IDEAL Node

IDEAL

IID00191 E3 ubiquitin-protein ligase UBR5 (Homo sapiens) O95071

:order :disorder :conflict :PDB cluster :ProS :SCOP Domain :Pfam Domain

Network xml

Experiment

2799

fasta

order/disorder by at least rule

disorder by at least rule

order by at least rule

order/disorder by majority rule

Seq 180-230 Hetero dimer : P0CH28

Evidence X-RAY 2qho H Reference

Region 2qho H 180-226 order

Region 2qho H 227-230 disorder

Evidence X-RAY 2qho F Reference

Region 2qho F 180-228 order

Region 2qho F 229-230 disorder

Evidence X-RAY 2qho D Reference

Region 2qho D 180-226 order

Region 2qho D 227-230 disorder

Evidence X-RAY 2qho B Reference

Region 2qho B 180-225 order

Region 2qho B 226-230 disorder

Seq 2393-2453 Monomer :

Evidence X-RAY 1i2t A Reference

Region 1i2t A 2393-2453 order

Seq 2687-2799 Monomer :

Evidence X-RAY 3pt3 B Reference

Region 3pt3 B 2687-2737 order

Region 3pt3 B 2738-2747 disorder

Region 3pt3 B 2748-2792 order

Region 3pt3 B 2793-2799 disorder

Evidence X-RAY 3pt3 A Reference

Region 3pt3 A 2687-2692 disorder

Region 3pt3 A 2693-2737 order

Region 3pt3 A 2738-2749 disorder

Region 3pt3 A 2750-2792 order

Region 3pt3 A 2793-2799 disorder

Seqphosphorylation

2486-2486 Phosphoserine

2484-2484 Phosphoserine

2469-2469 Phosphoserine

2241-2241 Phosphoserine

2289-2289 Phosphoserine

2213-2213 Phosphothreonine

2076-2076 Phosphoserine

2026-2026 Phosphoserine

2030-2030 Phosphothreonine

2028-2028 Phosphoserine

1990-1990 Phosphoserine

1969-1969 Phosphothreonine

1746-1746 Phosphotyrosine

1780-1780 Phosphoserine

1736-1736 Phosphothreonine

1741-1741 Phosphoserine

1549-1549 Phosphoserine

1481-1481 Phosphoserine

1355-1355 Phosphoserine

1375-1375 Phosphoserine

1308-1308 Phosphoserine

1227-1227 Phosphoserine

1135-1135 Phosphothreonine

808-808 Phosphoserine

928-928 Phosphoserine

1018-1018 Phosphoserine

1115-1115 Phosphothreonine

352-352 Phosphoserine

578-578 Phosphoserine

612-612 Phosphoserine

637-637 Phosphothreonine

327-327 Phosphoserine

110-110 Phosphoserine

2486-2486 Phosphoserine

2469-2469 Phosphoserine

2484-2484 Phosphoserine

2213-2213 Phosphothreonine

2241-2241 Phosphoserine

2289-2289 Phosphoserine

2028-2028 Phosphoserine

2030-2030 Phosphothreonine

2076-2076 Phosphoserine

2026-2026 Phosphoserine

1990-1990 Phosphoserine

1969-1969 Phosphothreonine

1780-1780 Phosphoserine

1746-1746 Phosphotyrosine

1741-1741 Phosphoserine

1736-1736 Phosphothreonine

1549-1549 Phosphoserine

1481-1481 Phosphoserine

1375-1375 Phosphoserine

1355-1355 Phosphoserine

1308-1308 Phosphoserine

1227-1227 Phosphoserine

1135-1135 Phosphothreonine

1115-1115 Phosphothreonine

1018-1018 Phosphoserine

928-928 Phosphoserine

808-808 Phosphoserine

637-637 Phosphothreonine

612-612 Phosphoserine

578-578 Phosphoserine

352-352 Phosphoserine

327-327 Phosphoserine

110-110 Phosphoserine

Seqacetylation

2-2 N-acetylthreonine

Prediction

DICHOT

Disorder 1-34,73-360,497-739,771-2217,2285-2392,2454-2527,2776-2799

Known Domain 35-72,361-496,2218-2284,2393-2453,2528-2775

Cryptic Domain 740-770

SCOPe RPS-Blast

1i2tA 2393-2453 2e-18

3h1dA1 2504-2791 8e-44

SCOP Hmmer

1a12A_ 35-72 0.0001

1a12A_ 361-496 2.4e-12

1nd7A_ 2247-2792 3.1e-72 Hect, E3 ligase catal...

Pfam RPS-Blast

PF11547 180-230 5e-19 E3 ubiquitin ligase EDD

PF02207 1173-1234 5e-08 Putative zinc finger in N...

PF07263 1522-1692 4e-04 Dentin matrix protein 1 (...

PF00658 2393-2449 9e-18 Poly-adenylate binding pr...

PF00632 2499-2798 1e-09 HECT-domain (ubiquitin-tr...

Pfam Hmmer

PF11547 179-230 3e-34 E3 ubiquitin ligase EDD

PF00658 2392-2449 2.3e-23 Poly-adenylate binding p...

PF00632 2501-2798 5.2e-69 HECT-domain (ubiquitin-t...