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IID00061  14-3-3 protein zeta/delta (Homo sapiens) P63104
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
245
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-230 Hetero tetramer : Q9UBF8
 Evidence X-RAY 5nas A Reference
       Region 5nas A 1-230 order
 Evidence X-RAY 5nas B Reference
       Region 5nas B 1-230 order
Seq 1-230 Hetero tetramer :
 Evidence X-RAY 2o02 A Reference
       Region 2o02 A 1-68 order
       Region 2o02 A 69-74 disorder
       Region 2o02 A 75-230 order
 Evidence X-RAY 2o02 B Reference
       Region 2o02 B 1-230 order
Seq 1-230 Hetero tetramer : IID00522Complex
 Evidence X-RAY 5ewz A Reference
       Region 5ewz A 1-1 disorder
       Region 5ewz A 2-230 order
 Evidence X-RAY 5ewz B Reference
       Region 5ewz B 1-69 order
       Region 5ewz B 70-72 disorder
       Region 5ewz B 73-230 order
Seq 1-230 Hetero tetramer : P40818
 Evidence X-RAY 6f09 P Reference
       Region 6f09 P 1-1 disorder
       Region 6f09 P 2-33 order
       Region 6f09 P 34-34 disorder
       Region 6f09 P 35-134 order
       Region 6f09 P 135-135 disorder
       Region 6f09 P 136-230 order
 Evidence X-RAY 6f09 S Reference
       Region 6f09 S 1-1 disorder
       Region 6f09 S 2-135 order
       Region 6f09 S 136-136 disorder
       Region 6f09 S 137-230 order
 Evidence X-RAY 6f09 Q Reference
       Region 6f09 Q 1-1 disorder
       Region 6f09 Q 2-70 order
       Region 6f09 Q 71-71 disorder
       Region 6f09 Q 72-73 order
       Region 6f09 Q 74-75 disorder
       Region 6f09 Q 76-229 order
       Region 6f09 Q 230-230 disorder
 Evidence X-RAY 6f09 R Reference
       Region 6f09 R 1-1 disorder
       Region 6f09 R 2-70 order
       Region 6f09 R 71-71 disorder
       Region 6f09 R 72-201 order
       Region 6f09 R 202-202 disorder
       Region 6f09 R 203-204 order
       Region 6f09 R 205-206 disorder
       Region 6f09 R 207-230 order
Seq 1-230 Hetero trimer : IID00540Complex
 Evidence X-RAY 5d2d A Reference
       Region 5d2d A 1-69 order
       Region 5d2d A 70-70 disorder
       Region 5d2d A 71-230 order
 Evidence X-RAY 5d2d B Reference
       Region 5d2d B 1-69 order
       Region 5d2d B 70-72 disorder
       Region 5d2d B 73-229 order
       Region 5d2d B 230-230 disorder
 Evidence X-RAY 5d3f A Reference
       Region 5d3f A 1-1 disorder
       Region 5d3f A 2-68 order
       Region 5d3f A 69-75 disorder
       Region 5d3f A 76-229 order
       Region 5d3f A 230-230 disorder
 Evidence X-RAY 5d3f B Reference
       Region 5d3f B 1-1 disorder
       Region 5d3f B 2-68 order
       Region 5d3f B 69-72 disorder
       Region 5d3f B 73-229 order
       Region 5d3f B 230-230 disorder
Seq 1-230 Hetero tetramer : IID00198Complex
 Evidence X-RAY 5m37 A Reference
       Region 5m37 A 1-230 order
 Evidence X-RAY 5m37 B Reference
       Region 5m37 B 1-1 disorder
       Region 5m37 B 2-70 order
       Region 5m37 B 71-72 disorder
       Region 5m37 B 73-230 order
Seq 1-230 Hetero tetramer : Q99683
 Evidence X-RAY 6ejl A Reference
       Region 6ejl A 1-69 order
