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IID00147  Splicing factor U2AF 65 kDa subunit (Homo sapiens) P26368
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
475
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 85-112 Hetero dimer : IID00205Complex
 Evidence X-RAY 1jmt B Reference
       Region 1jmt B 85-89 disorder
       Region 1jmt B 90-112 order
Seq 141-342 Monomer :
 Evidence X-RAY 5ev1 A Reference
       Region 5ev1 A 141-142 disorder
       Region 5ev1 A 143-340 order
       Region 5ev1 A 341-341 disorder
 Evidence X-RAY 5ev2 A Reference
       Region 5ev2 A 141-142 disorder
       Region 5ev2 A 143-340 order
       Region 5ev2 A 341-341 disorder
 Evidence X-RAY 5ev3 A Reference
       Region 5ev3 A 141-144 disorder
       Region 5ev3 A 145-340 order
       Region 5ev3 A 341-341 disorder
 Evidence X-RAY 5ev4 A Reference
       Region 5ev4 A 141-143 disorder
       Region 5ev4 A 144-340 order
       Region 5ev4 A 341-341 disorder
 Evidence NMR 2yh1 A Reference
       Region 2yh1 A 148-342 order
       Region 2yh1 A 233-256 high_rmsd
       Region 2yh1 A 339-342 high_rmsd
 Evidence NMR 2yh0 A Reference
       Region 2yh0 A 148-342 order
       Region 2yh0 A 231-256 high_rmsd
       Region 2yh0 A 338-342 high_rmsd
Seq 148-237 Monomer :
 Evidence X-RAY 2hzc A Reference
       Region 2hzc A 148-229 order
 Evidence NMR 1u2f A Reference
       Region 1u2f A 148-237 order
Seq 148-336 Homo dimer :
 Evidence X-RAY 2g4b A Reference
       Region 2g4b A 148-336 order
 Evidence X-RAY 4tu7 A Reference
       Region 4tu7 A 148-336 order
 Evidence X-RAY 4tu7 B Reference
       Region 4tu7 B 148-336 order
 Evidence X-RAY 4tu8 A Reference
       Region 4tu8 A 148-336 order
 Evidence X-RAY 4tu8 B Reference
       Region 4tu8 B 148-336 order
 Evidence X-RAY 4tu9 A Reference
       Region 4tu9 A 148-336 order
 Evidence X-RAY 4tu9 B Reference
       Region 4tu9 B 148-336 order
 Evidence X-RAY 3vaf A Reference
       Region 3vaf A 148-336 order
 Evidence X-RAY 3vaf B Reference
       Region 3vaf B 148-336 order
 Evidence X-RAY 3vag A Reference
       Region 3vag A 148-336 order
 Evidence X-RAY 3vag B Reference
       Region 3vag B 148-336 order
 Evidence X-RAY 3vah A Reference
       Region 3vah A 148-336 order
 Evidence X-RAY 3vah B Reference
       Region 3vah B 148-336 order
 Evidence X-RAY 3vai A Reference
       Region 3vai A 148-336 order
 Evidence X-RAY 3vai B Reference
       Region 3vai B 148-336 order
 Evidence X-RAY 3vaj A Reference
       Region 3vaj A 148-336 order
 Evidence X-RAY 3vaj B Reference
       Region 3vaj B 148-336 order
 Evidence X-RAY 3vak A Reference
       Region 3vak A 148-336 order
 Evidence X-RAY 3vak B Reference
       Region 3vak B 148-336 order
 Evidence X-RAY 3vam A Reference
       Region 3vam A 148-336 order
 Evidence X-RAY 3vam B Reference
       Region 3vam B 148-336 order
Seq 148-336 Homo tetramer :
 Evidence X-RAY 3val A Reference
       Region 3val A 148-336 order
 Evidence X-RAY 3val B Reference
       Region 3val B 148-336 order
 Evidence X-RAY 3val D Reference
       Region 3val D 148-336 order
 Evidence X-RAY 3val I Reference
       Region 3val I 148-336 order
Seq 258-342 Monomer :
 Evidence NMR 2u2f A Reference
       Region 2u2f A 258-342 order
Seq 372-475 Hetero dimer : IID00247Complex
 Evidence NMR 1o0p A Reference
       Region 1o0p A 372-475 order
 Evidence NMR 1opi A Reference
       Region 1opi A 372-475 order
       Region 1opi A 475-475 high_rmsd
Seq 372-475 Hetero dimer : IID00247Complex
 Evidence X-RAY 4fxw A Reference
       Region 4fxw A 375-475 order
 Evidence X-RAY 4fxw C Reference
       Region 4fxw C 375-420 order
       Region 4fxw C 421-421 disorder
       Region 4fxw C 422-475 order
 Evidence NMR 2m0g B Reference
       Region 2m0g B 372-475 order
Seqphosphorylation
    2-2 Phosphoserine
    79-79 Phosphoserine
    294-294 Phosphoserine
Seqacetylation
    2-2 N-acetylserine
    70-70 N6-acetyllysine; alternate
 
Prediction
DICHOT
Disorder 1-147,337-370
Known Domain 148-336,371-475
SCOPe RPS-Blast
     2fzrA1 148-229 1e-34 d.58.7.1 Alkylation repair AlkB homolog 8, ALK...
     2u2fA 258-342 2e-35 d.58.7.1 Alkylation repair AlkB homolog 8, ALKBH...
     3v4mA1 372-475 1e-44 d.58.7.1 Alkylation repair AlkB homolog 8, ALK...
SCOP Hmmer
     1u2fA_ 149-233 2.6e-20 d.58.7.1 Alkylation repa...
     1h2tZ_ 244-336 1.9e-23 d.58.7.1 Alkylation repa...
     2ditA1 373-469 6.6e-21 d.58.7.1 Alkylation repa...
Pfam RPS-Blast
     PF06495 5-136 7e-19 Fruit fly transformer protein
     PF16842 258-331 4e-04 Occluded RNA-recognition mo...
Pfam Hmmer
    PF00076 151-224 2.5e-10 RNA recognition motif. (a....
    PF00076 261-330 4.3e-21 RNA recognition motif. (a....
    PF00076 400-459 9e-10 RNA recognition motif. (a.k....