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IID00203  Protein jagged-1 (Homo sapiens) P78504
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
1218
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 32-335 Homo dimer :
 Evidence X-RAY 4cbz A Reference
       Region 4cbz A 32-55 order
       Region 4cbz A 56-65 disorder
       Region 4cbz A 66-142 order
       Region 4cbz A 143-147 disorder
       Region 4cbz A 148-335 order
 Evidence X-RAY 4cbz B Reference
       Region 4cbz B 32-55 order
       Region 4cbz B 56-65 disorder
       Region 4cbz B 66-142 order
       Region 4cbz B 143-147 disorder
       Region 4cbz B 148-298 order
       Region 4cbz B 299-335 disorder
Seq 32-335 Monomer :
 Evidence X-RAY 4cc0 A Reference
       Region 4cc0 A 32-335 order
 Evidence X-RAY 4cc0 B Reference
       Region 4cc0 B 32-298 order
       Region 4cc0 B 299-335 disorder
 Evidence X-RAY 4cc1 A Reference
       Region 4cc1 A 32-335 order
 Evidence X-RAY 4cc1 B Reference
       Region 4cc1 B 32-335 order
Seq 185-335 Monomer :
 Evidence X-RAY 2vj2 A Reference
       Region 2vj2 A 185-186 disorder
       Region 2vj2 A 187-335 order
 Evidence X-RAY 2vj2 B Reference
       Region 2vj2 B 185-185 disorder
       Region 2vj2 B 186-335 order
Seq 186-335 Hetero trimer :
 Evidence X-RAY 5bo1 A Reference
       Region 5bo1 A 186-335 order
Seq 186-335 Hetero trimer :
 Evidence X-RAY 5bo1 B Reference
       Region 5bo1 B 186-335 order
Seq 252-295 Monomer :
 Evidence NMR 2kb9 A Reference
       Region 2kb9 A 252-295 order
       Region 2kb9 A 252-252 high_rmsd
Seqdisorder 1094-1218
 Evidence NMR Reference
       Region 1094-1218 disorder
Seqdisorder 1094-1218
 Evidence CD Reference
       Region 1094-1218 disorder
Seq 1120-1130 Hetero dimer : Q86YT6
 Evidence X-RAY 4xi7 C Reference
       Region 4xi7 C 1120-1120 disorder
       Region 4xi7 C 1121-1126 order
       Region 4xi7 C 1127-1130 disorder
SeqProS verified 1121-1126 Hetero dimer : Q86YT6
       Region 4xi7 C 1121-1126 order
       Region 1094-1218 disorder
 
Prediction
DICHOT
Disorder 1-31,338-344,411-411,992-1068,1092-1218
Known Domain 32-337,345-410,412-885,1069-1091
Cryptic Domain 886-991
SCOPe RPS-Blast
     5mwbA1 296-335 7e-06 g.3.11.0 automated matches
     1g1tA2 339-375 3e-05 g.3.11.1 Activated protein c (autoprothrombin I...
     1edmB 373-411 1e-08 g.3.11.1 Activated protein c (autoprothrombin II...
     1autL1 409-452 5e-06 g.3.11.1 Activated protein c (autoprothrombin I...
     1edmB 449-485 6e-08 g.3.11.1 Activated protein c (autoprothrombin II...
     1edmB 487-524 2e-10 g.3.11.1 Activated protein c (autoprothrombin II...
     1edmB 525-560 1e-05 g.3.11.1 Activated protein c (autoprothrombin II...
     1edmB 629-666 3e-11 g.3.11.1 Activated protein c (autoprothrombin II...
     5mwbA1 667-702 7e-06 g.3.11.0 automated matches
     1g1tA2 747-779 2e-04 g.3.11.1 Activated protein c (autoprothrombin I...
     1g1tA2 783-821 2e-09 g.3.11.1 Activated protein c (autoprothrombin I...
     1edmB 819-856 3e-09 g.3.11.1 Activated protein c (autoprothrombin II...
SCOP Hmmer
     1haeA_ 297-341 1.3e-09 g.3.11.1 Activated prote...
     2dtgE6 324-458 7.5e-13 g.3.9.1 EGF receptor Cys...
     2dtgE6 438-567 2.1e-17 g.3.9.1 EGF receptor Cys...
     1pfxL2 597-646 2e-06 g.3.11.1 Activated protein...
     1ffmA_ 629-671 6.4e-14 g.3.11.1 Activated prote...
     1dvaL1 663-704 7.2e-12 g.3.11.1 Activated prote...
     1ffmA_ 707-745 1.1e-08 g.3.11.1 Activated prote...
     2dtgE6 731-857 4.9e-13 g.3.9.1 EGF receptor Cys...
     1u5mA_ 855-911 2.1e-07 FnI-like domain
Pfam RPS-Blast
     PF07657 35-106 2e-17 N terminus of Notch ligand
     PF01414 167-229 2e-17 Delta serrate ligand
     PF00008 378-408 4e-04 EGF-like domain
     PF00008 491-519 4e-04 EGF-like domain
     PF00008 633-661 7e-05 EGF-like domain
     PF00008 671-701 7e-05 EGF-like domain
     PF00008 748-777 5e-04 EGF-like domain
Pfam Hmmer
    PF07657 32-107 3.1e-31 N terminus of Notch ligand
    PF01414 167-229 2.9e-28 Delta serrate ligand
    PF00008 300-332 8.1e-09 EGF-like domain
    PF00008 340-370 5.4e-11 EGF-like domain
    PF00008 378-408 1.2e-11 EGF-like domain
    PF07645 412-445 6.4e-08 Calcium-binding EGF domain
    PF00008 456-483 7e-11 EGF-like domain
    PF00008 491-520 1.5e-11 EGF-like domain
    PF00008 529-559 3.9e-09 EGF-like domain
    PF00008 633-663 5.5e-12 EGF-like domain
    PF00008 671-701 5.6e-13 EGF-like domain
    PF00008 748-777 4.5e-12 EGF-like domain
    PF00008 786-815 4e-10 EGF-like domain
    PF12661 829-849 3.4e-08 Human growth factor-like E...