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IID00027  Histone H2AX (Homo sapiens) P16104
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
143
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 78-86 Hetero dodecamer : P17693
 Evidence X-RAY 2d31 C Reference
       Region 2d31 C 78-86 order
 Evidence X-RAY 2d31 F Reference
       Region 2d31 F 78-86 order
Seq 78-86 Hetero trimer : P17693
 Evidence X-RAY 1ydp P Reference
       Region 1ydp P 78-86 order
Seq 78-86 Hetero tetramer : P17693
 Evidence X-RAY 2dyp C Reference
       Region 2dyp C 78-86 order
Seq 134-143 Hetero dimer : IID00483Complex
 Evidence X-RAY 3sqd C Reference
       Region 3sqd C 134-143 order
 Evidence X-RAY 3sqd D Reference
       Region 3sqd D 134-139 disorder
       Region 3sqd D 140-143 order
Seq 134-143 Hetero dimer : IID00516Complex
 Evidence X-RAY 3shv C Reference
       Region 3shv C 134-137 disorder
       Region 3shv C 138-143 order
 Evidence X-RAY 3shv D Reference
       Region 3shv D 134-137 disorder
       Region 3shv D 138-143 order
 Evidence X-RAY 3szm I Reference
       Region 3szm I 134-137 disorder
       Region 3szm I 138-143 order
 Evidence X-RAY 3szm J Reference
       Region 3szm J 134-137 disorder
       Region 3szm J 138-143 order
 Evidence X-RAY 3szm K Reference
       Region 3szm K 134-138 disorder
       Region 3szm K 139-143 order
 Evidence X-RAY 3szm L Reference
       Region 3szm L 134-137 disorder
       Region 3szm L 138-143 order
 Evidence X-RAY 3szm M Reference
       Region 3szm M 134-137 disorder
       Region 3szm M 138-143 order
 Evidence X-RAY 3szm N Reference
       Region 3szm N 134-137 disorder
       Region 3szm N 138-143 order
 Evidence X-RAY 3szm O Reference
       Region 3szm O 134-137 disorder
       Region 3szm O 138-143 order
 Evidence X-RAY 3szm P Reference
       Region 3szm P 134-138 disorder
       Region 3szm P 139-143 order
 Evidence X-RAY 3u3z B Reference
       Region 3u3z B 140-143 order
Seq 134-143 Hetero dimer : IID00568Complex
 Evidence X-RAY 2azm C Reference
       Region 2azm C 134-138 disorder
       Region 2azm C 139-143 order
 Evidence X-RAY 2azm D Reference
       Region 2azm D 134-138 disorder
       Region 2azm D 139-143 order
SeqProS possible 134-143 Same region of Saccharomyces homolog (P04908, 94%identity) is disordered in the free state. Hetero dimer : IID00483Complex
       Region 3sqd C 134-143 order
       Region 3sqd D 140-143 order
SeqProS possible 138-143 Same region of Saccharomyces homolog (P04908, 94%identity) is disordered in the free state. Hetero dimer : IID00516Complex
       Region 3shv C 138-143 order
       Region 3shv D 138-143 order
       Region 3szm I 138-143 order
       Region 3szm J 138-143 order
       Region 3szm K 139-143 order
       Region 3szm L 138-143 order
       Region 3szm M 138-143 order
       Region 3szm N 138-143 order
       Region 3szm O 138-143 order
       Region 3szm P 139-143 order
       Region 3u3z B 140-143 order
SeqProS possible 139-143 Same region of Saccharomyces homolog (P04908, 94%identity) is disordered in the free state. Hetero dimer : IID00568Complex
       Region 2azm C 139-143 order
       Region 2azm D 139-143 order
Seqphosphorylation
    2-2 Phosphoserine
    122-122 Phosphoserine
    140-140 Phosphoserine; by ATM
    143-143 Phosphotyrosine; by WSTF
Seqacetylation
    2-2 N-acetylserine
    6-6 N6-acetyllysine
    10-10 N6-acetyllysine
    37-37 N6-acetyllysine
 
Prediction
DICHOT
Disorder 1-22,125-143
Known Domain 23-124
SCOPe RPS-Blast
     1q9cA 10-98 4e-27 a.22.1.3 Chrac-14
SCOP Hmmer
     1q9cA_ 2-99 7.1e-50 a.22.1.3 Chrac-14
Pfam RPS-Blast
     PF00125 65-89 4e-04 Core histone H2A/H2B/H3/H4
     PF16211 92-121 8e-09 C-terminus of histone H2A
Pfam Hmmer
    PF00125 5-89 1.2e-20 Core histone H2A/H2B/H3/H4
    PF16211 92-124 4.6e-24 C-terminus of histone H2A