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IID00054  DNA mismatch repair protein Msh6 (Homo sapiens) P52701
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
1360
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 68-201 Monomer :
 Evidence NMR 2gfu A Reference
       Region 2gfu A 68-201 order
       Region 2gfu A 68-86 high_rmsd
       Region 2gfu A 197-201 high_rmsd
Seq 341-1360 Hetero dimer : IID00048Complex
 Evidence X-RAY 2o8b B Reference
       Region 2o8b B 341-361 disorder
       Region 2o8b B 362-550 order
       Region 2o8b B 551-551 disorder
       Region 2o8b B 552-651 order
       Region 2o8b B 652-652 disorder
       Region 2o8b B 653-718 order
       Region 2o8b B 719-727 disorder
       Region 2o8b B 728-933 order
       Region 2o8b B 934-934 disorder
       Region 2o8b B 935-991 order
       Region 2o8b B 992-992 disorder
       Region 2o8b B 993-1098 order
       Region 2o8b B 1099-1104 disorder
       Region 2o8b B 1105-1122 order
       Region 2o8b B 1123-1125 disorder
       Region 2o8b B 1126-1178 order
       Region 2o8b B 1179-1187 disorder
       Region 2o8b B 1188-1270 order
       Region 2o8b B 1271-1283 disorder
       Region 2o8b B 1284-1335 order
       Region 2o8b B 1336-1360 disorder
 Evidence X-RAY 2o8c B Reference
       Region 2o8c B 341-361 disorder
       Region 2o8c B 362-550 order
       Region 2o8c B 551-551 disorder
       Region 2o8c B 552-651 order
       Region 2o8c B 652-652 disorder
       Region 2o8c B 653-718 order
       Region 2o8c B 719-727 disorder
       Region 2o8c B 728-933 order
       Region 2o8c B 934-934 disorder
       Region 2o8c B 935-991 order
       Region 2o8c B 992-992 disorder
       Region 2o8c B 993-1098 order
       Region 2o8c B 1099-1104 disorder
       Region 2o8c B 1105-1124 order
       Region 2o8c B 1125-1125 disorder
       Region 2o8c B 1126-1178 order
       Region 2o8c B 1179-1187 disorder
       Region 2o8c B 1188-1270 order
       Region 2o8c B 1271-1283 disorder
       Region 2o8c B 1284-1335 order
       Region 2o8c B 1336-1360 disorder
 Evidence X-RAY 2o8d B Reference
       Region 2o8d B 341-361 disorder
       Region 2o8d B 362-550 order
       Region 2o8d B 551-551 disorder
       Region 2o8d B 552-651 order
       Region 2o8d B 652-652 disorder
       Region 2o8d B 653-718 order
       Region 2o8d B 719-727 disorder
       Region 2o8d B 728-933 order
       Region 2o8d B 934-934 disorder
       Region 2o8d B 935-991 order
       Region 2o8d B 992-992 disorder
       Region 2o8d B 993-1098 order
       Region 2o8d B 1099-1104 disorder
       Region 2o8d B 1105-1124 order
       Region 2o8d B 1125-1125 disorder
       Region 2o8d B 1126-1178 order
       Region 2o8d B 1179-1187 disorder
       Region 2o8d B 1188-1270 order
       Region 2o8d B 1271-1283 disorder
       Region 2o8d B 1284-1335 order
       Region 2o8d B 1336-1360 disorder
 Evidence X-RAY 2o8e B Reference
       Region 2o8e B 341-361 disorder
       Region 2o8e B 362-550 order
       Region 2o8e B 551-551 disorder
       Region 2o8e B 552-651 order
       Region 2o8e B 652-652 disorder
       Region 2o8e B 653-718 order
       Region 2o8e B 719-727 disorder