       Region 6ejl A 70-71 disorder
       Region 6ejl A 72-133 order
       Region 6ejl A 134-136 disorder
       Region 6ejl A 137-230 order
 Evidence X-RAY 6ejl B Reference
       Region 6ejl B 1-68 order
       Region 6ejl B 69-72 disorder
       Region 6ejl B 73-228 order
       Region 6ejl B 229-230 disorder
Seq 1-230 Hetero trimer : IID00292Complex
 Evidence X-RAY 4fj3 A Reference
       Region 4fj3 A 1-1 disorder
       Region 4fj3 A 2-69 order
       Region 4fj3 A 70-72 disorder
       Region 4fj3 A 73-203 order
       Region 4fj3 A 204-209 disorder
       Region 4fj3 A 210-230 order
 Evidence X-RAY 4fj3 B Reference
       Region 4fj3 B 1-1 disorder
       Region 4fj3 B 2-69 order
       Region 4fj3 B 70-71 disorder
       Region 4fj3 B 72-133 order
       Region 4fj3 B 134-136 disorder
       Region 4fj3 B 137-203 order
       Region 4fj3 B 204-205 disorder
       Region 4fj3 B 206-230 order
 Evidence X-RAY 4ihl A Reference
       Region 4ihl A 1-230 order
 Evidence X-RAY 4ihl B Reference
       Region 4ihl B 1-70 order
       Region 4ihl B 71-72 disorder
       Region 4ihl B 73-135 order
       Region 4ihl B 136-136 disorder
       Region 4ihl B 137-230 order
Seq 1-230 Hetero tetramer : Q07889
 Evidence X-RAY 6f08 A Reference
       Region 6f08 A 1-68 order
       Region 6f08 A 69-73 disorder
       Region 6f08 A 74-112 order
       Region 6f08 A 113-113 disorder
       Region 6f08 A 114-230 order
 Evidence X-RAY 6f08 B Reference
       Region 6f08 B 1-133 order
       Region 6f08 B 134-135 disorder
       Region 6f08 B 136-205 order
       Region 6f08 B 206-209 disorder
       Region 6f08 B 210-230 order
 Evidence X-RAY 6f08 I Reference
       Region 6f08 I 1-1 disorder
       Region 6f08 I 2-68 order
       Region 6f08 I 69-73 disorder
       Region 6f08 I 74-135 order
       Region 6f08 I 136-136 disorder
       Region 6f08 I 137-230 order
 Evidence X-RAY 6f08 J Reference
       Region 6f08 J 1-69 order
       Region 6f08 J 70-72 disorder
       Region 6f08 J 73-133 order
       Region 6f08 J 134-138 disorder
       Region 6f08 J 139-204 order
       Region 6f08 J 205-210 disorder
       Region 6f08 J 211-230 order
Seq 1-230 Hetero tetramer : IID00522Complex
 Evidence X-RAY 5exa A Reference
       Region 5exa A 1-1 disorder
       Region 5exa A 2-230 order
 Evidence X-RAY 5exa B Reference
       Region 5exa B 1-230 order
Seq 1-230 Hetero tetramer : Q93SQ3
 Evidence X-RAY 5j31 A Reference
       Region 5j31 A 1-206 order
       Region 5j31 A 207-207 disorder
       Region 5j31 A 208-230 order
 Evidence X-RAY 5j31 B Reference
       Region 5j31 B 1-206 order
       Region 5j31 B 207-207 disorder
       Region 5j31 B 208-230 order
 Evidence X-RAY 4n7g A Reference
       Region 4n7g A 1-203 order
       Region 4n7g A 204-204 disorder
       Region 4n7g A 205-230 order
 Evidence X-RAY 4n7y A Reference
       Region 4n7y A 1-230 order
 Evidence X-RAY 4n7y B Reference
       Region 4n7y B 1-70 order
       Region 4n7y B 71-72 disorder
       Region 4n7y B 73-203 order
       Region 4n7y B 204-205 disorder
