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IID00296  72 kDa type IV collagenase (Homo sapiens) P08253
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
660
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 30-660 Hetero dimer : P16035
 Evidence X-RAY 1gxd A Reference
       Region 1gxd A 30-450 order
       Region 1gxd A 451-457 disorder
       Region 1gxd A 458-660 order
 Evidence X-RAY 1gxd B Reference
       Region 1gxd B 30-30 disorder
       Region 1gxd B 31-450 order
       Region 1gxd B 451-457 disorder
       Region 1gxd B 458-660 order
Seq 30-660 Monomer :
 Evidence X-RAY 1ck7 A Reference
       Region 1ck7 A 30-30 disorder
       Region 1ck7 A 31-449 order
       Region 1ck7 A 450-460 disorder
       Region 1ck7 A 461-660 order
Seq 32-452 Hetero trimer :
 Evidence X-RAY 1eak B Reference
       Region 1eak B 32-450 order
       Region 1eak B 451-452 disorder
 Evidence X-RAY 1eak D Reference
       Region 1eak D 32-450 order
       Region 1eak D 451-452 disorder
Seq 32-452 Hetero trimer :
 Evidence X-RAY 1eak A Reference
       Region 1eak A 32-452 order
 Evidence X-RAY 1eak C Reference
       Region 1eak C 32-449 order
       Region 1eak C 450-452 disorder
Seq 110-214 Monomer :
 Evidence NMR 1hov A Reference
       Region 1hov A 110-214 order
Seq 110-450 Hetero dimer : IID00294Complex
 Evidence X-RAY 3ayu A Reference
       Region 3ayu A 110-449 order
       Region 3ayu A 450-450 disorder
Seq 115-213,394-449 Hetero dimer :
 Evidence X-RAY 1qib A Reference
       Region 1qib A 115-213 order
       Region 1qib A 394-449 order
Seq 223-282 Monomer :
 Evidence NMR 1ks0 A Reference
       Region 1ks0 A 223-278 order
       Region 1ks0 A 276-278 high_rmsd
       Region 1ks0 A 279-282 disorder
Seq 278-336 Monomer :
 Evidence NMR 1cxw A Reference
       Region 1cxw A 278-336 order
       Region 1cxw A 334-336 high_rmsd
Seq 337-394 Monomer :
 Evidence NMR 1j7m A Reference
       Region 1j7m A 337-394 order
       Region 1j7m A 394-394 high_rmsd
Seq 443-660 Monomer :
 Evidence X-RAY 1gen A Reference
       Region 1gen A 443-460 disorder
       Region 1gen A 461-660 order
 Evidence X-RAY 1rtg A Reference
       Region 1rtg A 451-457 disorder
       Region 1rtg A 458-660 order
 
Prediction
DICHOT
Disorder 1-30
Known Domain 31-660
SCOPe RPS-Blast
     1l6jA1 35-108 2e-20 a.20.1.2 Fibroblast collagenase (MMP-1)
     4r3vA 105-446 1e-58 d.92.1.0 automated matches
     1genA 461-660 3e-61 b.66.1.1 Collagenase (MMP1), C-terminal domain
SCOP Hmmer
     1ck7A6 42-107 7.2e-21 a.20.1.2 Fibroblast colla...
     1g9kA2 88-446 7.5e-40 d.92.1.6 Metalloprotease
     1genA_ 462-660 2.9e-70 b.66.1.1 Collagenase (MM...
Pfam RPS-Blast
     PF00413 118-178,373 4e-10 Matrixin
     PF00040 233-274 5e-12 Fibronectin type II domain
     PF00040 291-332 9e-12 Fibronectin type II domain
     PF00040 349-390 4e-12 Fibronectin type II domain
     PF00045 520-562 1e-04 Hemopexin
     PF00045 568-608 4e-08 Hemopexin
Pfam Hmmer
    PF01471 49-97 9.8e-11 Putative peptidoglycan bindi...
    PF00413 118-446 6.2e-72 Matrixin
    PF00045 475-517 2.2e-11 Hemopexin
    PF00045 520-563 2.9e-14 Hemopexin
    PF00045 568-614 1.1e-18 Hemopexin
    PF00045 618-660 1.5e-08 Hemopexin