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IID00162  GTP-binding nuclear protein Ran (Homo sapiens) P62826
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
216
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-180 Hetero trimer : O94829
 Evidence X-RAY 3zjy A Reference
       Region 3zjy A 1-8 disorder
       Region 3zjy A 9-177 order
       Region 3zjy A 178-180 disorder
Seq 1-180 Hetero dimer : O94829
 Evidence X-RAY 3zjy D Reference
       Region 3zjy D 1-7 disorder
       Region 3zjy D 8-177 order
       Region 3zjy D 178-180 disorder
 Evidence X-RAY 3zjy F Reference
       Region 3zjy F 1-7 disorder
       Region 3zjy F 8-177 order
       Region 3zjy F 178-180 disorder
Seq 1-180 Hetero dimer : IID50151Complex
 Evidence X-RAY 3nc1 C Reference
       Region 3nc1 C 1-7 disorder
       Region 3nc1 C 8-180 order
Seq 1-216 Hetero dimer : P18754
 Evidence X-RAY 1i2m A Reference
       Region 1i2m A 1-7 disorder
       Region 1i2m A 8-31 order
       Region 1i2m A 32-36 disorder
       Region 1i2m A 37-177 order
       Region 1i2m A 178-216 disorder
 Evidence X-RAY 1i2m C Reference
       Region 1i2m C 1-7 disorder
       Region 1i2m C 8-31 order
       Region 1i2m C 32-37 disorder
       Region 1i2m C 38-177 order
       Region 1i2m C 178-216 disorder
Seq 1-216 Hetero tetramer : IID50169Complex,IID50175Complex
 Evidence X-RAY 5uwt A Reference
       Region 5uwt A 1-8 disorder
       Region 5uwt A 9-216 order
Seq 1-216 Hetero tetramer : IID50169Complex,IID50175Complex
 Evidence X-RAY 5dif A Reference
       Region 5dif A 1-7 disorder
       Region 5dif A 8-216 order
Seq 1-216 Hetero tetramer : IID50169Complex,IID50175Complex
 Evidence X-RAY 5uwq A Reference
       Region 5uwq A 1-8 disorder
       Region 5uwq A 9-187 order
       Region 5uwq A 188-189 disorder
       Region 5uwq A 190-216 order
 Evidence X-RAY 5uwr A Reference
       Region 5uwr A 1-8 disorder
       Region 5uwr A 9-187 order
       Region 5uwr A 188-191 disorder
       Region 5uwr A 192-216 order
Seq 1-216 Hetero dimer : IID00386Complex
 Evidence X-RAY 1ibr A Reference
       Region 1ibr A 1-8 disorder
       Region 1ibr A 9-176 order
       Region 1ibr A 177-216 disorder
 Evidence X-RAY 1ibr C Reference
       Region 1ibr C 1-8 disorder
       Region 1ibr C 9-176 order
       Region 1ibr C 177-216 disorder
Seq 1-216 Hetero dimer : Q06142
 Evidence X-RAY 3ea5 A Reference
       Region 3ea5 A 1-5 disorder
       Region 3ea5 A 6-179 order
       Region 3ea5 A 180-216 disorder
 Evidence X-RAY 3ea5 C Reference
       Region 3ea5 C 1-8 disorder
       Region 3ea5 C 9-177 order
       Region 3ea5 C 178-216 disorder
Seq 1-216 Hetero dimer : IID00632Complex
 Evidence X-RAY 4c0q C Reference
       Region 4c0q C 2-8 disorder
       Region 4c0q C 9-177 order
       Region 4c0q C 178-216 disorder
 Evidence X-RAY 4c0q D Reference
       Region 4c0q D 2-8 disorder
       Region 4c0q D 9-177 order
       Region 4c0q D 178-186 disorder
       Region 4c0q D 187-192 order
       Region 4c0q D 193-216 disorder
 Evidence X-RAY 4ol0 A Reference
       Region 4ol0 A 1-7 disorder
       Region 4ol0 A 8-179 order
       Region 4ol0 A 180-216 disorder
