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IID00223  E3 ubiquitin-protein ligase SMURF2 (Homo sapiens) Q9HAU4
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
748
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 10-140 Monomer :
 Evidence NMR 2jqz A Reference
       Region 2jqz A 10-140 order
Seq 250-333 Hetero dimer : IID00135Complex
 Evidence NMR 2kxq A Reference
       Region 2kxq A 250-333 order
Seq 297-333 Hetero dimer : IID00135Complex
 Evidence NMR 2ltz A Reference
       Region 2ltz A 297-333 order
 Evidence NMR 2djy A Reference
       Region 2djy A 297-333 order
       Region 2djy A 332-333 high_rmsd
Seq 369-748 Monomer :
 Evidence X-RAY 1zvd A Reference
       Region 1zvd A 369-741 order
       Region 1zvd A 742-748 disorder
 
Prediction
DICHOT
Disorder 1-9,141-156,194-248,334-368,742-748
Known Domain 10-140,157-193,249-333,369-741
SCOPe RPS-Blast
     2nq3A1 9-136 1e-23 b.7.1.1 Domain from cytosolic phospholipase A2
     2itkA1 159-189 3e-12 b.72.1.1 Amyloid beta A4 precursor protein-bin...
     4rexA1 253-286 2e-07 b.72.1.1 Amyloid beta A4 precursor protein-bin...
     4rexA1 295-331 2e-15 b.72.1.1 Amyloid beta A4 precursor protein-bin...
     3h1dA1 371-741 0.0 d.148.1.0 automated matches
SCOP Hmmer
     2nq3A1 12-137 5.6e-25 b.7.1.1 Domain from cytos...
     2e45A1 153-192 2.5e-13 b.72.1.1 Amyloid beta A4...
     1i5hW_ 245-286 4.6e-12 b.72.1.1 Amyloid beta A4...
     1i5hW_ 291-331 6.4e-15 b.72.1.1 Amyloid beta A4...
     1nd7A_ 379-741 1.1e-129 Hect, E3 ligase cataly...
Pfam RPS-Blast
     PF00397 159-188 2e-10 WW domain
     PF00397 253-282 3e-06 WW domain
     PF00397 299-328 5e-08 WW domain
     PF00632 443-745 3e-18 HECT-domain (ubiquitin-tran...
Pfam Hmmer
    PF00168 13-102 5.7e-20 C2 domain
    PF00397 159-188 4.1e-15 WW domain
    PF00397 253-282 1.6e-10 WW domain
    PF00397 299-328 1.7e-12 WW domain
    PF00632 443-747 1.1e-104 HECT-domain (ubiquitin-tr...