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IID00094
 UniprotQ92973
ProteinTransportin-1
GeneTNPO1
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
898
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 9-343,376-898 Hetero hexamer : IID00119Complex
 Evidence X-RAY 2h4m B Reference
       Region 2h4m B 9-13 disorder
       Region 2h4m B 14-44 order
       Region 2h4m B 45-51 disorder
       Region 2h4m B 52-63 order
       Region 2h4m B 64-66 disorder
       Region 2h4m B 67-83 order
       Region 2h4m B 84-87 disorder
       Region 2h4m B 88-166 order
       Region 2h4m B 167-178 disorder
       Region 2h4m B 179-327 order
       Region 2h4m B 328-343 disorder
       Region 2h4m B 376-376 disorder
       Region 2h4m B 377-898 order
 Evidence X-RAY 2h4m A Reference
       Region 2h4m A 9-13 disorder
       Region 2h4m A 14-44 order
       Region 2h4m A 45-51 disorder
       Region 2h4m A 52-85 order
       Region 2h4m A 86-87 disorder
       Region 2h4m A 88-327 order
       Region 2h4m A 328-343 disorder
       Region 2h4m A 376-376 disorder
       Region 2h4m A 377-898 order
Seq 9-898 Hetero dimer : IID00075Complex
 Evidence X-RAY 2z5n A Reference
       Region 2z5n A 9-12 disorder
       Region 2z5n A 13-327 order
       Region 2z5n A 328-373 disorder
       Region 2z5n A 374-898 order
Seq 9-898 Hetero dimer : IID00451Complex
 Evidence X-RAY 4fq3 A Reference
       Region 4fq3 A 9-13 disorder
       Region 4fq3 A 14-327 order
       Region 4fq3 A 328-378 disorder
       Region 4fq3 A 379-898 order
Seq 9-331,375-898 Hetero trimer : IID00451Complex
 Evidence X-RAY 4fdd A Reference
       Region 4fdd A 9-12 disorder
       Region 4fdd A 13-328 order
       Region 4fdd A 329-331 disorder
       Region 4fdd A 375-378 disorder
       Region 4fdd A 379-898 order
Seq 9-331,375-898 Hetero trimer : IID00062Complex
 Evidence X-RAY 5j3v B Reference
       Region 5j3v B 9-33 disorder
       Region 5j3v B 34-51 order
       Region 5j3v B 52-54 disorder
       Region 5j3v B 55-328 order
       Region 5j3v B 329-331 disorder
       Region 5j3v B 375-376 disorder
       Region 5j3v B 377-897 order
       Region 5j3v B 898-898 disorder
Seq 9-331,375-898 Hetero trimer : IID00567Complex
 Evidence X-RAY 4oo6 A Reference
       Region 4oo6 A 9-12 disorder
       Region 4oo6 A 13-327 order
       Region 4oo6 A 328-331 disorder
       Region 4oo6 A 375-377 disorder
       Region 4oo6 A 378-898 order
Seq 9-898 Hetero dimer : IID00225Complex
 Evidence X-RAY 2z5k A Reference
       Region 2z5k A 9-12 disorder
       Region 2z5k A 13-327 order
       Region 2z5k A 328-373 disorder
       Region 2z5k A 374-898 order
 Evidence X-RAY 2z5m A Reference
       Region 2z5m A 9-12 disorder
       Region 2z5m A 13-327 order
       Region 2z5m A 328-373 disorder
       Region 2z5m A 374-898 order
Seq 9-898 Monomer :
 Evidence X-RAY 2qmr A Reference
       Region 2qmr A 9-13 disorder
       Region 2qmr A 14-327 order
       Region 2qmr A 328-377 disorder
       Region 2qmr A 378-898 order
 Evidence X-RAY 2qmr B Reference
       Region 2qmr B 9-37 disorder
       Region 2qmr B 38-166 order
       Region 2qmr B 167-174 disorder
       Region 2qmr B 175-327 order
       Region 2qmr B 328-379 disorder
       Region 2qmr B 380-898 order
 Evidence X-RAY 2qmr C Reference
       Region 2qmr C 9-12 disorder
       Region 2qmr C 13-29 order
