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IID00301
 UniprotP31947
Protein14-3-3 protein sigma
GeneSFN
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
248
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-231 Hetero dimer :
 Evidence X-RAY 7b15 A Reference
       Region 7b15 A 1-231 order
Seq 1-231 Hetero tetramer : IID00013Complex
 Evidence X-RAY 4jc3 A Reference
       Region 4jc3 A 1-231 order
 Evidence X-RAY 4jdd A Reference
       Region 4jdd A 1-231 order
Seq 1-231 Hetero dimer :
 Evidence X-RAY 8anb A Reference
       Region 8anb A 1-70 order
       Region 8anb A 71-77 disorder
       Region 8anb A 78-231 order
Seq 1-231 Hetero dimer :
 Evidence X-RAY 8b2i A Reference
       Region 8b2i A 1-231 order
Seq 1-231 Hetero trimer :
 Evidence X-RAY 6fau C Reference
       Region 6fau C 1-70 order
       Region 6fau C 71-77 disorder
       Region 6fau C 78-231 order
 Evidence X-RAY 6fau A Reference
       Region 6fau A 1-70 order
       Region 6fau A 71-77 disorder
       Region 6fau A 78-231 order
Seq 1-231 Hetero trimer :
 Evidence X-RAY 6faw C Reference
       Region 6faw C 1-69 order
       Region 6faw C 70-77 disorder
       Region 6faw C 78-231 order
 Evidence X-RAY 6faw A Reference
       Region 6faw A 1-69 order
       Region 6faw A 70-77 disorder
       Region 6faw A 78-231 order
Seq 1-231 Hetero dimer : IID00853Complex
 Evidence X-RAY 6ylu A Reference
       Region 6ylu A 1-231 order
Seq 1-231 Hetero tetramer : IID00750Complex
 Evidence X-RAY 5okf B Reference
       Region 5okf B 1-71 order
       Region 5okf B 72-77 disorder
       Region 5okf B 78-206 order
       Region 5okf B 207-212 disorder
       Region 5okf B 213-231 order
 Evidence X-RAY 5okf A Reference
       Region 5okf A 1-70 order
       Region 5okf A 71-76 disorder
       Region 5okf A 77-137 order
       Region 5okf A 138-138 disorder
       Region 5okf A 139-208 order
       Region 5okf A 209-209 disorder
       Region 5okf A 210-231 order
Seq 1-231 Hetero dimer : IID00801Complex
 Evidence X-RAY 8adm A Reference
       Region 8adm A 1-231 order
Seq 1-231 Hetero dimer : IID00810Complex
 Evidence X-RAY 6qiu A Reference
       Region 6qiu A 1-231 order
Seq 1-231 Hetero dimer :
 Evidence X-RAY 8c2e A Reference
       Region 8c2e A 1-71 order
       Region 8c2e A 72-74 disorder
       Region 8c2e A 75-137 order
       Region 8c2e A 138-138 disorder
       Region 8c2e A 139-231 order
Seq 1-231 Hetero dimer : IID00883Complex
 Evidence X-RAY 6qdr A Reference
       Region 6qdr A 1-71 order
       Region 6qdr A 72-74 disorder
       Region 6qdr A 75-231 order
 Evidence X-RAY 6qds A Reference
       Region 6qds A 1-136 order
       Region 6qds A 137-138 disorder
       Region 6qds A 139-231 order
Seq 1-231 Hetero tetramer : IID00750Complex
 Evidence X-RAY 5ok9 B Reference
       Region 5ok9 B 1-71 order
       Region 5ok9 B 72-75 disorder
       Region 5ok9 B 76-231 order
 Evidence X-RAY 5ok9 A Reference
       Region 5ok9 A 1-70 order
       Region 5ok9 A 71-77 disorder
       Region 5ok9 A 78-231 order
Seq 1-231 Hetero dimer : IID00882Complex
 Evidence X-RAY 6ghp A Reference
       Region 6ghp A 1-70 order
       Region 6ghp A 71-77 disorder
       Region 6ghp A 78-109 order
       Region 6ghp A 110-111 disorder
       Region 6ghp A 112-136 order
       Region 6ghp A 137-139 disorder
       Region 6ghp A 140-231 order
Seq 1-231 Hetero tetramer : IID00750Complex
 Evidence X-RAY 5lu1 A Reference
       Region 5lu1 A 1-1 disorder
       Region 5lu1 A 2-71 order
       Region 5lu1 A 72-76 disorder
       Region 5lu1 A 77-231 order
 Evidence X-RAY 5lu1 B Reference
       Region 5lu1 B 1-70 order
       Region 5lu1 B 71-77 disorder
       Region 5lu1 B 78-231 order
 Evidence X-RAY 5lu1 E Reference
       Region 5lu1 E 1-71 order
       Region 5lu1 E 72-77 disorder
       Region 5lu1 E 78-231 order
 Evidence X-RAY 5lu1 F Reference
       Region 5lu1 F 1-71 order
       Region 5lu1 F 72-75 disorder
       Region 5lu1 F 76-231 order
 Evidence X-RAY 5lu2 A Reference
       Region 5lu2 A 1-1 disorder
       Region 5lu2 A 2-231 order
 Evidence X-RAY 5lu2 B Reference
       Region 5lu2 B 1-1 disorder
       Region 5lu2 B 2-72 order
       Region 5lu2 B 73-75 disorder
       Region 5lu2 B 76-231 order
Seq 1-231 Hetero dimer : IID00132Complex
 Evidence X-RAY 6yic A Reference
       Region 6yic A 1-71 order
       Region 6yic A 72-75 disorder
       Region 6yic A 76-231 order
Seq 1-231 Hetero tetramer : IID00844Complex
 Evidence X-RAY 5my9 A Reference
       Region 5my9 A 1-231 order
Seq 1-231 Hetero tetramer : IID00292Complex
 Evidence X-RAY 4iea A Reference
       Region 4iea A 1-71 order
       Region 4iea A 72-76 disorder
       Region 4iea A 77-231 order
Seq 1-231 Hetero dimer :
 Evidence X-RAY 8c2f A Reference
       Region 8c2f A 1-71 order
       Region 8c2f A 72-74 disorder
       Region 8c2f A 75-137 order
       Region 8c2f A 138-138 disorder
       Region 8c2f A 139-231 order
Seq 1-231 Hetero dimer : IID00127Complex
 Evidence X-RAY 6yia A Reference
       Region 6yia A 1-71 order
       Region 6yia A 72-73 disorder
       Region 6yia A 74-231 order
Seq 1-231 Hetero dimer :
 Evidence X-RAY 8aze A Reference
       Region 8aze A 1-231 order
Seq 1-231 Hetero dimer : IID00777Complex
 Evidence X-RAY 6fi5 A Reference
       Region 6fi5 A 1-71 order
       Region 6fi5 A 72-77 disorder
       Region 6fi5 A 78-136 order
       Region 6fi5 A 137-138 disorder
       Region 6fi5 A 139-231 order
Seq 1-231 Hetero dimer : IID00897Complex
 Evidence X-RAY 6qdt A Reference
       Region 6qdt A 1-71 order
       Region 6qdt A 72-73 disorder
       Region 6qdt A 74-231 order
Seq 1-231 Hetero octamer : IID00005Complex
 Evidence X-RAY 6yr5 D Reference
       Region 6yr5 D 1-70 order
       Region 6yr5 D 71-76 disorder
       Region 6yr5 D 77-230 order
       Region 6yr5 D 231-231 disorder
 Evidence X-RAY 6yr5 C Reference
       Region 6yr5 C 1-67 order
       Region 6yr5 C 68-77 disorder
       Region 6yr5 C 78-231 order
 Evidence X-RAY 6yr5 B Reference
       Region 6yr5 B 1-69 order
       Region 6yr5 B 70-76 disorder
       Region 6yr5 B 77-231 order
 Evidence X-RAY 6yr5 A Reference
       Region 6yr5 A 1-70 order
       Region 6yr5 A 71-76 disorder
       Region 6yr5 A 77-231 order
Seq 1-231 Hetero dimer :
 Evidence X-RAY 8bz9 A Reference
       Region 8bz9 A 1-231 order
Seq 1-231 Hetero dimer : IID00844Complex
 Evidence X-RAY 5myc A Reference
       Region 5myc A 1-231 order
Seq 1-231 Hetero tetramer : IID00774Complex
 Evidence X-RAY 5om0 B Reference
       Region 5om0 B 1-1 disorder
       Region 5om0 B 2-71 order
       Region 5om0 B 72-77 disorder
       Region 5om0 B 78-108 order
       Region 5om0 B 109-111 disorder
       Region 5om0 B 112-207 order
       Region 5om0 B 208-209 disorder
       Region 5om0 B 210-230 order
       Region 5om0 B 231-231 disorder
 Evidence X-RAY 5om0 A Reference
       Region 5om0 A 1-71 order
       Region 5om0 A 72-76 disorder
       Region 5om0 A 77-231 order
Seq 1-231 Hetero tetramer : IID00750Complex
