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IID00129  Alpha-actinin-4 (Homo sapiens) O43707
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
911
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 47-271 Monomer :
 Evidence X-RAY 2r0o A Reference
       Region 2r0o A 47-271 order
 Evidence X-RAY 2r0o B Reference
       Region 2r0o B 47-271 order
Seq 519-645 Monomer :
 Evidence NMR 1wlx A Reference
       Region 1wlx A 519-645 order
       Region 1wlx A 606-606 high_rmsd
Seq 734-757 Hetero dimer : P18206
 Evidence X-RAY 1ydi B Reference
       Region 1ydi B 734-757 order
Seqphosphorylation
    249-249 Phosphothreonine
Seqacetylation
    114-114 N6-acetyllysine
    592-592 N6-acetyllysine
    625-625 N6-acetyllysine
    779-779 N6-acetyllysine
    859-859 N6-acetyllysine
 
Prediction
DICHOT
Disorder 1-43
Known Domain 44-911
SCOPe RPS-Blast
     1wkuA1 47-160 4e-61 a.40.1.0 automated matches
     1bkrA 164-269 1e-57 a.40.1.1 Actin binding domain of plectin
     1hciA1 286-408 3e-34 a.7.1.1 alpha-actinin
     1quuA1 403-523 2e-30 a.7.1.1 alpha-actinin
     1quuA2 524-647 3e-36 a.7.1.1 alpha-actinin
     1hciA4 645-758 1e-31 a.7.1.1 alpha-actinin
     2n8zA1 762-911 5e-50 a.39.1.0 automated matches
SCOP Hmmer
     1rt8A_ 34-266 6.1e-86 a.40.1.1 Actin binding do...
     1hciA1 286-408 1.7e-36 a.7.1.1 alpha-actinin
     1hciA4 409-517 2.7e-26 a.7.1.1 alpha-actinin
     1hciA1 522-640 8.9e-31 a.7.1.1 alpha-actinin
     1hciA4 646-758 1e-24 a.7.1.1 alpha-actinin
     1ncxA_ 751-883 7.5e-24 a.39.1.5 Calcineurin B-l...
Pfam RPS-Blast
     PF00307 53-153 5e-06 Calponin homology (CH) domai...
     PF00307 166-268 2e-07 Calponin homology (CH) doma...
     PF08976 765-837 4e-04 EF-hand domain
     PF08726 841-907 2e-17 Ca2+ insensitive EF hand
Pfam Hmmer
    PF00307 51-154 5.2e-28 Calponin homology (CH) doma...
    PF00307 164-269 1.3e-29 Calponin homology (CH) dom...
    PF00435 293-402 8.7e-19 Spectrin repeat
    PF00435 413-517 1.2e-26 Spectrin repeat
    PF00435 529-639 1.2e-20 Spectrin repeat
    PF00435 649-751 1.2e-16 Spectrin repeat
    PF08726 841-907 4.6e-30 Ca2+ insensitive EF hand