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IID00067
 UniprotQ02548
ProteinPaired box protein Pax-5
GenePAX5
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
391
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-149 Hetero dimer : IID50005Complex
 Evidence X-RAY 1k78 I Reference
       Region 1k78 I 1-83 disorder
       Region 1k78 I 84-141 order
       Region 1k78 I 142-149 disorder
 Evidence X-RAY 1k78 A Reference
       Region 1k78 A 1-18 disorder
       Region 1k78 A 19-142 order
       Region 1k78 A 143-149 disorder
Seq 1-149 Hetero dimer : IID50005Complex
 Evidence X-RAY 1k78 E Reference
       Region 1k78 E 1-18 disorder
       Region 1k78 E 19-142 order
       Region 1k78 E 143-149 disorder
 Evidence X-RAY 1mdm A Reference
       Region 1mdm A 1-18 disorder
       Region 1mdm A 19-142 order
       Region 1mdm A 143-149 disorder
 
Prediction
NeProc
Disorder 1-2,146-391
Order 3-145
ProS 1-2,146-149,155-159,176-187,198-206,213-276,354-359,368-371,387-391
AlphaFold
Disorder 1-16,145-178,188-227,241-391
Order 17-144,179-187,228-240
Pfam Hmmer
PF00292 16-140 1.1e-90
SEG 157-189 ,369-388
Function
Function in SwissProt
May play an important role in B-cell differentiation as well as neural development and spermatogenesis. Involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene.