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IID00265  Gelsolin (Homo sapiens) P06396
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
782
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-782 Monomer :
 Evidence X-RAY 3ffn A Reference
       Region 3ffn A 1-49 disorder
       Region 3ffn A 50-285 order
       Region 3ffn A 286-290 disorder
       Region 3ffn A 291-782 order
 Evidence X-RAY 3ffn B Reference
       Region 3ffn B 1-53 disorder
       Region 3ffn B 54-285 order
       Region 3ffn B 286-291 disorder
       Region 3ffn B 292-782 order
Seq 52-176 Hetero tetramer : IID50082Complex,P28289,P29536
 Evidence X-RAY 4z94 G Reference
       Region 4z94 G 52-176 order
Seq 52-176 Hetero trimer : IID50082Complex,P28289
 Evidence X-RAY 4pki G Reference
       Region 4pki G 52-176 order
Seq 52-176 Hetero trimer : IID50082Complex
 Evidence X-RAY 3cjc G Reference
       Region 3cjc G 52-176 order
Seq 52-176 Hetero hexamer : P68139
 Evidence X-RAY 1mdu A Reference
       Region 1mdu A 52-52 disorder
       Region 1mdu A 53-176 order
 Evidence X-RAY 1mdu D Reference
       Region 1mdu D 52-53 disorder
       Region 1mdu D 54-176 order
Seq 52-176 Hetero dimer : P07830
 Evidence X-RAY 3a5l S Reference
       Region 3a5l S 53-53 disorder
       Region 3a5l S 54-176 order
 Evidence X-RAY 3a5m S Reference
       Region 3a5m S 53-53 disorder
       Region 3a5m S 54-176 order
 Evidence X-RAY 3a5n S Reference
       Region 3a5n S 53-53 disorder
       Region 3a5n S 54-176 order
 Evidence X-RAY 3a5o S Reference
       Region 3a5o S 53-53 disorder
       Region 3a5o S 54-176 order
 Evidence X-RAY 1c0f S Reference
       Region 1c0f S 53-176 order
 Evidence X-RAY 1c0g S Reference
       Region 1c0g S 53-176 order
 Evidence X-RAY 3ci5 G Reference
       Region 3ci5 G 52-176 order
 Evidence X-RAY 3cip G Reference
       Region 3cip G 52-176 order
 Evidence X-RAY 1nlv G Reference
       Region 1nlv G 52-53 disorder
       Region 1nlv G 54-176 order
 Evidence X-RAY 1nm1 G Reference
       Region 1nm1 G 52-53 disorder
       Region 1nm1 G 54-176 order
 Evidence X-RAY 1nmd G Reference
       Region 1nmd G 52-53 disorder
       Region 1nmd G 54-176 order
Seq 52-176 Hetero dimer : P60010
 Evidence X-RAY 1yag G Reference
       Region 1yag G 52-176 order
 Evidence X-RAY 1yvn G Reference
       Region 1yvn G 52-176 order
Seq 52-176 Hetero trimer : IID50082Complex,P28289
 Evidence X-RAY 4pkg G Reference
       Region 4pkg G 52-176 order
Seq 52-177 Hetero dimer : P0DM41
 Evidence X-RAY 1d4x G Reference
       Region 1d4x G 52-53 disorder
       Region 1d4x G 54-177 order
Seq 52-179 Hetero trimer : IID00256Complex,IID50082Complex
 Evidence X-RAY 2ff3 A Reference
       Region 2ff3 A 52-54 disorder
       Region 2ff3 A 55-179 order
Seq 52-179 Hetero trimer : IID50082Complex,Q8IRS7
 Evidence X-RAY 2ff6 G Reference
       Region 2ff6 G 52-54 disorder
       Region 2ff6 G 55-179 order
Seq 52-187,196-260 Hetero dimer : IID50082Complex
 Evidence X-RAY 3cjb G Reference
       Region 3cjb G 52-176 order
 Evidence X-RAY 1eqy S Reference
       Region 1eqy S 52-176 order
 Evidence X-RAY 1esv S Reference
       Region 1esv S 52-176 order
 Evidence X-RAY 1p8z G Reference
       Region 1p8z G 52-52 disorder
       Region 1p8z G 53-183 order
       Region 1p8z G 184-187 disorder
 Evidence X-RAY 4pkh E Reference
       Region 4pkh E 52-52 disorder
       Region 4pkh E 53-176 order
       Region 4pkh E 196-260 order
 Evidence X-RAY 4pkh J Reference
       Region 4pkh J 52-176 order
       Region 4pkh J 196-260 order
 Evidence X-RAY 5ubo S Reference
       Region 5ubo S 52-53 disorder
       Region 5ubo S 54-178 order
Seq 52-176,196-260 Hetero trimer : IID50082Complex,P28289
 Evidence X-RAY 4pkh B Reference
       Region 4pkh B 52-53 disorder
       Region 4pkh B 54-176 order
       Region 4pkh B 196-260 order
Seq 52-176,196-260 Hetero trimer : IID50082Complex,P28289
 Evidence X-RAY 4pkh G Reference
       Region 4pkh G 52-176 order
       Region 4pkh G 196-260 order
Seq 52-426 Hetero dimer : IID50082Complex
 Evidence X-RAY 3ffk A Reference
       Region 3ffk A 52-54 disorder
       Region 3ffk A 55-401 order
       Region 3ffk A 402-426 disorder
 Evidence X-RAY 3ffk D Reference
       Region 3ffk D 52-53 disorder
       Region 3ffk D 54-399 order
       Region 3ffk D 400-426 disorder
Seq 53-174 Hetero trimer : IID50082Complex,Q5NBX1
 Evidence X-RAY 3tu5 B Reference
       Region 3tu5 B 53-174 order
Seq 53-176 Hetero dimer : P10992
 Evidence X-RAY 1dej S Reference
       Region 1dej S 53-176 order
Seq 55-179 Hetero trimer : IID50082Complex,P20065
 Evidence X-RAY 1t44 G Reference
       Region 1t44 G 55-179 order
Seq 55-188 Monomer :
 Evidence X-RAY 5dd2 G Reference
       Region 5dd2 G 55-55 disorder
       Region 5dd2 G 56-177 order
       Region 5dd2 G 178-188 disorder
 Evidence X-RAY 5dd2 A Reference
       Region 5dd2 A 55-177 order
       Region 5dd2 A 178-188 disorder
 Evidence NMR 5h3m A Reference
       Region 5h3m A 55-187 order
 Evidence NMR 5h3n A Reference
       Region 5h3n A 55-187 order
       Region 5h3n A 55-55 high_rmsd
       Region 5h3n A 171-187 high_rmsd
Seq 177-196 Monomer :
 Evidence NMR 1sol A Reference
       Region 1sol A 177-196 order
Seq 178-293 Homo dimer :
 Evidence X-RAY 5o2z A Reference
       Region 5o2z A 178-180 disorder
       Region 5o2z A 181-284 order
       Region 5o2z A 285-293 disorder
 Evidence X-RAY 5o2z B Reference
       Region 5o2z B 178-285 order
       Region 5o2z B 286-293 disorder
Seq 178-293 Monomer :
 Evidence X-RAY 5fae A Reference
       Region 5fae A 178-182 order
       Region 5fae A 183-184 disorder
       Region 5fae A 185-284 order
       Region 5fae A 285-293 disorder
 Evidence X-RAY 5faf A Reference
       Region 5faf A 178-287 order
       Region 5faf A 288-293 disorder
