SeqProS possible 201-209 The S214 only (2lay) orT202 and S206 (2lax) were phosphorylated. This linker region is disordered in the smad3. (PubMed=12154125)
Hetero dimer : IID00304Complex
SeqProS possible 208-217 The S214 only (2laz) or S210 and S214 (2lb0) were phosphorylated. This linker region is disordered in the smad3. (PubMed=12154125)
Hetero dimer : IID00328Complex
SeqProS verified 454-465 While the C-terminal tail is disordered in the unphosphorylated form, but ordered in the phosphorylated form. This tail interactions make the heterotrimer formation.
Homo trimer :