       Region 4n7y B 206-207 order
       Region 4n7y B 208-210 disorder
       Region 4n7y B 211-230 order
 Evidence X-RAY 4n84 A Reference
       Region 4n84 A 1-206 order
       Region 4n84 A 207-209 disorder
       Region 4n84 A 210-230 order
 Evidence X-RAY 4n84 B Reference
       Region 4n84 B 1-70 order
       Region 4n84 B 71-72 disorder
       Region 4n84 B 73-204 order
       Region 4n84 B 205-205 disorder
       Region 4n84 B 206-206 order
       Region 4n84 B 207-207 disorder
       Region 4n84 B 208-230 order
Seq 1-230 Hetero tetramer : IID00613Complex
 Evidence X-RAY 4zdr A Reference
       Region 4zdr A 1-70 order
       Region 4zdr A 71-72 disorder
       Region 4zdr A 73-230 order
 Evidence X-RAY 4zdr B Reference
       Region 4zdr B 1-70 order
       Region 4zdr B 71-72 disorder
       Region 4zdr B 73-208 order
       Region 4zdr B 209-209 disorder
       Region 4zdr B 210-230 order
Seq 1-230 Hetero octamer : Q96RR4
 Evidence X-RAY 6eww A Reference
       Region 6eww A 1-69 order
       Region 6eww A 70-73 disorder
       Region 6eww A 74-202 order
       Region 6eww A 203-211 disorder
       Region 6eww A 212-229 order
       Region 6eww A 230-230 disorder
 Evidence X-RAY 6eww B Reference
       Region 6eww B 1-68 order
       Region 6eww B 69-72 disorder
       Region 6eww B 73-204 order
       Region 6eww B 205-207 disorder
       Region 6eww B 208-229 order
       Region 6eww B 230-230 disorder
 Evidence X-RAY 6eww C Reference
       Region 6eww C 1-69 order
       Region 6eww C 70-74 disorder
       Region 6eww C 75-133 order
       Region 6eww C 134-137 disorder
       Region 6eww C 138-230 order
 Evidence X-RAY 6eww D Reference
       Region 6eww D 1-1 disorder
       Region 6eww D 2-67 order
       Region 6eww D 68-76 disorder
       Region 6eww D 77-229 order
       Region 6eww D 230-230 disorder
Seq 1-245 Hetero dimer : Q5SZL8
 Evidence X-RAY 5ulo A Reference
       Region 5ulo A 1-68 order
       Region 5ulo A 69-71 disorder
       Region 5ulo A 72-134 order
       Region 5ulo A 135-135 disorder
       Region 5ulo A 136-229 order
       Region 5ulo A 230-245 disorder
 Evidence X-RAY 5ulo B Reference
       Region 5ulo B 1-134 order
       Region 5ulo B 135-135 disorder
       Region 5ulo B 136-229 order
       Region 5ulo B 230-245 disorder
Seq 1-245 Hetero tetramer : IID50013Complex
 Evidence X-RAY 1ib1 C Reference
       Region 1ib1 C 1-1 disorder
       Region 1ib1 C 2-228 order
       Region 1ib1 C 229-245 disorder
 Evidence X-RAY 1ib1 D Reference
       Region 1ib1 D 1-1 disorder
       Region 1ib1 D 2-228 order
       Region 1ib1 D 229-245 disorder
Seq 1-245 Hetero tetramer : P0DOJ7
 Evidence X-RAY 1qjb A Reference
       Region 1qjb A 1-68 order
       Region 1qjb A 69-72 disorder
       Region 1qjb A 73-232 order
       Region 1qjb A 233-245 disorder
 Evidence X-RAY 1qjb B Reference
       Region 1qjb B 1-232 order
       Region 1qjb B 233-245 disorder
Seq 1-245 Hetero trimer : IID00066Complex
 Evidence X-RAY 2wh0 A Reference
       Region 2wh0 A 1-1 disorder
       Region 2wh0 A 2-70 order
       Region 2wh0 A 71-71 disorder
       Region 2wh0 A 72-203 order
       Region 2wh0 A 204-209 disorder
       Region 2wh0 A 210-229 order
       Region 2wh0 A 230-245 disorder
 Evidence X-RAY 2wh0 B Reference
       Region 2wh0 B 1-1 disorder
       Region 2wh0 B 2-228 order
       Region 2wh0 B 229-245 disorder
 Evidence X-RAY 2wh0 C Reference
       Region 2wh0 C 1-3 disorder
       Region 2wh0 C 4-229 order
       Region 2wh0 C 230-245 disorder
 Evidence X-RAY 2wh0 D Reference
       Region 2wh0 D 1-1 disorder
       Region 2wh0 D 2-66 order
       Region 2wh0 D 67-71 disorder
       Region 2wh0 D 72-204 order
       Region 2wh0 D 205-205 disorder
       Region 2wh0 D 206-229 order
       Region 2wh0 D 230-245 disorder
Seq 1-245 Hetero tetramer :
 Evidence X-RAY 1qja A Reference
       Region 1qja A 1-66 order
       Region 1qja A 67-76 disorder
       Region 1qja A 77-133 order
       Region 1qja A 134-136 disorder
       Region 1qja A 137-230 order
       Region 1qja A 231-245 disorder
 Evidence X-RAY 1qja B Reference
       Region 1qja B 1-133 order
       Region 1qja B 134-137 disorder
       Region 1qja B 138-229 order
       Region 1qja B 230-245 disorder
Seq 1-245 Hetero tetramer : Q9Y3M2
 Evidence X-RAY 4wrq A Reference
       Region 4wrq A 1-66 order
       Region 4wrq A 67-76 disorder
       Region 4wrq A 77-230 order
       Region 4wrq A 231-245 disorder
 Evidence X-RAY 4wrq B Reference
       Region 4wrq B 1-229 order
       Region 4wrq B 230-245 disorder
Seq 1-245 Hetero tetramer : IID00292Complex
 Evidence X-RAY 3cu8 A Reference
       Region 3cu8 A 1-1 disorder
       Region 3cu8 A 2-230 order
       Region 3cu8 A 231-245 disorder
 Evidence X-RAY 3cu8 B Reference
       Region 3cu8 B 1-70 order
       Region 3cu8 B 71-72 disorder
       Region 3cu8 B 73-230 order
       Region 3cu8 B 231-245 disorder
 Evidence X-RAY 3nkx A Reference
       Region 3nkx A 1-1 disorder
       Region 3nkx A 2-230 order
       Region 3nkx A 231-245 disorder
 Evidence X-RAY 3nkx B Reference
       Region 3nkx B 1-70 order
       Region 3nkx B 71-72 disorder
       Region 3nkx B 73-230 order
       Region 3nkx B 231-245 disorder
Seq 1-245 Hetero dimer : IID00615Complex
 Evidence X-RAY 4hkc A Reference
       Region 4hkc A 1-1 disorder
       Region 4hkc A 2-230 order
       Region 4hkc A 231-245 disorder
Seq 1-245 Hetero tetramer : IID50013Complex
 Evidence X-RAY 1ib1 A Reference
       Region 1ib1 A 1-1 disorder
       Region 1ib1 A 2-228 order
       Region 1ib1 A 229-245 disorder
 Evidence X-RAY 1ib1 B Reference
       Region 1ib1 B 1-1 disorder
       Region 1ib1 B 2-228 order
       Region 1ib1 B 229-245 disorder
Seq 1-245 Hetero tetramer : IID00062Complex
 Evidence X-RAY 2c1j A Reference
       Region 2c1j A 1-230 order
       Region 2c1j A 231-245 disorder
 Evidence X-RAY 2c1j B Reference
       Region 2c1j B 1-230 order
       Region 2c1j B 231-245 disorder
Seq 1-245 Homo dimer :
 Evidence X-RAY 5jm4 A Reference
       Region 5jm4 A 1-1 disorder
       Region 5jm4 A 2-70 order
       Region 5jm4 A 71-71 disorder
