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IID00167  Nuclear cap-binding protein subunit 1 (Homo sapiens) Q09161
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
790
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-790 Hetero trimer : IID00153Complex,IID00238Complex
 Evidence X-RAY 3fey A Reference
       Region 3fey A 1-1 disorder
       Region 3fey A 2-525 order
       Region 3fey A 526-538 disorder
       Region 3fey A 539-667 order
       Region 3fey A 668-682 disorder
       Region 3fey A 683-790 order
Seq 1-790 Hetero trimer : IID00153Complex,IID00238Complex
 Evidence X-RAY 3fex A Reference
       Region 3fex A 1-1 disorder
       Region 3fex A 2-40 order
       Region 3fex A 41-43 disorder
       Region 3fex A 44-158 order
       Region 3fex A 159-160 disorder
       Region 3fex A 161-525 order
       Region 3fex A 526-538 disorder
       Region 3fex A 539-667 order
       Region 3fex A 668-682 disorder
       Region 3fex A 683-790 order
Seq 1-790 Hetero dimer : IID00238Complex
 Evidence X-RAY 1h2v C Reference
       Region 1h2v C 20-28 disorder
       Region 1h2v C 29-526 order
       Region 1h2v C 527-538 disorder
       Region 1h2v C 539-663 order
       Region 1h2v C 664-691 disorder
       Region 1h2v C 692-790 order
 Evidence X-RAY 1h6k A Reference
       Region 1h6k A 20-26 disorder
       Region 1h6k A 27-526 order
       Region 1h6k A 527-538 disorder
       Region 1h6k A 539-665 order
       Region 1h6k A 666-670 disorder
       Region 1h6k A 671-684 order
       Region 1h6k A 685-689 disorder
       Region 1h6k A 690-790 order
 Evidence X-RAY 1h6k B Reference
       Region 1h6k B 20-25 disorder
       Region 1h6k B 26-526 order
       Region 1h6k B 527-538 disorder
       Region 1h6k B 539-664 order
       Region 1h6k B 665-670 disorder
       Region 1h6k B 671-684 order
       Region 1h6k B 685-688 disorder
       Region 1h6k B 689-790 order
 Evidence X-RAY 1h6k C Reference
       Region 1h6k C 20-25 disorder
       Region 1h6k C 26-527 order
       Region 1h6k C 528-537 disorder
       Region 1h6k C 538-665 order
       Region 1h6k C 666-670 disorder
       Region 1h6k C 671-684 order
       Region 1h6k C 685-687 disorder
       Region 1h6k C 688-790 order
 Evidence X-RAY 1n52 A Reference
       Region 1n52 A 1-25 disorder
       Region 1n52 A 26-526 order
       Region 1n52 A 527-538 disorder
       Region 1n52 A 539-665 order
       Region 1n52 A 666-686 disorder
       Region 1n52 A 687-790 order
 Evidence X-RAY 1n54 A Reference
       Region 1n54 A 1-23 disorder
       Region 1n54 A 24-526 order
       Region 1n54 A 527-538 disorder
       Region 1n54 A 539-665 order
       Region 1n54 A 666-687 disorder
       Region 1n54 A 688-790 order
 Evidence X-RAY 5oob F Reference
       Region 5oob F 20-23 disorder
       Region 5oob F 24-484 order
       Region 5oob F 485-497 disorder
       Region 5oob F 498-525 order
       Region 5oob F 526-539 disorder
       Region 5oob F 540-665 order
       Region 5oob F 666-687 disorder
       Region 5oob F 688-790 order
Seq 20-652,702-790 Hetero trimer : IID00238Complex
 Evidence X-RAY 1h2t C Reference
       Region 1h2t C 20-28 disorder
       Region 1h2t C 29-527 order
       Region 1h2t C 528-537 disorder
       Region 1h2t C 538-652 order
       Region 1h2t C 702-790 order
Seq 20-790 Hetero trimer : IID00238Complex,Q9BXP5
 Evidence X-RAY 5oo6 A Reference
       Region 5oo6 A 20-26 disorder
       Region 5oo6 A 27-486 order
       Region 5oo6 A 487-496 disorder
       Region 5oo6 A 497-527 order
       Region 5oo6 A 528-539 disorder
       Region 5oo6 A 540-670 order
       Region 5oo6 A 671-686 disorder
       Region 5oo6 A 687-790 order
 Evidence X-RAY 5oo6 D Reference
       Region 5oo6 D 20-26 disorder
       Region 5oo6 D 27-527 order
       Region 5oo6 D 528-539 disorder
       Region 5oo6 D 540-670 order
       Region 5oo6 D 671-682 disorder
       Region 5oo6 D 683-790 order
 Evidence X-RAY 5oo6 G Reference
       Region 5oo6 G 20-26 disorder
       Region 5oo6 G 27-486 order
       Region 5oo6 G 487-496 disorder
       Region 5oo6 G 497-527 order
       Region 5oo6 G 528-539 disorder
       Region 5oo6 G 540-670 order