 Evidence X-RAY 1kcq A Reference
       Region 1kcq A 185-185 disorder
       Region 1kcq A 186-288 order
Seq 186-288 Hetero dimer :
 Evidence X-RAY 4s10 C Reference
       Region 4s10 C 186-286 order
       Region 4s10 C 287-288 disorder
Seq 186-288 Hetero dimer :
 Evidence X-RAY 4s10 D Reference
       Region 4s10 D 186-186 disorder
       Region 4s10 D 187-288 order
Seq 439-769 Hetero dimer : IID50082Complex
 Evidence X-RAY 1h1v G Reference
       Region 1h1v G 439-482 order
       Region 1h1v G 483-486 disorder
       Region 1h1v G 487-769 order
Seq 439-782 Monomer :
 Evidence X-RAY 2fh1 A Reference
       Region 2fh1 A 439-662 order
       Region 2fh1 A 663-664 disorder
       Region 2fh1 A 665-734 order
       Region 2fh1 A 735-741 disorder
       Region 2fh1 A 742-768 order
       Region 2fh1 A 769-782 disorder
 Evidence X-RAY 2fh1 B Reference
       Region 2fh1 B 439-440 disorder
       Region 2fh1 B 441-481 order
       Region 2fh1 B 482-485 disorder
       Region 2fh1 B 486-768 order
       Region 2fh1 B 769-782 disorder
 Evidence X-RAY 2fh1 C Reference
       Region 2fh1 C 439-440 disorder
       Region 2fh1 C 441-480 order
       Region 2fh1 C 481-486 disorder
       Region 2fh1 C 487-768 order
       Region 2fh1 C 769-782 disorder
 Evidence X-RAY 2fh2 A Reference
       Region 2fh2 A 439-662 order
       Region 2fh2 A 663-664 disorder
       Region 2fh2 A 665-734 order
       Region 2fh2 A 735-741 disorder
       Region 2fh2 A 742-768 order
       Region 2fh2 A 769-782 disorder
 Evidence X-RAY 2fh2 B Reference
       Region 2fh2 B 439-440 disorder
       Region 2fh2 B 441-481 order
       Region 2fh2 B 482-485 disorder
       Region 2fh2 B 486-768 order
       Region 2fh2 B 769-782 disorder
 Evidence X-RAY 2fh2 C Reference
       Region 2fh2 C 439-440 disorder
       Region 2fh2 C 441-480 order
       Region 2fh2 C 481-486 disorder
       Region 2fh2 C 487-768 order
       Region 2fh2 C 769-782 disorder
 Evidence X-RAY 2fh3 A Reference
       Region 2fh3 A 439-662 order
       Region 2fh3 A 663-664 disorder
       Region 2fh3 A 665-734 order
       Region 2fh3 A 735-741 disorder
       Region 2fh3 A 742-768 order
       Region 2fh3 A 769-782 disorder
 Evidence X-RAY 2fh3 B Reference
       Region 2fh3 B 439-440 disorder
       Region 2fh3 B 441-481 order
       Region 2fh3 B 482-485 disorder
       Region 2fh3 B 486-768 order
       Region 2fh3 B 769-782 disorder
 Evidence X-RAY 2fh3 C Reference
       Region 2fh3 C 439-440 disorder
       Region 2fh3 C 441-480 order
       Region 2fh3 C 481-486 disorder
       Region 2fh3 C 487-768 order
       Region 2fh3 C 769-782 disorder
 Evidence X-RAY 2fh4 A Reference
       Region 2fh4 A 439-552 order
       Region 2fh4 A 553-556 disorder
       Region 2fh4 A 557-662 order
       Region 2fh4 A 663-664 disorder
       Region 2fh4 A 665-672 order
       Region 2fh4 A 673-682 disorder
       Region 2fh4 A 683-734 order