       Region 2qmr C 30-37 disorder
       Region 2qmr C 38-166 order
       Region 2qmr C 167-171 disorder
       Region 2qmr C 172-327 order
       Region 2qmr C 328-376 disorder
       Region 2qmr C 377-898 order
 Evidence X-RAY 2qmr D Reference
       Region 2qmr D 9-14 disorder
       Region 2qmr D 15-327 order
       Region 2qmr D 328-376 disorder
       Region 2qmr D 377-898 order
 Evidence X-RAY 2z5j A Reference
       Region 2z5j A 9-12 disorder
       Region 2z5j A 13-327 order
       Region 2z5j A 328-378 disorder
       Region 2z5j A 379-898 order
 Evidence X-RAY 2z5o A Reference
       Region 2z5o A 9-13 disorder
       Region 2z5o A 14-327 order
       Region 2z5o A 328-378 disorder
       Region 2z5o A 379-898 order
Seq 9-898 Hetero dimer : IID00162Complex
 Evidence X-RAY 1qbk B Reference
       Region 1qbk B 9-10 disorder
       Region 1qbk B 11-174 order
       Region 1qbk B 175-177 disorder
       Region 1qbk B 178-360 order
       Region 1qbk B 361-365 disorder
       Region 1qbk B 366-898 order
Seq 9-343,375-898 Hetero trimer : G0SFC3
 Evidence X-RAY 5tqc A Reference
       Region 5tqc A 9-11 disorder
       Region 5tqc A 12-328 order
       Region 5tqc A 329-343 disorder
       Region 5tqc A 375-375 disorder
       Region 5tqc A 376-898 order
Seq 9-331,375-898 Hetero trimer : IID00062Complex
 Evidence X-RAY 5j3v A Reference
       Region 5j3v A 9-15 disorder
       Region 5j3v A 16-329 order
       Region 5j3v A 330-331 disorder
       Region 5j3v A 375-375 disorder
       Region 5j3v A 376-896 order
       Region 5j3v A 897-898 disorder
Seq 9-331,375-898 Hetero trimer : IID50171Complex
 Evidence X-RAY 4jlq A Reference
       Region 4jlq A 9-11 disorder
       Region 4jlq A 12-328 order
       Region 4jlq A 329-331 disorder
       Region 4jlq A 375-375 disorder
       Region 4jlq A 376-898 order
Seq 9-331,375-898 Hetero trimer : IID00152Complex
 Evidence X-RAY 2ot8 B Reference
       Region 2ot8 B 9-17 disorder
       Region 2ot8 B 18-49 order
       Region 2ot8 B 50-54 disorder
       Region 2ot8 B 55-66 order
       Region 2ot8 B 67-72 disorder
       Region 2ot8 B 73-169 order
       Region 2ot8 B 170-178 disorder
       Region 2ot8 B 179-327 order
       Region 2ot8 B 328-331 disorder
       Region 2ot8 B 375-375 disorder
       Region 2ot8 B 376-898 order
Seq 9-331,375-898 Hetero trimer : IID00152Complex
 Evidence X-RAY 2ot8 A Reference
       Region 2ot8 A 9-17 disorder
       Region 2ot8 A 18-31 order
       Region 2ot8 A 32-34 disorder
       Region 2ot8 A 35-51 order
       Region 2ot8 A 52-53 disorder
       Region 2ot8 A 54-64 order
       Region 2ot8 A 65-69 disorder
       Region 2ot8 A 70-327 order
       Region 2ot8 A 328-331 disorder
       Region 2ot8 A 375-898 order
SeqProS verified 328-360,366-372 Hetero dimer : IID00162Complex
       Region 1qbk B 178-360 order
       Region 1qbk B 366-898 order
       Region 2z5j A 328-378 disorder
Seqacetylation
    1-1 N-acetylmethionine
 
Prediction
NeProc
Disorder 1-9,329-377
Order 10-65,70-328,378-898
ProS 1-9,329-377
AlphaFold
Disorder 1-12,327-329,357-379
Order 13-326,330-356,380-898
Pfam Hmmer
PF03810 41-109 1e-16
PF02985 218-254 0.00019
PF02985 400-436 5.6e-05
PF02985 441-477 2.4e-05
PF02985 670-706 0.00041
SEG 358-376 ,401-418
Function
Function in SwissProt
(Microbial infection) In case of HIV-1 infection, binds and mediates the nuclear import of HIV-1 Rev.