Seq 1-216 Hetero dimer : IID00094Complex
 Evidence X-RAY 1qbk C Reference
       Region 1qbk C 1-7 disorder
       Region 1qbk C 8-197 order
       Region 1qbk C 198-216 disorder
Seq 1-216 Hetero tetramer : IID50169Complex,IID50175Complex
 Evidence X-RAY 5dhf A Reference
       Region 5dhf A 1-8 disorder
       Region 5dhf A 9-187 order
       Region 5dhf A 188-190 disorder
       Region 5dhf A 191-216 order
Seq 1-216 Hetero octamer : P49791
 Evidence X-RAY 3ch5 A Reference
       Region 3ch5 A 1-6 disorder
       Region 3ch5 A 7-136 order
       Region 3ch5 A 137-142 disorder
       Region 3ch5 A 143-205 order
       Region 3ch5 A 206-216 disorder
Seq 1-216 Hetero trimer : IID50169Complex,IID50175Complex
 Evidence X-RAY 4gmx A Reference
       Region 4gmx A 1-7 disorder
       Region 4gmx A 8-188 order
       Region 4gmx A 189-192 disorder
       Region 4gmx A 193-216 order
 Evidence X-RAY 4gpt A Reference
       Region 4gpt A 1-8 disorder
       Region 4gpt A 9-216 order
 Evidence X-RAY 4hat A Reference
       Region 4hat A 1-7 disorder
       Region 4hat A 8-216 order
 Evidence X-RAY 4hau A Reference
       Region 4hau A 1-8 disorder
       Region 4hau A 9-186 order
       Region 4hau A 187-195 disorder
       Region 4hau A 196-216 order
 Evidence X-RAY 4hav A Reference
       Region 4hav A 1-8 disorder
       Region 4hav A 9-185 order
       Region 4hav A 186-197 disorder
       Region 4hav A 198-216 order
 Evidence X-RAY 4haw A Reference
       Region 4haw A 1-8 disorder
       Region 4haw A 9-185 order
       Region 4haw A 186-197 disorder
       Region 4haw A 198-216 order
 Evidence X-RAY 4hax A Reference
       Region 4hax A 1-7 disorder
       Region 4hax A 8-186 order
       Region 4hax A 187-195 disorder
       Region 4hax A 196-216 order
 Evidence X-RAY 4hay A Reference
       Region 4hay A 1-8 disorder
       Region 4hay A 9-186 order
       Region 4hay A 187-194 disorder
       Region 4hay A 195-216 order
 Evidence X-RAY 4haz A Reference
       Region 4haz A 1-8 disorder
       Region 4haz A 9-187 order
       Region 4haz A 188-193 disorder
       Region 4haz A 194-216 order
 Evidence X-RAY 4hb0 A Reference
       Region 4hb0 A 1-8 disorder
       Region 4hb0 A 9-188 order
       Region 4hb0 A 189-191 disorder
       Region 4hb0 A 192-216 order
 Evidence X-RAY 4hb2 A Reference
       Region 4hb2 A 1-8 disorder
       Region 4hb2 A 9-188 order
       Region 4hb2 A 189-192 disorder
       Region 4hb2 A 193-216 order
 Evidence X-RAY 4hb3 A Reference
       Region 4hb3 A 1-8 disorder
       Region 4hb3 A 9-187 order
       Region 4hb3 A 188-193 disorder
       Region 4hb3 A 194-216 order
 Evidence X-RAY 4hb4 A Reference
       Region 4hb4 A 1-7 disorder
       Region 4hb4 A 8-216 order
 Evidence X-RAY 5jlj A Reference
       Region 5jlj A 1-8 disorder
       Region 5jlj A 9-187 order
       Region 5jlj A 188-193 disorder
       Region 5jlj A 194-216 order
Seq 1-216 Hetero tetramer : IID50169Complex,IID50175Complex
 Evidence X-RAY 5uwu A Reference
       Region 5uwu A 1-8 disorder
       Region 5uwu A 9-216 order
Seq 1-216 Hetero tetramer : IID50169Complex,IID50175Complex
 Evidence X-RAY 5dh9 A Reference