       Region 2fh4 A 735-741 disorder
       Region 2fh4 A 742-768 order
       Region 2fh4 A 769-782 disorder
 Evidence X-RAY 2fh4 B Reference
       Region 2fh4 B 439-440 disorder
       Region 2fh4 B 441-481 order
       Region 2fh4 B 482-485 disorder
       Region 2fh4 B 486-551 order
       Region 2fh4 B 552-556 disorder
       Region 2fh4 B 557-768 order
       Region 2fh4 B 769-782 disorder
 Evidence X-RAY 2fh4 C Reference
       Region 2fh4 C 439-440 disorder
       Region 2fh4 C 441-480 order
       Region 2fh4 C 481-486 disorder
       Region 2fh4 C 487-552 order
       Region 2fh4 C 553-556 disorder
       Region 2fh4 C 557-768 order
       Region 2fh4 C 769-782 disorder
 Evidence X-RAY 1p8x A Reference
       Region 1p8x A 439-662 order
       Region 1p8x A 663-664 disorder
       Region 1p8x A 665-672 order
       Region 1p8x A 673-682 disorder
       Region 1p8x A 683-734 order
       Region 1p8x A 735-736 disorder
       Region 1p8x A 737-768 order
       Region 1p8x A 769-782 disorder
 Evidence X-RAY 1p8x B Reference
       Region 1p8x B 439-440 disorder
       Region 1p8x B 441-482 order
       Region 1p8x B 483-485 disorder
       Region 1p8x B 486-768 order
       Region 1p8x B 769-782 disorder
 Evidence X-RAY 1p8x C Reference
       Region 1p8x C 439-440 disorder
       Region 1p8x C 441-482 order
       Region 1p8x C 483-486 disorder
       Region 1p8x C 487-768 order
       Region 1p8x C 769-782 disorder
Seqphosphorylation
    86-86 Phosphotyrosine; by SRC; in vitro
    409-409 Phosphotyrosine; by SRC; in vitro
    465-465 Phosphotyrosine; by SRC
    603-603 Phosphotyrosine; by SRC; in vitro
    651-651 Phosphotyrosine; by SRC; in vitro
    742-742 Phosphothreonine
Seqacetylation
    584-584 N6-acetyllysine
 
Prediction
DICHOT
Disorder 1-49
Known Domain 50-782
SCOPe RPS-Blast
     4cbuG 52-176 6e-43 d.109.1.1 Gelsolin
     5fafA1 178-287 2e-39 d.109.1.1 Gelsolin
     1d0nA3 290-410 6e-40 d.109.1.1 Gelsolin
     2fh1A1 439-559 2e-45 d.109.1.1 Gelsolin
     2fh1A2 560-655 1e-34 d.109.1.1 Gelsolin
     2fh1A3 656-768 3e-43 d.109.1.1 Gelsolin
SCOP Hmmer
     1t44G_ 57-196 2.5e-45 d.109.1.1 Gelsolin
     1j72A2 177-281 3.3e-31 d.109.1.1 Gelsolin
     1d0nA3 294-405 3.2e-32 d.109.1.1 Gelsolin
     1d0nA4 424-568 2.9e-40 d.109.1.1 Gelsolin
     1d0nA6 554-656 1.3e-22 d.109.1.1 Gelsolin
     1d0nA6 657-773 6.9e-37 d.109.1.1 Gelsolin
Pfam RPS-Blast
     PF00626 75-151 2e-04 Gelsolin repeat
     PF00626 202-264 2e-11 Gelsolin repeat
     PF00626 318-384 3e-06 Gelsolin repeat
     PF00626 459-530 8e-06 Gelsolin repeat
     PF00626 684-750 8e-08 Gelsolin repeat
Pfam Hmmer
    PF00626 76-158 4.8e-21 Gelsolin repeat
    PF00626 198-270 3.7e-24 Gelsolin repeat
    PF00626 317-389 1e-19 Gelsolin repeat
    PF00626 455-536 4.9e-23 Gelsolin repeat
    PF00626 576-642 3.3e-12 Gelsolin repeat
    PF00626 681-756 2.8e-21 Gelsolin repeat