       Region 5jm4 A 72-229 order
 Evidence X-RAY 5jm4 B Reference
       Region 5jm4 B 1-207 order
       Region 5jm4 B 208-208 disorder
       Region 5jm4 B 209-229 order
 Evidence X-RAY 3rdh A Reference
       Region 3rdh A 1-230 order
       Region 3rdh A 231-245 disorder
 Evidence X-RAY 3rdh D Reference
       Region 3rdh D 1-230 order
       Region 3rdh D 231-245 disorder
 Evidence X-RAY 3rdh B Reference
       Region 3rdh B 1-230 order
       Region 3rdh B 231-245 disorder
 Evidence X-RAY 3rdh C Reference
       Region 3rdh C 1-230 order
       Region 3rdh C 231-245 disorder
Seq 1-245 Hetero dimer : P61587
 Evidence X-RAY 4bg6 A Reference
       Region 4bg6 A 1-69 order
       Region 4bg6 A 70-72 disorder
       Region 4bg6 A 73-231 order
       Region 4bg6 A 232-245 disorder
 Evidence X-RAY 4bg6 B Reference
       Region 4bg6 B 1-1 disorder
       Region 4bg6 B 2-230 order
       Region 4bg6 B 231-245 disorder
Seq 1-245 Hetero tetramer : IID00613Complex
 Evidence X-RAY 5wxn A Reference
       Region 5wxn A 1-230 order
       Region 5wxn A 231-245 disorder
 Evidence X-RAY 5wxn B Reference
       Region 5wxn B 1-230 order
       Region 5wxn B 231-245 disorder
Seq 1-245 Hetero dimer : IID00062Complex
 Evidence X-RAY 2c1n A Reference
       Region 2c1n A 1-133 order
       Region 2c1n A 134-138 disorder
       Region 2c1n A 139-230 order
       Region 2c1n A 231-245 disorder
 Evidence X-RAY 2c1n B Reference
       Region 2c1n B 1-133 order
       Region 2c1n B 134-138 disorder
       Region 2c1n B 139-230 order
       Region 2c1n B 231-245 disorder
Seq 2-230 Hetero tetramer : IID00198Complex
 Evidence X-RAY 5m35 A Reference
       Region 5m35 A 2-204 order
       Region 5m35 A 205-205 disorder
       Region 5m35 A 206-230 order
 Evidence X-RAY 5m35 B Reference
       Region 5m35 B 2-70 order
       Region 5m35 B 71-72 disorder
       Region 5m35 B 73-204 order
       Region 5m35 B 205-208 disorder
       Region 5m35 B 209-230 order
Seq 2-230 Hetero trimer : IID00198Complex
 Evidence X-RAY 5m36 A Reference
       Region 5m36 A 2-69 order
       Region 5m36 A 70-72 disorder
       Region 5m36 A 73-204 order
       Region 5m36 A 205-209 disorder
       Region 5m36 A 210-230 order
 Evidence X-RAY 5m36 B Reference
       Region 5m36 B 2-67 order
       Region 5m36 B 68-70 disorder
       Region 5m36 B 71-204 order
       Region 5m36 B 205-210 disorder
       Region 5m36 B 211-229 order
       Region 5m36 B 230-230 disorder
Seqphosphorylation
    58-58 Phosphoserine; by PKA and PKB/AKT1
    184-184 Phosphoserine; by MAPK8
    207-207 Phosphoserine
    210-210 Phosphoserine
    232-232 Phosphothreonine; by CK1
Seqacetylation
    1-1 N-acetylmethionine
    3-3 N6-acetyllysine
    68-68 N6-acetyllysine
 
Prediction
DICHOT
Disorder 231-245
Known Domain 1-230
SCOPe RPS-Blast
     3mhrA1 1-229 6e-61 a.118.7.1 14-3-3 domain containing protein cgd7_...
SCOP Hmmer
     1qjbA_ 1-231 2.5e-110 a.118.7.1 14-3-3 domain c...
Pfam RPS-Blast
     PF00244 10-229 4e-41 14-3-3 protein
Pfam Hmmer
    PF00244 9-229 6.5e-114 14-3-3 protein