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IID00004
 UniprotO14717
ProteintRNA (cytosine(38)-C(5))-methyltransferase
GeneTRDMT1
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
391
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 2-189,237-391 Monomer :
 Evidence X-RAY 1g55 A Reference
       Region 1g55 A 2-78 order
       Region 1g55 A 79-96 disorder
       Region 1g55 A 97-188 order
       Region 1g55 A 189-189 disorder
       Region 1g55 A 237-247 disorder
       Region 1g55 A 248-391 order
 
Prediction
NeProc
Disorder 243-247
Order 1-242,248-391
ProS 243-247
AlphaFold
Disorder 79-93,189-230
Order 1-78,94-188,231-391
Pfam Hmmer
PF00145 4-391 7.8e-18
Function
Function in SwissProt
Specifically methylates cytosine 38 in the anticodon loop of tRNA(Asp) (PubMed:16424344). Has higher activity on tRNA(Asp) modified with queuosine at position 34 (PubMed:30093495).