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IID00134  Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (Homo sapiens) O14745
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
358
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 11-94 Hetero dimer : P09619
 Evidence X-RAY 1gq5 A Reference
       Region 1gq5 A 11-94 order
Seq 11-94 Hetero dimer : P07550
 Evidence X-RAY 1gq4 A Reference
       Region 1gq4 A 11-94 order
Seq 11-120 Monomer :
 Evidence X-RAY 1g9o A Reference
       Region 1g9o A 11-99 order
 Evidence X-RAY 1i92 A Reference
       Region 1i92 A 11-94 order
 Evidence X-RAY 4jl7 A Reference
       Region 4jl7 A 11-95 order
 Evidence X-RAY 4lmm A Reference
       Region 4lmm A 11-94 order
 Evidence NMR 2m0t A Reference
       Region 2m0t A 11-120 order
       Region 2m0t A 114-120 high_rmsd
 Evidence X-RAY 4mpa A Reference
       Region 4mpa A 11-94 order
 Evidence X-RAY 4n6x A Reference
       Region 4n6x A 11-94 order
 Evidence X-RAY 4pqw A Reference
       Region 4pqw A 11-94 order
Seq 11-120 Hetero dimer :
 Evidence NMR 2m0u A Reference
       Region 2m0u A 11-120 order
       Region 2m0u A 114-120 high_rmsd
Seq 150-234 Hetero dimer : IID00625Complex
 Evidence X-RAY 4q3h B Reference
       Region 4q3h B 150-234 order
Seq 150-234 Hetero dimer : IID00625Complex
 Evidence X-RAY 4q3h A Reference
       Region 4q3h A 150-234 order
Seq 150-270 Hetero dimer :
 Evidence NMR 2m0v A Reference
       Region 2m0v A 150-270 order
       Region 2m0v A 258-270 high_rmsd
Seq 150-270 Monomer :
 Evidence X-RAY 2ozf A Reference
       Region 2ozf A 150-235 order
 Evidence NMR 2jxo A Reference
       Region 2jxo A 150-240 order
       Region 2jxo A 238-240 high_rmsd
 Evidence NMR 2kjd A Reference
       Region 2kjd A 150-270 order
       Region 2kjd A 258-270 high_rmsd
Seq 150-358 Monomer :
 Evidence NMR 2krg A Reference
       Region 2krg A 150-252 order
       Region 2krg A 253-358 disorder
Seq 321-358 Hetero dimer : IID00344Complex
 Evidence X-RAY 1sgh B Reference
       Region 1sgh B 321-358 order
Seq 331-358 Hetero dimer : IID50114Complex
 Evidence X-RAY 2d10 E Reference
       Region 2d10 E 331-338 disorder
       Region 2d10 E 339-358 order
 Evidence X-RAY 2d10 F Reference
       Region 2d10 F 331-338 disorder
       Region 2d10 F 339-358 order
 Evidence X-RAY 2d10 G Reference
       Region 2d10 G 331-338 disorder
       Region 2d10 G 339-358 order
 Evidence X-RAY 2d10 H Reference
       Region 2d10 H 331-338 disorder
       Region 2d10 H 339-358 order
SeqProS verified 321-358 Hetero dimer : IID00344Complex
       Region 1sgh B 321-358 order
       Region 2krg A 253-358 disorder
SeqProS verified 339-358 Hetero dimer : IID50114Complex
       Region 2d10 E 339-358 order
       Region 2d10 F 339-358 order
       Region 2d10 G 339-358 order
       Region 2d10 H 339-358 order
       Region 2krg A 253-358 disorder
Seqphosphorylation
    2-2 Phosphoserine
    46-46 Phosphoserine
    162-162 Phosphoserine
    269-269 Phosphoserine
    280-280 Phosphoserine
    290-290 Phosphoserine
    291-291 Phosphoserine
    293-293 Phosphothreonine
    294-294 Phosphoserine
    299-299 Phosphoserine
    302-302 Phosphoserine
Seqacetylation
    2-2 N-acetylserine
 
Prediction
DICHOT
Disorder 1-10,113-149
Known Domain 11-112,150-358
SCOPe RPS-Blast
     4n6xA1 11-99 2e-41 b.36.1.1 Afadin
     4n6xA1 152-239 1e-37 b.36.1.1 Afadin
SCOP Hmmer
     1uitA_ 10-95 6.1e-29 PDZ domain-like
     1uitA_ 137-235 7.2e-29 PDZ domain-like
Pfam RPS-Blast
     PF17820 38-90 1e-10 PDZ domain
     PF17820 178-233 2e-11 PDZ domain
     PF09007 235-358 7e-25 EBP50, C-terminal
Pfam Hmmer
    PF17820 39-91 1.4e-18 PDZ domain
    PF17820 178-232 1.4e-18 PDZ domain
    PF09007 235-358 2.5e-46 EBP50, C-terminal