       Region 5dh9 A 1-8 disorder
       Region 5dh9 A 9-186 order
       Region 5dh9 A 187-189 disorder
       Region 5dh9 A 190-216 order
Seq 1-216 Monomer :
 Evidence X-RAY 5ciq A Reference
       Region 5ciq A 1-8 disorder
       Region 5ciq A 9-207 order
       Region 5ciq A 208-216 disorder
 Evidence X-RAY 5ciq B Reference
       Region 5ciq B 1-7 disorder
       Region 5ciq B 8-207 order
       Region 5ciq B 208-216 disorder
 Evidence X-RAY 5cit A Reference
       Region 5cit A 1-7 disorder
       Region 5cit A 8-206 order
       Region 5cit A 207-216 disorder
 Evidence X-RAY 5cit B Reference
       Region 5cit B 1-7 disorder
       Region 5cit B 8-204 order
       Region 5cit B 205-216 disorder
 Evidence X-RAY 5ciw A Reference
       Region 5ciw A 1-8 disorder
       Region 5ciw A 9-207 order
       Region 5ciw A 208-216 disorder
 Evidence X-RAY 5ciw B Reference
       Region 5ciw B 1-8 disorder
       Region 5ciw B 9-207 order
       Region 5ciw B 208-216 disorder
 Evidence X-RAY 5cj2 A Reference
       Region 5cj2 A 1-7 disorder
       Region 5cj2 A 8-204 order
       Region 5cj2 A 205-216 disorder
 Evidence X-RAY 5cj2 B Reference
       Region 5cj2 B 1-6 disorder
       Region 5cj2 B 7-205 order
       Region 5cj2 B 206-216 disorder
 Evidence X-RAY 5cj2 C Reference
       Region 5cj2 C 1-8 disorder
       Region 5cj2 C 9-206 order
       Region 5cj2 C 207-216 disorder
 Evidence X-RAY 5cj2 D Reference
       Region 5cj2 D 1-6 disorder
       Region 5cj2 D 7-204 order
       Region 5cj2 D 205-216 disorder
 Evidence X-RAY 5cj2 E Reference
       Region 5cj2 E 1-7 disorder
       Region 5cj2 E 8-207 order
       Region 5cj2 E 208-216 disorder
 Evidence X-RAY 5cj2 F Reference
       Region 5cj2 F 1-7 disorder
       Region 5cj2 F 8-204 order
       Region 5cj2 F 205-216 disorder
 Evidence X-RAY 5cj2 G Reference
       Region 5cj2 G 1-7 disorder
       Region 5cj2 G 8-204 order
       Region 5cj2 G 205-216 disorder
 Evidence X-RAY 5cj2 H Reference
       Region 5cj2 H 1-7 disorder
       Region 5cj2 H 8-204 order
       Region 5cj2 H 205-216 disorder
 Evidence X-RAY 3gj0 A Reference
       Region 3gj0 A 2-207 order
       Region 3gj0 A 208-216 disorder
 Evidence X-RAY 3gj0 B Reference
       Region 3gj0 B 2-7 disorder
       Region 3gj0 B 8-68 order
       Region 3gj0 B 69-74 disorder
       Region 3gj0 B 75-206 order
       Region 3gj0 B 207-216 disorder
 Evidence NMR 2mmc A Reference
       Region 2mmc A 1-216 order
       Region 2mmc A 1-5 high_rmsd
 Evidence NMR 2mmg A Reference
       Region 2mmg A 1-216 order
       Region 2mmg A 181-216 high_rmsd
 Evidence NMR 2n1b A Reference
       Region 2n1b A 1-216 order
       Region 2n1b A 1-3 high_rmsd
Seq 1-216 Hetero trimer : IID50151Complex
 Evidence X-RAY 3gjx C Reference
       Region 3gjx C 1-8 disorder
       Region 3gjx C 9-179 order
       Region 3gjx C 180-216 disorder
 Evidence X-RAY 3gjx F Reference
       Region 3gjx F 1-8 disorder
       Region 3gjx F 9-179 order
       Region 3gjx F 180-216 disorder
 Evidence X-RAY 3nby C Reference
       Region 3nby C 5-8 disorder
       Region 3nby C 9-179 order
       Region 3nby C 180-180 disorder
