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IID00087  BCL-6 corepressor (Homo sapiens) Q6W2J9
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
1755
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 498-514 Hetero tetramer : IID00372Complex
 Evidence X-RAY 3bim K Reference
       Region 3bim K 498-514 order
 Evidence X-RAY 3bim L Reference
       Region 3bim L 498-498 disorder
       Region 3bim L 499-514 order
 Evidence X-RAY 3bim O Reference
       Region 3bim O 498-514 order
 Evidence X-RAY 3bim P Reference
       Region 3bim P 498-514 order
 Evidence X-RAY 3bim I Reference
       Region 3bim I 498-514 order
 Evidence X-RAY 3bim J Reference
       Region 3bim J 498-514 order
 Evidence X-RAY 3bim M Reference
       Region 3bim M 498-514 order
 Evidence X-RAY 3bim N Reference
       Region 3bim N 498-498 disorder
       Region 3bim N 499-514 order
Seq 1634-1748 Hetero dimer : IID00621Complex
 Evidence X-RAY 4hpl A Reference
       Region 4hpl A 1634-1635 disorder
       Region 4hpl A 1636-1748 order
Seq 1634-1748 Monomer :
 Evidence NMR 2n1l A Reference
       Region 2n1l A 1634-1748 order
SeqProS possible 498-514 With the exception of the ankyrin region, BCOR is described to be disordered (PubMed=18280243). Hetero tetramer : IID00372Complex
       Region 3bim I 498-514 order
       Region 3bim J 498-514 order
       Region 3bim K 498-514 order
       Region 3bim L 499-514 order
       Region 3bim M 498-514 order
       Region 3bim N 499-514 order
       Region 3bim O 498-514 order
       Region 3bim P 498-514 order
SeqProS possible 1636-1748 With the exception of the ankyrin region, BCOR is described to be disordered (PubMed=18280243). Hetero dimer : IID00621Complex
       Region 4hpl A 1636-1748 order
Seqphosphorylation
    336-336 Phosphoserine
    340-340 Phosphoserine
    365-365 Phosphoserine
    367-367 Phosphoserine
    423-423 Phosphoserine
    1127-1127 Phosphoserine
    1139-1139 Phosphoserine
    1290-1290 Phosphoserine
    1345-1345 Phosphoserine
    1410-1410 Phosphoserine
Seqacetylation
    392-392 N6-acetyllysine
 
Prediction
DICHOT
Disorder 1-53,94-184,258-440,471-650,733-1460,1580-1635,1749-1755
Known Domain 1461-1579,1636-1748
Cryptic Domain 54-93,185-257,441-470,651-732
SCOPe RPS-Blast
     3c5rA2 1461-1579 3e-46 d.211.1.1 26S proteasome non-ATPase regulato...
SCOP Hmmer
     1ot8A_ 1461-1568 2.2e-31 d.211.1.1 26S proteaso...
Pfam RPS-Blast
     PF12851 243-749 5e-04 Oxygenase domain of the 2OG...
     PF15808 1336-1382 3e-09 BCL-6 co-repressor, non-a...
     PF13857 1458-1504 1e-04 Ankyrin repeats (many cop...
     PF00023 1497-1524 1e-04 Ankyrin repeat
     PF13857 1516-1565 1e-11 Ankyrin repeats (many cop...
     PF16553 1634-1746 3e-48 BCORL-PCGF1-binding domai...
Pfam Hmmer
    PF15808 1202-1414 2.4e-77 BCL-6 co-repressor, non-...
    PF12796 1467-1558 8e-19 Ankyrin repeats (3 copies)
    PF16553 1634-1746 1.9e-55 BCORL-PCGF1-binding doma...