Search Keyword:


Search option:


IID00039  Catenin beta-1 (Homo sapiens) P35222
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
781
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 19-44 Monomer :
 Evidence NMR 2g57 A Reference
       Region 2g57 A 19-44 order
       Region 2g57 A 19-20 high_rmsd
       Region 2g57 A 36-44 high_rmsd
Seq 19-44 Hetero trimer : IID00254Complex
 Evidence X-RAY 1p22 C Reference
       Region 1p22 C 19-29 disorder
       Region 1p22 C 30-40 order
       Region 1p22 C 41-44 disorder
Seq 30-39 Hetero trimer : P01892
 Evidence X-RAY 3fqn C Reference
       Region 3fqn C 30-33 order
       Region 3fqn C 34-35 disorder
       Region 3fqn C 36-39 order
 Evidence X-RAY 3fqr C Reference
       Region 3fqr C 30-39 order
Seq 131-670 Hetero dimer : IID00100Complex
 Evidence X-RAY 1jpw A Reference
       Region 1jpw A 131-150 disorder
       Region 1jpw A 151-549 order
       Region 1jpw A 550-559 disorder
       Region 1jpw A 560-662 order
       Region 1jpw A 663-670 disorder
 Evidence X-RAY 1jpw B Reference
       Region 1jpw B 131-150 disorder
       Region 1jpw B 151-549 order
       Region 1jpw B 550-559 disorder
       Region 1jpw B 560-662 order
       Region 1jpw B 663-670 disorder
 Evidence X-RAY 1jpw C Reference
       Region 1jpw C 131-150 disorder
       Region 1jpw C 151-549 order
       Region 1jpw C 550-559 disorder
       Region 1jpw C 560-662 order
       Region 1jpw C 663-670 disorder
Seq 133-664 Hetero dimer : IID50010Complex
 Evidence X-RAY 1g3j A Reference
       Region 1g3j A 133-133 disorder
       Region 1g3j A 134-550 order
       Region 1g3j A 551-559 disorder
       Region 1g3j A 560-664 order
 Evidence X-RAY 1g3j C Reference
       Region 1g3j C 133-222 disorder
       Region 1g3j C 223-554 order
       Region 1g3j C 555-557 disorder
       Region 1g3j C 558-664 order
Seq 133-664 Hetero dimer : IID00035Complex
 Evidence X-RAY 1th1 A Reference
       Region 1th1 A 133-144 disorder
       Region 1th1 A 145-552 order
       Region 1th1 A 553-558 disorder
       Region 1th1 A 559-664 order
 Evidence X-RAY 1th1 B Reference
       Region 1th1 B 133-145 disorder
       Region 1th1 B 146-552 order
       Region 1th1 B 553-558 disorder
       Region 1th1 B 559-664 order
Seq 133-665 Hetero dimer : IID50017Complex
 Evidence X-RAY 1qz7 A Reference
       Region 1qz7 A 133-141 disorder
       Region 1qz7 A 142-665 order
Seq 135-663 Hetero dimer : IID00100Complex
 Evidence X-RAY 1jdh A Reference
       Region 1jdh A 135-140 order
       Region 1jdh A 141-150 disorder
       Region 1jdh A 151-548 order
       Region 1jdh A 549-559 disorder
       Region 1jdh A 560-663 order
Seq 138-663 Hetero dimer : IID00001Complex
 Evidence X-RAY 3tx7 A Reference
       Region 3tx7 A 138-147 disorder
       Region 3tx7 A 148-548 order
       Region 3tx7 A 549-558 disorder
       Region 3tx7 A 559-661 order
       Region 3tx7 A 662-663 disorder
Seq 138-686 Hetero trimer : IID00002Complex,IID00100Complex
 Evidence X-RAY 2gl7 A Reference
       Region 2gl7 A 138-141 disorder
       Region 2gl7 A 142-549 order
       Region 2gl7 A 550-559 disorder
       Region 2gl7 A 560-663 order
       Region 2gl7 A 664-686 disorder
 Evidence X-RAY 2gl7 D Reference
       Region 2gl7 D 138-146 disorder
       Region 2gl7 D 147-549 order
       Region 2gl7 D 550-559 disorder
       Region 2gl7 D 560-662 order
       Region 2gl7 D 663-686 disorder
Seq 138-781 Monomer :
 Evidence X-RAY 2z6h A Reference
       Region 2z6h A 138-148 disorder
       Region 2z6h A 149-550 order
       Region 2z6h A 551-560 disorder
       Region 2z6h A 561-691 order
       Region 2z6h A 692-781 disorder
Seq 141-305 Hetero dimer : IID00002Complex
 Evidence X-RAY 3sl9 A Reference