 Evidence X-RAY 3nby F Reference
       Region 3nby F 5-8 disorder
       Region 3nby F 9-179 order
       Region 3nby F 180-180 disorder
Seq 1-216 Hetero tetramer : IID50169Complex,IID50175Complex
 Evidence X-RAY 5uwp A Reference
       Region 5uwp A 1-7 disorder
       Region 5uwp A 8-216 order
Seq 1-216 Hetero tetramer : IID50169Complex,IID50175Complex
 Evidence X-RAY 5uwi A Reference
       Region 5uwi A 1-8 disorder
       Region 5uwi A 9-216 order
Seq 1-216 Hetero tetramer : IID50169Complex,IID50175Complex
 Evidence X-RAY 5uww A Reference
       Region 5uww A 1-8 disorder
       Region 5uww A 9-187 order
       Region 5uww A 188-189 disorder
       Region 5uww A 190-216 order
Seq 1-216 Hetero tetramer : IID50169Complex,IID50175Complex
 Evidence X-RAY 5uwj A Reference
       Region 5uwj A 1-8 disorder
       Region 5uwj A 9-187 order
       Region 5uwj A 188-189 disorder
       Region 5uwj A 190-216 order
 Evidence X-RAY 5uwo A Reference
       Region 5uwo A 1-8 disorder
       Region 5uwo A 9-186 order
       Region 5uwo A 187-189 disorder
       Region 5uwo A 190-216 order
Seq 1-216 Hetero dimer : IID00151Complex
 Evidence X-RAY 5cll A Reference
       Region 5cll A 1-7 disorder
       Region 5cll A 8-186 order
       Region 5cll A 187-191 disorder
 Evidence X-RAY 5cll C Reference
       Region 5cll C 1-7 disorder
       Region 5cll C 8-186 order
       Region 5cll C 187-191 disorder
 Evidence X-RAY 5clq A Reference
       Region 5clq A 1-4 disorder
       Region 5clq A 5-211 order
       Region 5clq A 212-216 disorder
 Evidence X-RAY 5clq C Reference
       Region 5clq C 1-7 disorder
       Region 5clq C 8-139 order
       Region 5clq C 140-143 disorder
       Region 5clq C 144-211 order
       Region 5clq C 212-216 disorder
 Evidence X-RAY 1rrp A Reference
       Region 1rrp A 8-211 order
 Evidence X-RAY 1rrp C Reference
       Region 1rrp C 8-187 order
       Region 1rrp C 188-211 disorder
Seq 1-216 Hetero tetramer : IID50169Complex,IID50175Complex
 Evidence X-RAY 5dha A Reference
       Region 5dha A 1-8 disorder
       Region 5dha A 9-187 order
       Region 5dha A 188-189 disorder
       Region 5dha A 190-216 order
Seq 1-216 Hetero tetramer : IID50169Complex,IID50175Complex
 Evidence X-RAY 5uws A Reference
       Region 5uws A 1-8 disorder
       Region 5uws A 9-187 order
       Region 5uws A 188-189 disorder
       Region 5uws A 190-216 order
Seq 1-216 Hetero trimer : IID00337Complex,IID50116Complex
 Evidence X-RAY 1k5d A Reference
       Region 1k5d A 1-7 disorder
       Region 1k5d A 8-213 order
       Region 1k5d A 214-216 disorder
 Evidence X-RAY 1k5d D Reference
       Region 1k5d D 1-7 disorder
       Region 1k5d D 8-213 order
       Region 1k5d D 214-216 disorder
 Evidence X-RAY 1k5d G Reference
       Region 1k5d G 1-7 disorder
       Region 1k5d G 8-213 order
       Region 1k5d G 214-216 disorder
 Evidence X-RAY 1k5d J Reference
       Region 1k5d J 1-7 disorder
       Region 1k5d J 8-213 order
       Region 1k5d J 214-216 disorder
 Evidence X-RAY 1k5g A Reference
       Region 1k5g A 1-7 disorder
       Region 1k5g A 8-213 order
       Region 1k5g A 214-216 disorder