       Region 5oo6 G 671-682 disorder
       Region 5oo6 G 683-790 order
 Evidence X-RAY 5oo6 J Reference
       Region 5oo6 J 20-26 disorder
       Region 5oo6 J 27-486 order
       Region 5oo6 J 487-496 disorder
       Region 5oo6 J 497-527 order
       Region 5oo6 J 528-539 disorder
       Region 5oo6 J 540-670 order
       Region 5oo6 J 671-682 disorder
       Region 5oo6 J 683-790 order
 Evidence X-RAY 5oo6 M Reference
       Region 5oo6 M 20-26 disorder
       Region 5oo6 M 27-527 order
       Region 5oo6 M 528-539 disorder
       Region 5oo6 M 540-670 order
       Region 5oo6 M 671-682 disorder
       Region 5oo6 M 683-790 order
 Evidence X-RAY 5oo6 P Reference
       Region 5oo6 P 20-26 disorder
       Region 5oo6 P 27-486 order
       Region 5oo6 P 487-496 disorder
       Region 5oo6 P 497-527 order
       Region 5oo6 P 528-539 disorder
       Region 5oo6 P 540-670 order
       Region 5oo6 P 671-682 disorder
       Region 5oo6 P 683-790 order
 Evidence X-RAY 5oo6 S Reference
       Region 5oo6 S 20-26 disorder
       Region 5oo6 S 27-486 order
       Region 5oo6 S 487-496 disorder
       Region 5oo6 S 497-527 order
       Region 5oo6 S 528-539 disorder
       Region 5oo6 S 540-670 order
       Region 5oo6 S 671-686 disorder
       Region 5oo6 S 687-790 order
 Evidence X-RAY 5oo6 V Reference
       Region 5oo6 V 20-26 disorder
       Region 5oo6 V 27-486 order
       Region 5oo6 V 487-496 disorder
       Region 5oo6 V 497-527 order
       Region 5oo6 V 528-539 disorder
       Region 5oo6 V 540-670 order
       Region 5oo6 V 671-686 disorder
       Region 5oo6 V 687-790 order
Seq 20-790 Hetero trimer : IID00030Complex,IID00238Complex
 Evidence X-RAY 5oob A Reference
       Region 5oob A 20-25 disorder
       Region 5oob A 26-526 order
       Region 5oob A 527-534 disorder
       Region 5oob A 535-668 order
       Region 5oob A 669-686 disorder
       Region 5oob A 687-790 order
 Evidence X-RAY 5oob C Reference
       Region 5oob C 20-22 disorder
       Region 5oob C 23-525 order
       Region 5oob C 526-538 disorder
       Region 5oob C 539-664 order
       Region 5oob C 665-688 disorder
       Region 5oob C 689-790 order
 Evidence X-RAY 5oob I Reference
       Region 5oob I 20-27 disorder
       Region 5oob I 28-526 order
       Region 5oob I 527-539 disorder
       Region 5oob I 540-665 order
       Region 5oob I 666-686 disorder
       Region 5oob I 687-790 order
Seq 20-652,702-790 Hetero trimer : IID00238Complex
 Evidence X-RAY 1h2u A Reference
       Region 1h2u A 20-25 disorder
       Region 1h2u A 26-527 order
       Region 1h2u A 528-538 disorder
       Region 1h2u A 539-652 order
       Region 1h2u A 702-790 order
Seq 20-652,702-790 Hetero trimer : IID00238Complex
 Evidence X-RAY 1h2u B Reference
       Region 1h2u B 20-26 disorder
       Region 1h2u B 27-527 order
       Region 1h2u B 528-537 disorder
       Region 1h2u B 538-652 order
       Region 1h2u B 702-790 order
SeqProS verified 2-25 Nuclear Localization Signal (NLS) Hetero trimer : IID00153Complex,IID00238Complex
       Region 3fey A 2-525 order
       Region 1n52 A 1-25 disorder
SeqProS verified 2-25 Nuclear Localization Signal (NLS) Hetero trimer : IID00153Complex,IID00238Complex
       Region 3fex A 2-40 order
       Region 1n52 A 1-25 disorder
Seqphosphorylation
    7-7 Phosphoserine; by RPS6KB1
    21-21 Phosphothreonine; by RPS6KB1
    22-22 Phosphoserine; by RPS6KB1
    201-201 Phosphoserine
Seqacetylation
    204-204 N6-acetyllysine
    698-698 N6-acetyllysine
 
Prediction
DICHOT
Disorder 1-28
Known Domain 29-790
SCOPe RPS-Blast
     1h2vC1 29-290 2e-81 a.118.1.14 CBP80, 80KDa nuclear cap-binding prot...
     1h2vC2 291-480 8e-67 a.118.1.14 CBP80, 80KDa nuclear cap-binding pro...
     1h2vC3 481-790 2e-94 a.118.1.14 CBP80, 80KDa nuclear cap-binding pro...
SCOP Hmmer
     1h6kA1 28-290 6.2e-91 a.118.1.14 CBP80, 80KDa n...
     1h6kA2 291-479 5.1e-80 a.118.1.14 CBP80, 80KDa ...
     1h6kA3 481-790 5.7e-108 a.118.1.14 CBP80, 80KDa...
Pfam RPS-Blast
     PF09088 306-470 4e-43 MIF4G like
     PF09090 485-757 2e-44 MIF4G like
Pfam Hmmer
    PF02854 31-240 1.3e-34 MIF4G domain
    PF09088 326-470 7.4e-40 MIF4G like
    PF09090 485-758 3.8e-89 MIF4G like