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IID00120  E3 ubiquitin-protein ligase SIAH1 (Homo sapiens) Q8IUQ4
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
282
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 90-282 Hetero dimer : IID50260Complex
 Evidence X-RAY 4i7b A Reference
       Region 4i7b A 90-90 disorder
       Region 4i7b A 91-197 order
       Region 4i7b A 198-200 disorder
       Region 4i7b A 201-282 order
 Evidence X-RAY 4i7b C Reference
       Region 4i7b C 90-93 disorder
       Region 4i7b C 94-197 order
       Region 4i7b C 198-199 disorder
       Region 4i7b C 200-282 order
 Evidence X-RAY 4i7c A Reference
       Region 4i7c A 90-90 disorder
       Region 4i7c A 91-198 order
       Region 4i7c A 199-202 disorder
       Region 4i7c A 203-282 order
 Evidence X-RAY 4i7c C Reference
       Region 4i7c C 90-90 disorder
       Region 4i7c C 91-198 order
       Region 4i7c C 199-200 disorder
       Region 4i7c C 201-282 order
 Evidence X-RAY 4i7d A Reference
       Region 4i7d A 90-90 disorder
       Region 4i7d A 91-197 order
       Region 4i7d A 198-202 disorder
       Region 4i7d A 203-282 order
 Evidence X-RAY 4i7d C Reference
       Region 4i7d C 90-91 disorder
       Region 4i7d C 92-198 order
       Region 4i7d C 199-200 disorder
       Region 4i7d C 201-282 order
Seq 90-282 Hetero tetramer : IID00125Complex
 Evidence X-RAY 2a25 A Reference
       Region 2a25 A 90-124 disorder
       Region 2a25 A 125-131 order
       Region 2a25 A 132-133 disorder
       Region 2a25 A 134-171 order
       Region 2a25 A 172-175 disorder
       Region 2a25 A 176-196 order
       Region 2a25 A 197-202 disorder
       Region 2a25 A 203-282 order
Seq 91-282 Homo dimer :
 Evidence X-RAY 4c9z A Reference
       Region 4c9z A 91-282 order
 Evidence X-RAY 4c9z B Reference
       Region 4c9z B 91-94 disorder
       Region 4c9z B 95-282 order
 Evidence X-RAY 4ca1 A Reference
       Region 4ca1 A 91-198 order
       Region 4ca1 A 199-201 disorder
       Region 4ca1 A 202-282 order
 Evidence X-RAY 4ca1 B Reference
       Region 4ca1 B 91-197 order
       Region 4ca1 B 198-199 disorder
       Region 4ca1 B 200-282 order
Seq 91-282 Hetero dimer : O94966
 Evidence X-RAY 4x3g A Reference
       Region 4x3g A 91-131 order
       Region 4x3g A 132-132 disorder
       Region 4x3g A 133-199 order
       Region 4x3g A 200-202 disorder
       Region 4x3g A 203-282 order
 Evidence X-RAY 4x3g B Reference
       Region 4x3g B 91-92 disorder
       Region 4x3g B 93-282 order
Seq 93-282 Hetero dimer : IID00007Complex
 Evidence X-RAY 5wzz A Reference
       Region 5wzz A 93-282 order
 Evidence X-RAY 5wzz B Reference
       Region 5wzz B 93-282 order
 Evidence X-RAY 5wzz C Reference
       Region 5wzz C 93-282 order
 Evidence X-RAY 5wzz D Reference
       Region 5wzz D 93-282 order
Seqphosphorylation
    19-19 Phosphoserine; by ATM and ATR
 
Prediction
DICHOT
Disorder 1-18
Known Domain 19-282
SCOPe RPS-Blast
     3lrqA1 34-85 2e-04 g.44.1.0 automated matches
     4ca1A 91-282 3e-49 b.8.1.2 SIAH, seven in absentia homolog
SCOP Hmmer
     1t1hA_ 34-96 2.1e-09 RING/U-box
     1k2fA_ 93-281 1.9e-66 b.8.1.2 SIAH, seven in ab...
Pfam RPS-Blast
     PF03145 82-278 7e-43 Seven in absentia protein fa...
Pfam Hmmer
    PF03145 82-278 1.1e-92 Seven in absentia protein f...