       Region 3sl9 A 141-141 disorder
       Region 3sl9 A 142-305 order
 Evidence X-RAY 3sl9 B Reference
       Region 3sl9 B 141-305 order
 Evidence X-RAY 3sl9 E Reference
       Region 3sl9 E 141-305 order
 Evidence X-RAY 3sl9 G Reference
       Region 3sl9 G 141-147 disorder
       Region 3sl9 G 148-305 order
Seq 141-306 Monomer :
 Evidence X-RAY 3sla A Reference
       Region 3sla A 141-306 order
 Evidence X-RAY 3sla B Reference
       Region 3sla B 141-149 disorder
       Region 3sla B 150-305 order
       Region 3sla B 306-306 disorder
 Evidence X-RAY 3sla C Reference
       Region 3sla C 141-150 disorder
       Region 3sla C 151-162 order
       Region 3sla C 163-164 disorder
       Region 3sla C 165-305 order
       Region 3sla C 306-306 disorder
 Evidence X-RAY 3sla D Reference
       Region 3sla D 141-141 disorder
       Region 3sla D 142-305 order
       Region 3sla D 306-306 disorder
 Evidence X-RAY 3sla E Reference
       Region 3sla E 141-144 disorder
       Region 3sla E 145-306 order
Seq 146-664 Hetero trimer : IID00035Complex,IID00102Complex
 Evidence X-RAY 1t08 A Reference
       Region 1t08 A 146-549 order
       Region 1t08 A 550-558 disorder
       Region 1t08 A 559-664 order
Seq 148-665 Hetero dimer :
 Evidence X-RAY 4djs A Reference
       Region 4djs A 148-549 order
       Region 4djs A 550-560 disorder
       Region 4djs A 561-665 order
Seq 150-663 Hetero dimer : IID00102Complex
 Evidence X-RAY 1luj A Reference
       Region 1luj A 150-549 order
       Region 1luj A 550-562 disorder
       Region 1luj A 563-663 order
Seq 772-781 Hetero dimer : IID50015Complex
 Evidence X-RAY 3diw C Reference
       Region 3diw C 772-772 disorder
       Region 3diw C 773-781 order
 Evidence X-RAY 3diw D Reference
       Region 3diw D 772-772 disorder
       Region 3diw D 773-781 order
SeqProS possible 30-40 Same region of zebra fish homolog (Q90424, 97% identity) is disordered in the free state. Hetero trimer : IID00254Complex
       Region 1p22 C 30-40 order
SeqProS verified 141-149 Hetero trimer : IID00002Complex,IID00100Complex
       Region 2gl7 A 142-549 order
       Region 3sla B 141-149 disorder
SeqProS verified 141-149 Hetero dimer : IID00002Complex
       Region 3sl9 A 142-305 order
       Region 3sl9 B 141-305 order
       Region 3sl9 E 141-305 order
       Region 3sla B 141-149 disorder
SeqProS verified 773-781 Hetero dimer : IID50015Complex
       Region 3diw C 773-781 order
       Region 3diw D 773-781 order
       Region 2z6h A 692-781 disorder
Seqphosphorylation
    23-23 Phosphoserine; by GSK3-beta; alternate
    29-29 Phosphoserine; by GSK3-beta
    33-33 Phosphoserine; by GSK3-beta and HIPK2
    37-37 Phosphoserine; by GSK3-beta and HIPK2
    41-41 Phosphothreonine; by GSK3-beta
    45-45 Phosphoserine
    64-64 Phosphotyrosine; by PTK6
    86-86 Phosphotyrosine; by CSK
    142-142 Phosphotyrosine; by FYN and PTK6
    191-191 Phosphoserine; by CDK5
    246-246 Phosphoserine; by CDK5
    331-331 Phosphotyrosine; by PTK6
    333-333 Phosphotyrosine; by PTK6
    552-552 Phosphoserine
    556-556 Phosphothreonine
    654-654 Phosphotyrosine; by CSK
    675-675 Phosphoserine
Seqacetylation
    2-2 N-acetylalanine
    49-49 N6-acetyllysine
 
Prediction
DICHOT
Disorder 1-82,664-781
Known Domain 83-663
SCOPe RPS-Blast
     4ev8A 159-662 e-147 a.118.1.1 beta-Catenin
SCOP Hmmer
     1g3jA_ 135-664 2.1e-96 a.118.1.1 beta-Catenin
Pfam RPS-Blast
     PF05804 169-544 5e-15 Kinesin-associated protein ...
     PF04826 569-694 6e-04 Armadillo-like
Pfam Hmmer
    PF00514 230-262 1.7e-09 Armadillo/beta-catenin-lik...
    PF00514 351-390 2.5e-11 Armadillo/beta-catenin-lik...
    PF00514 432-473 9.7e-09 Armadillo/beta-catenin-lik...
    PF00514 584-622 1e-09 Armadillo/beta-catenin-like ...