       Region 2o8e B 728-933 order
       Region 2o8e B 934-934 disorder
       Region 2o8e B 935-991 order
       Region 2o8e B 992-992 disorder
       Region 2o8e B 993-1100 order
       Region 2o8e B 1101-1103 disorder
       Region 2o8e B 1104-1123 order
       Region 2o8e B 1124-1124 disorder
       Region 2o8e B 1125-1178 order
       Region 2o8e B 1179-1187 disorder
       Region 2o8e B 1188-1270 order
       Region 2o8e B 1271-1283 disorder
       Region 2o8e B 1284-1335 order
       Region 2o8e B 1336-1360 disorder
 Evidence X-RAY 2o8f B Reference
       Region 2o8f B 341-361 disorder
       Region 2o8f B 362-550 order
       Region 2o8f B 551-551 disorder
       Region 2o8f B 552-651 order
       Region 2o8f B 652-652 disorder
       Region 2o8f B 653-718 order
       Region 2o8f B 719-727 disorder
       Region 2o8f B 728-933 order
       Region 2o8f B 934-934 disorder
       Region 2o8f B 935-991 order
       Region 2o8f B 992-992 disorder
       Region 2o8f B 993-1100 order
       Region 2o8f B 1101-1105 disorder
       Region 2o8f B 1106-1124 order
       Region 2o8f B 1125-1125 disorder
       Region 2o8f B 1126-1178 order
       Region 2o8f B 1179-1187 disorder
       Region 2o8f B 1188-1270 order
       Region 2o8f B 1271-1283 disorder
       Region 2o8f B 1284-1335 order
       Region 2o8f B 1336-1360 disorder
Seqphosphorylation
    14-14 Phosphoserine
    41-41 Phosphoserine
    43-43 Phosphoserine
    79-79 Phosphoserine
    91-91 Phosphoserine
    137-137 Phosphoserine
    200-200 Phosphoserine
    219-219 Phosphoserine
    227-227 Phosphoserine
    252-252 Phosphoserine
    254-254 Phosphoserine
    256-256 Phosphoserine
    261-261 Phosphoserine
    269-269 Phosphothreonine
    274-274 Phosphoserine
    275-275 Phosphoserine
    279-279 Phosphoserine
    280-280 Phosphoserine
    309-309 Phosphoserine
    488-488 Phosphothreonine
    830-830 Phosphoserine
    935-935 Phosphoserine
    1010-1010 Phosphothreonine
Seqacetylation
    70-70 N6-acetyllysine
    504-504 N6-acetyllysine
 
Prediction
DICHOT
Disorder 1-67,198-361,1336-1360
Known Domain 68-197,362-1335
SCOPe RPS-Blast
     1h3zA 89-189 2e-21 b.34.9.2 DNA methyltransferase DNMT3B
     1ewqA4 407-521 7e-18 d.75.2.1 DNA repair protein MutS, domain I
     1wb9A1 736-1064 5e-38 a.113.1.1 DNA repair protein MutS, domain III
     1wb9A2 1075-1327 3e-88 c.37.1.12 ABC transporter involved in vitami...
SCOP Hmmer
     1khcA_ 86-209 1.6e-31 b.34.9.2 DNA methyltransf...
     1ewqA4 395-521 1.4e-35 d.75.2.1 DNA repair prot...
     1e3mA1 736-1068 7.8e-65 a.113.1.1 DNA repair pr...
     1e3mA2 1085-1325 3.1e-54 c.37.1.12 ABC transpor...
Pfam RPS-Blast
     PF00855 90-161 7e-12 PWWP domain
     PF04698 198-381 7e-04 Rab effector MyRIP/melanoph...
     PF01624 407-523 2e-15 MutS domain I
     PF05188 538-604 3e-05 MutS domain II
     PF05192 739-1064 2e-21 MutS domain III
     PF00488 1130-1250 4e-05 MutS domain V
Pfam Hmmer
    PF00855 90-183 1e-24 PWWP domain
    PF01624 407-524 3.3e-37 MutS domain I
    PF05188 538-699 3.6e-15 MutS domain II
    PF05192 739-1064 6.8e-39 MutS domain III
    PF00488 1131-1323 2.3e-74 MutS domain V