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IID00099
 UniprotQ99741
ProteinCell division control protein 6 homolog
GeneCDC6
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
560
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seqdisorder 70-90
 Evidence X-RAY 4i5n E Reference
       Region 4i5n E 70-90 disorder
Seqdisorder 70-90
 Evidence X-RAY 4i5l E Reference
       Region 4i5l E 70-90 disorder
Seqdisorder 70-90
 Evidence X-RAY 4i5n B Reference
       Region 4i5n B 70-90 disorder
Seqdisorder 70-90
 Evidence X-RAY 4i5l B Reference
       Region 4i5l B 70-90 disorder
Seq 71-100 Hetero trimer : IID00032Complex,IID00034Complex
 Evidence X-RAY 2cci F Reference
       Region 2cci F 71-77 order
       Region 2cci F 78-88 disorder
       Region 2cci F 89-100 order
 Evidence X-RAY 2cci I Reference
       Region 2cci I 71-72 disorder
       Region 2cci I 73-77 order
       Region 2cci I 78-89 disorder
       Region 2cci I 90-98 order
       Region 2cci I 99-100 disorder
Seq 89-100 Hetero trimer : IID00032Complex
 Evidence X-RAY 2cch E Reference
       Region 2cch E 89-100 order
 Evidence X-RAY 2cch F Reference
       Region 2cch F 89-100 order
Seqphosphorylation
    419-419 Phosphoserine
    127-127 Phosphoserine
    106-106 Phosphoserine
    74-74 Phosphoserine
    67-67 Phosphothreonine
    54-54 Phosphoserine
    45-45 Phosphoserine
 
Prediction
NeProc
Disorder 1-153,406-426
Order 154-405,427-560
ProS 4-21,54-67
AlphaFold
Disorder 1-154,252-261,274-274,327-327,330-332,334-335,363-365,409-427,443-456,557-560
Order 155-251,262-273,275-326,328-329,333-333,336-362,366-408,428-442,457-556
Pfam Hmmer
PF00004 197-403 8.5e-14
SEG 533-542
Function
Function in SwissProt
Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.