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IID00168  Serine/threonine-protein kinase 4 (Homo sapiens) Q13043
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
487
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 2-311 Monomer :
 Evidence X-RAY 3com A Reference
       Region 3com A 2-28 disorder
       Region 3com A 29-37 order
       Region 3com A 38-41 disorder
       Region 3com A 42-298 order
       Region 3com A 299-311 disorder
 Evidence X-RAY 3com B Reference
       Region 3com B 2-15 disorder
       Region 3com B 16-37 order
       Region 3com B 38-41 disorder
       Region 3com B 42-300 order
       Region 3com B 301-311 disorder
Seqdisorder 326-401
 Evidence CD¸ NMR Reference
       Region 326-401 disorder
Seq 343-356 Hetero dimer : Q9H8S9
 Evidence X-RAY 5twg E Reference
       Region 5twg E 343-353 disorder
       Region 5twg E 354-356 order
Seq 358-374 Hetero tetramer : Q9H8S9
 Evidence X-RAY 5twh E Reference
       Region 5twh E 358-367 disorder
       Region 5twh E 368-371 order
       Region 5twh E 372-374 disorder
Seq 432-480 Hetero dimer : IID00631Complex
 Evidence X-RAY 4oh8 A Reference
       Region 4oh8 A 432-437 disorder
       Region 4oh8 A 438-480 order
Seq 432-480 Homo dimer :
 Evidence X-RAY 4nr2 A Reference
       Region 4nr2 A 432-480 order
 Evidence X-RAY 4nr2 B Reference
       Region 4nr2 B 432-433 disorder
       Region 4nr2 B 434-480 order
 Evidence X-RAY 4nr2 C Reference
       Region 4nr2 C 432-480 order
 Evidence X-RAY 4nr2 D Reference
       Region 4nr2 D 432-480 order
 Evidence X-RAY 4nr2 E Reference
       Region 4nr2 E 432-480 order
 Evidence X-RAY 4nr2 F Reference
       Region 4nr2 F 432-433 disorder
       Region 4nr2 F 434-480 order
 Evidence X-RAY 4nr2 G Reference
       Region 4nr2 G 432-480 order
 Evidence X-RAY 4nr2 H Reference
       Region 4nr2 H 432-480 order
 Evidence NMR 2jo8 A Reference
       Region 2jo8 A 432-480 order
 Evidence NMR 2jo8 B Reference
       Region 2jo8 B 432-480 order
SeqProS verified 354-356 :
       Region 3com A 299-311 disorder
       Region 326-401 disorder
SeqProS verified 368-371 Hetero tetramer : Q9H8S9
       Region 5twh E 368-371 order
       Region 326-401 disorder
Seqphosphorylation
    3-3 Phosphothreonine
    183-183 Phosphothreonine; by autocatalysis
    265-265 Phosphoserine
    320-320 Phosphoserine
    340-340 Phosphothreonine
    367-367 Phosphothreonine
    387-387 Phosphothreonine; by PKB/AKT1
    410-410 Phosphoserine
    414-414 Phosphoserine
    433-433 Phosphotyrosine
Seqacetylation
    1-1 N-acetylmethionine
 
Prediction
DICHOT
Disorder 1-20,311-487
Known Domain 21-310
SCOPe RPS-Blast
     3a7iA 21-304 e-143 d.144.1.0 automated matches
SCOP Hmmer
     2jflA1 27-285 9.8e-93 Protein kinase-like (PK-...
Pfam RPS-Blast
     PF07714 34-277 1e-05 Protein tyrosine kinase
     PF11629 433-480 2e-16 C terminal SARAH domain of ...
Pfam Hmmer
    PF00069 31-281 3.5e-76 Protein kinase domain
    PF11629 433-480 2.1e-28 C terminal SARAH domain of...