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IID00025
 UniprotP14921
ProteinProtein C-ets-1
GeneETS1
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
441
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 276-441 Homo dimer :
 Evidence X-RAY 1gvj A Reference
       Region 1gvj A 297-436 order
       Region 1gvj A 437-441 disorder
 Evidence X-RAY 1gvj B Reference
       Region 1gvj B 297-441 order
 Evidence X-RAY 3mfk A Reference
       Region 3mfk A 280-301 disorder
       Region 3mfk A 302-439 order
       Region 3mfk A 440-441 disorder
 Evidence X-RAY 3mfk B Reference
       Region 3mfk B 280-301 disorder
       Region 3mfk B 302-437 order
       Region 3mfk B 438-441 disorder
 Evidence X-RAY 2nny A Reference
       Region 2nny A 280-307 disorder
       Region 2nny A 308-436 order
       Region 2nny A 437-441 disorder
 Evidence X-RAY 2nny B Reference
       Region 2nny B 280-307 disorder
       Region 2nny B 308-436 order
       Region 2nny B 437-441 disorder
 Evidence X-RAY 3ri4 A Reference
       Region 3ri4 A 280-301 disorder
       Region 3ri4 A 302-437 order
       Region 3ri4 A 438-441 disorder
 Evidence X-RAY 3ri4 D Reference
       Region 3ri4 D 280-301 disorder
       Region 3ri4 D 302-437 order
       Region 3ri4 D 438-441 disorder
 Evidence X-RAY 3wtz A Reference
       Region 3wtz A 276-300 disorder
       Region 3wtz A 301-310 order
       Region 3wtz A 311-315 disorder
       Region 3wtz A 316-440 order
       Region 3wtz A 441-441 disorder
 Evidence X-RAY 3wtz B Reference
       Region 3wtz B 276-300 disorder
       Region 3wtz B 301-436 order
       Region 3wtz B 437-441 disorder
 Evidence X-RAY 3wu0 A Reference
       Region 3wu0 A 276-300 disorder
       Region 3wu0 A 301-440 order
       Region 3wu0 A 441-441 disorder
 Evidence X-RAY 3wu0 B Reference
       Region 3wu0 B 276-300 disorder
       Region 3wu0 B 301-436 order
       Region 3wu0 B 437-441 disorder
Seq 276-441 Hetero trimer :
 Evidence X-RAY 3wts C Reference
       Region 3wts C 276-318 disorder
       Region 3wts C 319-436 order
       Region 3wts C 437-441 disorder
 Evidence X-RAY 3wts H Reference
       Region 3wts H 276-332 disorder
       Region 3wts H 333-433 order
       Region 3wts H 434-441 disorder
 Evidence X-RAY 3wtt C Reference
       Region 3wtt C 276-318 disorder
       Region 3wtt C 319-436 order
       Region 3wtt C 437-441 disorder
 Evidence X-RAY 3wtt H Reference
       Region 3wtt H 276-332 disorder
       Region 3wtt H 333-425 order
       Region 3wtt H 426-441 disorder
 Evidence X-RAY 3wtu C Reference
       Region 3wtu C 276-318 disorder
       Region 3wtu C 319-436 order
       Region 3wtu C 437-441 disorder
 Evidence X-RAY 3wtu H Reference
       Region 3wtu H 276-332 disorder
       Region 3wtu H 333-433 order
       Region 3wtu H 434-441 disorder
 Evidence X-RAY 3wtv C Reference
       Region 3wtv C 276-318 disorder
       Region 3wtv C 319-436 order
       Region 3wtv C 437-441 disorder
 Evidence X-RAY 3wtv H Reference
       Region 3wtv H 276-332 disorder
       Region 3wtv H 333-433 order
       Region 3wtv H 434-441 disorder
 Evidence X-RAY 3wtw C Reference
       Region 3wtw C 276-318 disorder
       Region 3wtw C 319-436 order
       Region 3wtw C 437-441 disorder
 Evidence X-RAY 3wtw H Reference
       Region 3wtw H 276-332 disorder
       Region 3wtw H 333-433 order
       Region 3wtw H 434-441 disorder
 Evidence X-RAY 3wtx C Reference
       Region 3wtx C 276-333 disorder
       Region 3wtx C 334-436 order
       Region 3wtx C 437-441 disorder
 Evidence X-RAY 3wtx H Reference
       Region 3wtx H 276-333 disorder
       Region 3wtx H 334-433 order
       Region 3wtx H 434-441 disorder
 Evidence X-RAY 3wty C Reference
       Region 3wty C 276-318 disorder
       Region 3wty C 319-436 order
       Region 3wty C 437-441 disorder
 Evidence X-RAY 3wty H Reference
       Region 3wty H 276-332 disorder
       Region 3wty H 333-433 order
       Region 3wty H 434-441 disorder
Seq 296-441 Hetero dimer :
 Evidence X-RAY 4l0y B Reference
       Region 4l0y B 296-333 disorder
       Region 4l0y B 334-437 order
       Region 4l0y B 438-441 disorder
 Evidence X-RAY 3wu1 B Reference
       Region 3wu1 B 333-437 order
       Region 3wu1 B 438-441 disorder
Seq 296-441 Hetero dimer : Q03347
 Evidence X-RAY 4l0z B Reference
       Region 4l0z B 296-331 disorder
       Region 4l0z B 332-432 order
       Region 4l0z B 433-441 disorder
 Evidence X-RAY 4l18 B Reference
       Region 4l18 B 296-332 disorder
       Region 4l18 B 333-439 order
       Region 4l18 B 440-441 disorder
 Evidence X-RAY 4l18 F Reference
       Region 4l18 F 296-331 disorder
       Region 4l18 F 332-437 order
       Region 4l18 F 438-441 disorder
Seq 320-415 Monomer :
 Evidence NMR 2stw A Reference
       Region 2stw A 320-415 order
 Evidence NMR 2stt A Reference
       Region 2stt A 320-415 order
       Region 2stt A 331-333 high_rmsd
Seq 331-440 Hetero dimer :
 Evidence X-RAY 4lg0 B Reference
       Region 4lg0 B 331-332 disorder
       Region 4lg0 B 333-438 order
       Region 4lg0 B 439-440 disorder
Seq 331-441 Hetero dimer : Q00653
 Evidence X-RAY 5zmc B Reference
       Region 5zmc B 331-331 disorder
       Region 5zmc B 332-437 order
       Region 5zmc B 438-441 disorder
Seqphosphorylation
    223-223 Phosphotyrosine
    38-38 Phosphothreonine; by MAPK
    251-251 Phosphoserine
    265-265 Phosphothreonine
    254-254 Phosphoserine
    270-270 Phosphoserine
    267-267 Phosphoserine
    282-282 Phosphoserine
    285-285 Phosphoserine
Seqacetylation
    15-15 N6-acetyllysine; alternate
    8-8 N6-acetyllysine; alternate
    305-305 N6-acetyllysine
 
Prediction
NeProc
Disorder 1-42,140-332,439-441
Order 43-139,333-438
ProS 1-25,31-42,140-202,209-292,305-310,316-332,439-441
AlphaFold
Disorder 1-48,136-301,310-317,439-441
Order 49-135,302-309,318-438
Pfam Hmmer
PF02198 53-136 2.1e-48
PF00178 334-417 3.3e-64
SEG 266-278
Function
Function in SwissProt
Acts as a dominant-negative for isoform c-ETS-1A.