 Evidence X-RAY 1k5g D Reference
       Region 1k5g D 1-7 disorder
       Region 1k5g D 8-213 order
       Region 1k5g D 214-216 disorder
 Evidence X-RAY 1k5g G Reference
       Region 1k5g G 1-7 disorder
       Region 1k5g G 8-213 order
       Region 1k5g G 214-216 disorder
 Evidence X-RAY 1k5g J Reference
       Region 1k5g J 1-7 disorder
       Region 1k5g J 8-213 order
       Region 1k5g J 214-216 disorder
Seq 1-216 Hetero tetramer : IID50169Complex,IID50175Complex
 Evidence X-RAY 5uwh A Reference
       Region 5uwh A 1-8 disorder
       Region 5uwh A 9-187 order
       Region 5uwh A 188-192 disorder
       Region 5uwh A 193-216 order
Seq 1-216 Hetero tetramer : IID50169Complex,IID50175Complex
 Evidence X-RAY 5di9 A Reference
       Region 5di9 A 1-8 disorder
       Region 5di9 A 9-216 order
Seq 1-216 Hetero tetramer : P49791
 Evidence X-RAY 3ch5 A Reference
       Region 3ch5 A 1-6 disorder
       Region 3ch5 A 7-136 order
       Region 3ch5 A 137-142 disorder
       Region 3ch5 A 143-205 order
       Region 3ch5 A 206-216 disorder
Seq 1-216 Hetero trimer : IID50175Complex
 Evidence X-RAY 4wvf A Reference
       Region 4wvf A 1-7 disorder
       Region 4wvf A 8-216 order
Seq 2-216 Hetero dimer : P49791
 Evidence X-RAY 3gj4 A Reference
       Region 3gj4 A 2-7 disorder
       Region 3gj4 A 8-208 order
       Region 3gj4 A 209-216 disorder
 Evidence X-RAY 3gj4 C Reference
       Region 3gj4 C 2-7 disorder
       Region 3gj4 C 8-207 order
       Region 3gj4 C 208-216 disorder
Seq 2-216 Hetero dimer : P49791
 Evidence X-RAY 3gj6 A Reference
       Region 3gj6 A 2-5 disorder
       Region 3gj6 A 6-208 order
       Region 3gj6 A 209-216 disorder
Seq 2-216 Hetero dimer : P49791
 Evidence X-RAY 3gj3 A Reference
       Region 3gj3 A 2-5 disorder
       Region 3gj3 A 6-207 order
       Region 3gj3 A 208-216 disorder
 Evidence X-RAY 3gj7 A Reference
       Region 3gj7 A 2-6 disorder
       Region 3gj7 A 7-207 order
       Region 3gj7 A 208-216 disorder
 Evidence X-RAY 3gj7 C Reference
       Region 3gj7 C 2-6 disorder
       Region 3gj7 C 7-208 order
       Region 3gj7 C 209-216 disorder
Seq 2-216 Hetero dimer : P49791
 Evidence X-RAY 3gj5 A Reference
       Region 3gj5 A 2-7 disorder
       Region 3gj5 A 8-208 order
       Region 3gj5 A 209-216 disorder
 Evidence X-RAY 3gj5 C Reference
       Region 3gj5 C 2-7 disorder
       Region 3gj5 C 8-208 order
       Region 3gj5 C 209-216 disorder
 Evidence X-RAY 3gj8 A Reference
       Region 3gj8 A 2-5 disorder
       Region 3gj8 A 6-209 order
       Region 3gj8 A 210-216 disorder
 Evidence X-RAY 3gj8 C Reference
       Region 3gj8 C 2-5 disorder
       Region 3gj8 C 6-209 order
       Region 3gj8 C 210-216 disorder
Seq 5-180 Hetero trimer : P63241,Q9ESJ0
 Evidence X-RAY 5dlq C Reference
       Region 5dlq C 5-6 disorder
       Region 5dlq C 7-179 order
       Region 5dlq C 180-180 disorder
 Evidence X-RAY 5dlq D Reference
       Region 5dlq D 5-6 disorder
       Region 5dlq D 7-178 order
       Region 5dlq D 179-180 disorder
Seq 5-180 Hetero hexamer : IID50151Complex
 Evidence X-RAY 3nc0 C Reference
       Region 3nc0 C 5-7 disorder
       Region 3nc0 C 8-180 order
