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IID00226  E3 ubiquitin-protein ligase AMFR (Homo sapiens) Q9UKV5
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
643
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 313-393 Monomer :
 Evidence NMR 2lxh C Reference
       Region 2lxh C 313-326 disorder
       Region 2lxh C 327-384 order
       Region 2lxh C 384-384 high_rmsd
       Region 2lxh C 385-393 disorder
Seq 313-393,574-600 Hetero trimer : IID00307Complex
 Evidence X-RAY 4lad B Reference
       Region 4lad B 313-338 disorder
       Region 4lad B 339-380 order
       Region 4lad B 381-393 disorder
       Region 4lad B 574-599 order
       Region 4lad B 600-600 disorder
Seq 327-384,574-600 Hetero trimer : IID00307Complex
 Evidence NMR 2lxp B Reference
       Region 2lxp B 574-600 order
 Evidence NMR 2lxp C Reference
       Region 2lxp C 327-384 order
Seq 452-504 Monomer :
 Evidence X-RAY 4g3o A Reference
       Region 4g3o A 456-498 order
 Evidence NMR 2lvn C Reference
       Region 2lvn C 453-504 order
       Region 2lvn C 453-453 high_rmsd
       Region 2lvn C 502-504 high_rmsd
 Evidence NMR 2ejs A Reference
       Region 2ejs A 452-502 order
       Region 2ejs A 452-453 high_rmsd
       Region 2ejs A 502-502 high_rmsd
Seq 453-504 Hetero trimer : P0CG48
 Evidence NMR 2lvp C Reference
       Region 2lvp C 453-504 order
 Evidence NMR 2lvq D Reference
       Region 2lvq D 453-504 order
Seq 453-504 Hetero dimer : P0CG48
 Evidence NMR 2lvo C Reference
       Region 2lvo C 453-504 order
Seq 573-600 Hetero dimer : IID00307Complex
 Evidence X-RAY 3h8k B Reference
       Region 3h8k B 573-600 order
Seq 574-601 Hetero trimer : IID50078Complex
 Evidence X-RAY 3fsh C Reference
       Region 3fsh C 574-579 disorder
       Region 3fsh C 580-600 order
       Region 3fsh C 601-601 disorder
Seqdisorder 579-600
 Evidence NMR Reference
       Region 579-600 disorder
Seq 622-640 Hetero dimer : IID00201Complex
 Evidence X-RAY 3tiw C Reference
       Region 3tiw C 622-639 order
       Region 3tiw C 640-640 disorder
 Evidence X-RAY 3tiw D Reference
       Region 3tiw D 622-640 order
SeqProS verified 573-600 Hetero dimer : IID00307Complex
       Region 3h8k B 573-600 order
       Region 579-600 disorder
SeqProS verified 580-600 Hetero trimer : IID50078Complex
       Region 3fsh C 580-600 order
       Region 579-600 disorder
Seqphosphorylation
    516-516 Phosphoserine
    523-523 Phosphoserine
    542-542 Phosphoserine
 
Prediction
DICHOT
Disorder 1-82,303-326,385-643
Known Domain 83-209,280-302,327-384
Cryptic Domain 210-279
SCOPe RPS-Blast
     2lxhC 327-384 5e-30 g.44.1.0 automated matches
SCOP Hmmer
     1v87A_ 320-385 1.6e-23 RING/U-box
Pfam RPS-Blast
     PF13705 72-295 7e-08 TRC8 N-terminal domain
     PF13923 341-378 2e-10 Zinc finger, C3HC4 type (RI...
     PF02845 459-497 2e-05 CUE domain
     PF18442 574-600 5e-08 E3 gp78 Ube2g2-binding regi...
Pfam Hmmer
    PF13639 339-379 2.4e-15 Ring finger domain
    PF02845 458-497 4.9e-13 CUE domain
    PF18442 574-600 9.7e-20 E3 gp78 Ube2g2-binding reg...