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IID00132  Mothers against decapentaplegic homolog 4 (Homo sapiens) Q13485
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
552
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 10-140 Homo dimer :
 Evidence X-RAY 5mez A Reference
       Region 5mez A 10-14 disorder
       Region 5mez A 15-139 order
       Region 5mez A 140-140 disorder
 Evidence X-RAY 5mez B Reference
       Region 5mez B 10-14 disorder
       Region 5mez B 15-136 order
       Region 5mez B 137-140 disorder
 Evidence X-RAY 5mf0 A Reference
       Region 5mf0 A 10-15 disorder
       Region 5mf0 A 16-138 order
       Region 5mf0 A 139-140 disorder
 Evidence X-RAY 5mf0 B Reference
       Region 5mf0 B 10-13 disorder
       Region 5mf0 B 14-138 order
       Region 5mf0 B 139-140 disorder
Seq 10-140 Monomer :
 Evidence X-RAY 5mey A Reference
       Region 5mey A 10-14 disorder
       Region 5mey A 15-138 order
       Region 5mey A 139-140 disorder
Seq 133-149 Hetero tetramer : IID50169Complex
 Evidence X-RAY 5uwu D Reference
       Region 5uwu D 133-140 disorder
       Region 5uwu D 141-149 order
Seq 285-552 Homo trimer :
 Evidence X-RAY 1dd1 A Reference
       Region 1dd1 A 285-296 order
       Region 1dd1 A 297-310 disorder
       Region 1dd1 A 311-460 order
       Region 1dd1 A 461-486 disorder
       Region 1dd1 A 487-545 order
       Region 1dd1 A 546-552 disorder
 Evidence X-RAY 1dd1 B Reference
       Region 1dd1 B 285-296 order
       Region 1dd1 B 297-306 disorder
       Region 1dd1 B 307-469 order
       Region 1dd1 B 470-478 disorder
       Region 1dd1 B 479-552 order
 Evidence X-RAY 1dd1 C Reference
       Region 1dd1 C 285-294 order
       Region 1dd1 C 295-311 disorder
       Region 1dd1 C 312-468 order
       Region 1dd1 C 469-478 disorder
       Region 1dd1 C 479-552 order
 Evidence X-RAY 1g88 A Reference
       Region 1g88 A 285-296 order
       Region 1g88 A 297-310 disorder
       Region 1g88 A 311-460 order
       Region 1g88 A 461-486 disorder
       Region 1g88 A 487-545 order
       Region 1g88 A 546-552 disorder
 Evidence X-RAY 1g88 B Reference
       Region 1g88 B 285-296 order
       Region 1g88 B 297-308 disorder
       Region 1g88 B 309-466 order
       Region 1g88 B 467-478 disorder
       Region 1g88 B 479-550 order
       Region 1g88 B 551-552 disorder
 Evidence X-RAY 1g88 C Reference
       Region 1g88 C 285-294 order
       Region 1g88 C 295-311 disorder
       Region 1g88 C 312-465 order
       Region 1g88 C 466-478 disorder
       Region 1g88 C 479-550 order
       Region 1g88 C 551-552 disorder
 Evidence X-RAY 1ygs A Reference
       Region 1ygs A 319-456 order
       Region 1ygs A 457-491 disorder
       Region 1ygs A 492-543 order
       Region 1ygs A 544-552 disorder
Seq 314-549 Hetero dimer : P12757
 Evidence X-RAY 5c4v A Reference
       Region 5c4v A 314-318 disorder
       Region 5c4v A 319-459 order
       Region 5c4v A 460-490 disorder
       Region 5c4v A 491-541 order
       Region 5c4v A 542-549 disorder
 Evidence X-RAY 5c4v C Reference
       Region 5c4v C 314-318 disorder
       Region 5c4v C 319-455 order
       Region 5c4v C 456-491 disorder
       Region 5c4v C 492-542 order
       Region 5c4v C 543-549 disorder
 Evidence X-RAY 5c4v E Reference
       Region 5c4v E 314-318 disorder
       Region 5c4v E 319-463 order
       Region 5c4v E 464-491 disorder
       Region 5c4v E 492-542 order
       Region 5c4v E 543-549 disorder
Seq 314-549 Hetero trimer : IID00127Complex
 Evidence X-RAY 1u7v B Reference
       Region 1u7v B 314-461 order
       Region 1u7v B 462-489 disorder
       Region 1u7v B 490-549 order
Seq 314-552 Hetero trimer : IID00113Complex
 Evidence X-RAY 1u7f B Reference
       Region 1u7f B 314-417 order
       Region 1u7f B 418-423 disorder
       Region 1u7f B 424-455 order
       Region 1u7f B 456-489 disorder
       Region 1u7f B 490-546 order
       Region 1u7f B 547-552 disorder
Seq 319-552 Hetero dimer : IID00131Complex
 Evidence X-RAY 1mr1 A Reference
       Region 1mr1 A 319-461 order
       Region 1mr1 A 462-491 disorder
       Region 1mr1 A 492-543 order
       Region 1mr1 A 544-552 disorder
 Evidence X-RAY 1mr1 B Reference
       Region 1mr1 B 319-452 order
       Region 1mr1 B 453-491 disorder
       Region 1mr1 B 492-550 order
       Region 1mr1 B 551-552 disorder
Seqacetylation
    37-37 N6-acetyllysine
    428-428 N6-acetyllysine
    507-507 N6-acetyllysine
 
Prediction
DICHOT
Disorder 1-9,139-304,546-552
Known Domain 10-138,305-545
SCOPe RPS-Blast
     1ozjA 18-138 1e-35 d.164.1.1 SMAD MH1 domain
     1mjsA 320-544 3e-49 b.26.1.1 Smad1
SCOP Hmmer
     1mhdA_ 19-137 1.2e-43 d.164.1.1 SMAD MH1 domain
     1dd1A_ 287-544 6.4e-102 b.26.1.1 Smad1
Pfam RPS-Blast
     PF03165 78-137 6e-18 MH1 domain
     PF03166 344-530 2e-25 MH2 domain
Pfam Hmmer
    PF03165 37-137 1e-43 MH1 domain
    PF03166 321-530 5.8e-82 MH2 domain