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IID00234
 UniprotP25490
ProteinTranscriptional repressor protein YY1
GeneYY1
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
414
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 199-228 Hetero trimer : IID00562Complex
 Evidence X-RAY 4c5i C Reference
       Region 4c5i C 199-205 disorder
       Region 4c5i C 206-214 order
       Region 4c5i C 215-218 disorder
       Region 4c5i C 219-225 order
       Region 4c5i C 226-228 disorder
Seq 291-414 Monomer :
 Evidence X-RAY 1ubd C Reference
       Region 1ubd C 291-294 disorder
       Region 1ubd C 295-408 order
       Region 1ubd C 409-414 disorder
Seq 352-379 Monomer :
 Evidence NMR 1znm A Reference
       Region 1znm A 352-352 disorder
       Region 1znm A 353-379 order
Seqphosphorylation
    187-187 Phosphoserine
    247-247 Phosphoserine
    378-378 Phosphothreonine
    118-118 Phosphoserine; by CK2
 
Prediction
NeProc
Disorder 1-288,409-414
Order 289-408
ProS 4-11,17-45,55-69,82-117,127-136,143-156,179-187,200-281,409-414
AlphaFold
Disorder 1-271,275-276,278-294,410-414
Order 272-274,277-277,295-409
Pfam Hmmer
PF00096 296-320 6.7e-05
PF00096 325-347 2.7e-06
PF00096 353-377 5.8e-06
PF00096 383-407 1.2e-07
SEG 25-80 ,154-198 ,257-273
Function
Function in SwissProt
Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair; proposed to target the INO80 complex to YY1-responsive elements.