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IID00212  Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (Homo sapiens) Q15599
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
337
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 9-90 Hetero dimer : Q9HBW0
 Evidence X-RAY 4p0c A Reference
       Region 4p0c A 9-90 order
Seq 9-91 Monomer :
 Evidence X-RAY 2ocs A Reference
       Region 2ocs A 9-28 order
       Region 2ocs A 29-31 disorder
       Region 2ocs A 32-91 order
Seq 147-228 Monomer :
 Evidence X-RAY 2he4 A Reference
       Region 2he4 A 147-228 order
Seq 310-337 Hetero dimer : IID50114Complex
 Evidence X-RAY 2d11 E Reference
       Region 2d11 E 310-319 disorder
       Region 2d11 E 320-337 order
 Evidence X-RAY 2d11 F Reference
       Region 2d11 F 310-319 disorder
       Region 2d11 F 320-337 order
 Evidence X-RAY 2d11 G Reference
       Region 2d11 G 310-320 disorder
       Region 2d11 G 321-337 order
 Evidence X-RAY 2d11 H Reference
       Region 2d11 H 310-320 disorder
       Region 2d11 H 321-337 order
SeqProS possible 320-337 This region is described to be disordered in the free state. (PubMed=16615918) Hetero dimer : IID50114Complex
       Region 2d11 E 320-337 order
       Region 2d11 F 320-337 order
       Region 2d11 G 321-337 order
       Region 2d11 H 321-337 order
Seqphosphorylation
    130-130 Phosphoserine
    183-183 Phosphoserine
    254-254 Phosphoserine
    269-269 Phosphoserine
    280-280 Phosphoserine
    303-303 Phosphoserine
 
Prediction
DICHOT
Disorder 1-8,92-142,337-337
Known Domain 9-91,143-336
SCOPe RPS-Blast
     4n6xA1 9-96 8e-40 b.36.1.1 Afadin
     4n6xA1 149-236 3e-38 b.36.1.1 Afadin
SCOP Hmmer
     1uitA_ 4-93 6.1e-29 PDZ domain-like
     1uitA_ 145-232 4.6e-28 PDZ domain-like
Pfam RPS-Blast
     PF13180 20-64 9e-06 PDZ domain
     PF17820 35-88 6e-12 PDZ domain
     PF17820 175-228 2e-10 PDZ domain
     PF09007 232-337 2e-31 EBP50, C-terminal
Pfam Hmmer
    PF00595 16-87 4.1e-19 PDZ domain
    PF17820 176-228 1.3e-19 PDZ domain
    PF09007 232-337 4.4e-29 EBP50, C-terminal