo</pdb_id>
          </pdb>
          <protein>
            <symbol>cas9</symbol>
            <uniprot_accessions>
              <uniprot_accessions_id>1</uniprot_accessions_id>
              <uniprot_accession>Q99ZW2</uniprot_accession>
              <ideal_id>IID90040</ideal_id>
            </uniprot_accessions>
            <location/>
            <phenotype>cannot bind to target DNA</phenotype>
            <complex/>
            <llps>FALSE</llps>
            <pdb>
              <pdb_id>5vw1A</pdb_id>
            </pdb>
            <pdb>
              <pdb_id>5xblA</pdb_id>
            </pdb>
            <pdb>
              <pdb_id>6ifoA</pdb_id>
            </pdb>
          </protein>
          <nucleic_acid>
            <symbol>sgRNA</symbol>
            <location/>
            <phenotype/>
            <complex/>
            <llps>FALSE</llps>
            <pdb>
              <pdb_id>5vw1C</pdb_id>
            </pdb>
            <pdb>
              <pdb_id>5xblB</pdb_id>
            </pdb>
            <pdb>
              <pdb_id>6ifoC</pdb_id>
            </pdb>
          </nucleic_acid>
          <protein>
            <symbol>acrIIA4|acrIIA2</symbol>
            <uniprot_accessions>
              <uniprot_accessions_id>1</uniprot_accessions_id>
              <uniprot_accession>A0A247D711</uniprot_accession>
              <ideal_id/>
            </uniprot_accessions>
            <uniprot_accessions>
              <uniprot_accessions_id>2</uniprot_accessions_id>
              <uniprot_accession>A0A0E0UT28</uniprot_accession>
              <ideal_id/>
            </uniprot_accessions>
            <uniprot_accessions>
              <uniprot_accessions_id>3</uniprot_accessions_id>
              <uniprot_accession>A0A459NDX2</uniprot_accession>
              <ideal_id/>
            </uniprot_accessions>
            <location/>
            <phenotype/>
            <complex/>
            <llps>FALSE</llps>
            <pdb>
              <pdb_id>5vw1B</pdb_id>
            </pdb>
            <pdb>
              <pdb_id>5xblD</pdb_id>
            </pdb>
            <pdb>
              <pdb_id>6ifoE</pdb_id>
            </pdb>
          </protein>
        </sub_component>
      </component>
    </Object>
    <Process>
      <process_id>1</process_id>
      <operand_obj_id>1</operand_obj_id>
      <included_operand>FALSE</included_operand>
      <operator_obj_id/>
      <result_obj_id>2</result_obj_id>
      <pubmed>
        <pubmed_id>24505130</pubmed_id>
      </pubmed>
      <pubmed>
        <pubmed_id>28602637</pubmed_id>
      </pubmed>
      <pubmed>
        <pubmed_id>28706995</pubmed_id>
      </pubmed>
      <pubmed>
        <pubmed_id>28448066</pubmed_id>
      </pubmed>
      <pubmed>
        <pubmed_id>30606466</pubmed_id>
      </pubmed>
    </Process>
  </BiologicalPhenomenon>
</IDEAL>