 Evidence X-RAY 3nc0 F Reference
       Region 3nc0 F 5-7 disorder
       Region 3nc0 F 8-180 order
Seq 5-180 Hetero tetramer : IID50151Complex
 Evidence X-RAY 3nbz C Reference
       Region 3nbz C 5-7 disorder
       Region 3nbz C 8-180 order
 Evidence X-RAY 3nbz F Reference
       Region 3nbz F 5-7 disorder
       Region 3nbz F 8-180 order
 Evidence X-RAY 3nbz C Reference
       Region 3nbz C 5-7 disorder
       Region 3nbz C 8-180 order
 Evidence X-RAY 3nbz F Reference
       Region 3nbz F 5-7 disorder
       Region 3nbz F 8-180 order
Seq 5-180 Hetero pentamer : IID50151Complex
 Evidence X-RAY 3nc0 C Reference
       Region 3nc0 C 5-7 disorder
       Region 3nc0 C 8-180 order
 Evidence X-RAY 3nc0 F Reference
       Region 3nc0 F 5-7 disorder
       Region 3nc0 F 8-180 order
Seq 8-179 Hetero pentamer : IID00357Complex
 Evidence X-RAY 5dis B Reference
       Region 5dis B 8-179 order
Seq 31-43 Hetero dimer : Q8IXJ6
 Evidence X-RAY 5fyq D Reference
       Region 5fyq D 31-32 disorder
       Region 5fyq D 33-40 order
       Region 5fyq D 41-43 disorder
 Evidence X-RAY 5fyq C Reference
       Region 5fyq C 31-33 disorder
       Region 5fyq C 34-40 order
       Region 5fyq C 41-43 disorder
SeqProS verified 177-216 Hetero trimer : IID50169Complex,IID50175Complex
       Region 4gpt A 9-216 order
       Region 4hb4 A 8-216 order
       Region 4hat A 8-216 order
       Region 4hav A 198-216 order
       Region 4hb0 A 192-216 order
       Region 4haz A 194-216 order
       Region 4gmx A 193-216 order
       Region 4hb2 A 193-216 order
       Region 4haw A 198-216 order
       Region 4hb3 A 194-216 order
       Region 4hax A 196-216 order
       Region 4hau A 196-216 order
       Region 4hay A 195-216 order
       Region 1ibr A 177-216 disorder
SeqProS verified 180-211 This region (180-211) is ordered in the complex with RanBP2, but is disordered in the complex with importin. The structure of Ran-GTP is not determined in the free state. Hetero dimer : IID00151Complex
       Region 1rrp A 8-211 order
       Region 1ibr A 177-216 disorder
SeqProS verified 180-213 This region (180-213) is ordered in the complex with Ran-BP1, but is disordered in the complex with importin.The structure of Ran-GTP is not determined in the free state. Hetero trimer : IID00337Complex,IID50116Complex
       Region 1k5g A 8-213 order
       Region 1k5g D 8-213 order
       Region 1k5g G 8-213 order
       Region 1k5g J 8-213 order
       Region 1k5d A 8-213 order
       Region 1k5d D 8-213 order
       Region 1k5d G 8-213 order
       Region 1k5d J 8-213 order
       Region 1ibr A 177-216 disorder
Seqphosphorylation
    24-24 Phosphothreonine
Seqacetylation
    2-2 N-acetylalanine
    60-60 N6-acetyllysine
    71-71 N6-acetyllysine; alternate
    99-99 N6-acetyllysine
    134-134 N6-acetyllysine
    159-159 N6-acetyllysine; alternate
 
Prediction
DICHOT
Disorder 1-7,178-216
Known Domain 8-177
SCOPe RPS-Blast
     3gj0A1 2-207 1e-95 c.37.1.8 ADP-ribosylation factor
SCOP Hmmer
     1byuA_ 7-196 2.8e-53 c.37.1.8 ADP-ribosylation ...
Pfam RPS-Blast
     PF08477 12-125 2e-20 Ras of Complex, Roc, domain ...
Pfam Hmmer
    PF00071 12-168 1.5e-53 Ras family