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IID00066  Protein kinase C epsilon type (Homo sapiens) Q02156
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
737
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 149-164 Hetero tetramer : P41743
 Evidence X-RAY 5lih F Reference
       Region 5lih F 149-149 disorder
       Region 5lih F 150-162 order
       Region 5lih F 163-164 disorder
 Evidence X-RAY 5lih G Reference
       Region 5lih G 149-152 disorder
       Region 5lih G 153-162 order
       Region 5lih G 163-164 disorder
Seq 342-372 Hetero trimer : IID00061Complex
 Evidence X-RAY 2wh0 Q Reference
       Region 2wh0 Q 342-342 disorder
       Region 2wh0 Q 343-347 order
       Region 2wh0 Q 348-364 disorder
       Region 2wh0 Q 365-372 order
 Evidence X-RAY 2wh0 R Reference
       Region 2wh0 R 342-342 disorder
       Region 2wh0 R 343-347 order
       Region 2wh0 R 348-365 disorder
       Region 2wh0 R 366-369 order
       Region 2wh0 R 370-372 disorder
SeqProS possible 343-347,365-372 14-3-3 binding motif Hetero trimer : IID00061Complex
       Region 2wh0 Q 343-347 order
       Region 2wh0 R 343-347 order
       Region 2wh0 Q 365-372 order
       Region 2wh0 R 366-369 order
Seqphosphorylation
    62-62 Phosphoserine
    228-228 Phosphothreonine
    234-234 Phosphoserine
    309-309 Phosphothreonine
    316-316 Phosphoserine
    329-329 Phosphoserine
    337-337 Phosphoserine
    346-346 Phosphoserine; by GSK3-beta
    349-349 Phosphothreonine
    350-350 Phosphoserine; by MAPK11 and MAPK14
    368-368 Phosphoserine; by autocatalysis
    388-388 Phosphoserine
    566-566 Phosphothreonine; by PDPK1
    703-703 Phosphothreonine; by autocatalysis
    710-710 Phosphothreonine
    729-729 Phosphoserine; by autocatalysis
 
Prediction
DICHOT
Disorder 137-167,238-242
Known Domain 1-136,168-237,243-737
SCOPe RPS-Blast
     2fk9A1 1-132 2e-37 b.7.1.0 automated matches
     2yuuA1 161-226 2e-27 g.49.1.0 automated matches
     4fkdA1 243-292 9e-23 g.49.1.1 Beta-chimaerin, middle domain
     1o6lA 402-733 e-172 d.144.1.7 3-phosphoinositide dependent protein k...
SCOP Hmmer
     1gmiA_ 3-132 1.1e-30 b.7.1.1 Domain from cytoso...
     1r79A_ 148-221 2.4e-21 Cysteine-rich domain
     1r79A_ 236-295 3e-22 Cysteine-rich domain
     1o6lA_ 405-717 5.4e-94 d.144.1.7 3-phosphoinosi...
Pfam RPS-Blast
     PF00130 170-220 1e-10 Phorbol esters/diacylglycer...
     PF00130 243-293 1e-11 Phorbol esters/diacylglycer...
     PF06293 483-555 5e-05 Lipopolysaccharide kinase (...
     PF14531 529-608 7e-05 Kinase-like
     PF00433 697-730 4e-05 Protein kinase C terminal d...
Pfam Hmmer
    PF00168 7-116 3.8e-16 C2 domain
    PF00130 170-221 3e-19 Phorbol esters/diacylglycero...
    PF00130 243-294 4.4e-20 Phorbol esters/diacylglyce...
    PF00069 409-668 1.1e-68 Protein kinase domain
    PF00433 690-730 3.8e-12 Protein kinase C terminal ...