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IID00208  Transducin-like enhancer protein 1 (Homo sapiens) Q04724
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
xml
Experiment
770
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-156 Homo tetramer :
 Evidence X-RAY 4om2 A Reference
       Region 4om2 A 1-19 disorder
       Region 4om2 A 20-131 order
       Region 4om2 A 132-156 disorder
 Evidence X-RAY 4om2 B Reference
       Region 4om2 B 1-21 disorder
       Region 4om2 B 22-128 order
       Region 4om2 B 129-156 disorder
 Evidence X-RAY 4om2 C Reference
       Region 4om2 C 1-20 disorder
       Region 4om2 C 21-130 order
       Region 4om2 C 131-156 disorder
 Evidence X-RAY 4om2 D Reference
       Region 4om2 D 1-20 disorder
       Region 4om2 D 21-128 order
       Region 4om2 D 129-156 disorder
 Evidence X-RAY 4om3 A Reference
       Region 4om3 A 15-18 disorder
       Region 4om3 A 19-135 order
       Region 4om3 A 136-156 disorder
 Evidence X-RAY 4om3 B Reference
       Region 4om3 B 15-19 disorder
       Region 4om3 B 20-131 order
       Region 4om3 B 132-156 disorder
 Evidence X-RAY 4om3 C Reference
       Region 4om3 C 15-18 disorder
       Region 4om3 C 19-135 order
       Region 4om3 C 136-156 disorder
 Evidence X-RAY 4om3 D Reference
       Region 4om3 D 15-19 disorder
       Region 4om3 D 20-133 order
       Region 4om3 D 134-134 disorder
       Region 4om3 D 135-142 order
       Region 4om3 D 143-156 disorder
Seq 443-770 Homo dimer :
 Evidence X-RAY 1gxr A Reference
       Region 1gxr A 443-561 order
       Region 1gxr A 562-563 disorder
       Region 1gxr A 564-770 order
 Evidence X-RAY 1gxr B Reference
       Region 1gxr B 443-450 order
       Region 1gxr B 451-455 disorder
       Region 1gxr B 456-514 order
       Region 1gxr B 515-517 disorder
       Region 1gxr B 518-560 order
       Region 1gxr B 561-563 disorder
       Region 1gxr B 564-685 order
       Region 1gxr B 686-687 disorder
       Region 1gxr B 688-770 order
 Evidence X-RAY 5mwj A Reference
       Region 5mwj A 443-451 order
       Region 5mwj A 452-454 disorder
       Region 5mwj A 455-513 order
       Region 5mwj A 514-518 disorder
       Region 5mwj A 519-559 order
       Region 5mwj A 560-563 disorder
       Region 5mwj A 564-770 order
 Evidence X-RAY 5mwj B Reference
       Region 5mwj B 443-450 order
       Region 5mwj B 451-455 disorder
       Region 5mwj B 456-513 order
       Region 5mwj B 514-517 disorder
       Region 5mwj B 518-559 order
       Region 5mwj B 560-562 disorder
       Region 5mwj B 563-625 order
       Region 5mwj B 626-627 disorder
       Region 5mwj B 628-770 order
Seq 443-770 Hetero trimer :
 Evidence X-RAY 2ce9 C This region binds to a peptide. Reference
       Region 2ce9 C 443-770 order
 Evidence X-RAY 2ce9 D This region binds to a peptide. Reference
       Region 2ce9 D 443-450 order
       Region 2ce9 D 451-455 disorder
       Region 2ce9 D 456-770 order
Seq 443-770 Hetero trimer :
 Evidence X-RAY 2ce9 A This region binds to a peptide. Reference
       Region 2ce9 A 443-770 order
 Evidence X-RAY 2ce9 B This region binds to a peptide. Reference
       Region 2ce9 B 443-770 order
Seq 443-770 Hetero trimer :
 Evidence X-RAY 2ce8 A This region binds to a peptide. Reference
       Region 2ce8 A 443-770 order
 Evidence X-RAY 2ce8 B This region binds to a peptide. Reference
       Region 2ce8 B 443-770 order
Seq 443-770 Hetero trimer :
 Evidence X-RAY 2ce8 C This region binds to a peptide. Reference
       Region 2ce8 C 443-770 order
 Evidence X-RAY 2ce8 D This region binds to a peptide. Reference
       Region 2ce8 D 443-770 order
Seqphosphorylation
    239-239 Phosphoserine
    259-259 Phosphoserine; by CDK1
    263-263 Phosphoserine; by CDK1
    267-267 Phosphoserine; by CDK1
    286-286 Phosphoserine
 
Prediction
DICHOT
Disorder 1-18,136-437
Known Domain 19-135,438-770
SCOPe RPS-Blast
     1gxrA1 443-770 e-135 b.69.4.1 Actin interacting protein 1
SCOP Hmmer
     1gxrA_ 434-768 5.2e-66 WD40 repeat-like
Pfam RPS-Blast
     PF03920 11-133 1e-40 Groucho/TLE N-terminal Q-ric...
     PF15782 290-463 4e-04 Gene regulated by oestrogen...
     PF17005 578-761 4e-11 WD40-like domain
Pfam Hmmer
    PF03920 1-133 1.2e-78 Groucho/TLE N-terminal Q-ric...
    PF00400 578-602 2.8e-05 WD domain, G-beta repeat
    PF00400 608-644 2.6e-06 WD domain, G-beta repeat