 Evidence X-RAY 5ok9 F Reference
       Region 5ok9 F 1-70 order
       Region 5ok9 F 71-75 disorder
       Region 5ok9 F 76-231 order
 Evidence X-RAY 5ok9 E Reference
       Region 5ok9 E 1-71 order
       Region 5ok9 E 72-76 disorder
       Region 5ok9 E 77-231 order
Seq 1-231 Hetero dimer :
 Evidence X-RAY 7b13 A Reference
       Region 7b13 A 1-231 order
Seq 1-231 Hetero tetramer : P0DTC9
 Evidence X-RAY 7qip B Reference
       Region 7qip B 1-71 order
       Region 7qip B 72-75 disorder
       Region 7qip B 76-231 order
 Evidence X-RAY 7qip A Reference
       Region 7qip A 1-71 order
       Region 7qip A 72-76 disorder
       Region 7qip A 77-231 order
Seq 1-231 Hetero tetramer : IID00805Complex
 Evidence X-RAY 5oma D Reference
       Region 5oma D 1-1 disorder
       Region 5oma D 2-72 order
       Region 5oma D 73-77 disorder
       Region 5oma D 78-231 order
 Evidence X-RAY 5oma B Reference
       Region 5oma B 1-74 order
       Region 5oma B 75-77 disorder
       Region 5oma B 78-231 order
Seq 1-231 Hetero dimer :
 Evidence X-RAY 6hmt A Reference
       Region 6hmt A 1-231 order
Seq 1-231 Hetero tetramer : IID00845Complex
 Evidence X-RAY 4dat A Reference
       Region 4dat A 1-67 order
       Region 4dat A 68-77 disorder
       Region 4dat A 78-136 order
       Region 4dat A 137-139 disorder
       Region 4dat A 140-231 order
Seq 1-231 Hetero tetramer : IID00750Complex
 Evidence X-RAY 5ltw A Reference
       Region 5ltw A 1-71 order
       Region 5ltw A 72-76 disorder
       Region 5ltw A 77-231 order
 Evidence X-RAY 5ltw B Reference
       Region 5ltw B 1-1 disorder
       Region 5ltw B 2-73 order
       Region 5ltw B 74-77 disorder
       Region 5ltw B 78-231 order
 Evidence X-RAY 5ltw E Reference
       Region 5ltw E 1-72 order
       Region 5ltw E 73-76 disorder
       Region 5ltw E 77-231 order
 Evidence X-RAY 5ltw F Reference
       Region 5ltw F 1-71 order
       Region 5ltw F 72-74 disorder
       Region 5ltw F 75-231 order
 Evidence X-RAY 5ltw I Reference
       Region 5ltw I 1-231 order
 Evidence X-RAY 5ltw J Reference
       Region 5ltw J 1-71 order
       Region 5ltw J 72-74 disorder
       Region 5ltw J 75-231 order
Seq 1-231 Hetero dimer : IID00292Complex
 Evidence X-RAY 8a68 A Reference
       Region 8a68 A 1-231 order
 Evidence X-RAY 8a6f A Reference
       Region 8a6f A 1-231 order
 Evidence X-RAY 8a6h A Reference
       Region 8a6h A 1-231 order
 Evidence X-RAY 8atr A Reference
       Region 8atr A 1-231 order
 Evidence X-RAY 8ats A Reference
       Region 8ats A 1-231 order
 Evidence X-RAY 8av0 A Reference
       Region 8av0 A 1-231 order
Seq 1-231 Hetero tetramer : IID00882Complex
 Evidence X-RAY 3p1n A Reference
       Region 3p1n A 1-231 order
 Evidence X-RAY 3p1o A Reference
       Region 3p1o A 1-231 order
 Evidence X-RAY 3p1p A Reference
       Region 3p1p A 1-231 order
 Evidence X-RAY 3p1q A Reference
       Region 3p1q A 1-231 order
 Evidence X-RAY 3p1r A Reference
       Region 3p1r A 1-231 order
 Evidence X-RAY 3p1s A Reference
       Region 3p1s A 1-231 order
 Evidence X-RAY 3smk A Reference
       Region 3smk A 1-70 order
       Region 3smk A 71-77 disorder
       Region 3smk A 78-208 order
       Region 3smk A 209-212 disorder
       Region 3smk A 213-231 order
 Evidence X-RAY 3sml A Reference
       Region 3sml A 1-231 order
 Evidence X-RAY 3smm A Reference
       Region 3smm A 1-231 order
 Evidence X-RAY 3smn A Reference
       Region 3smn A 1-231 order
 Evidence X-RAY 3smo A Reference
       Region 3smo A 1-231 order
 Evidence X-RAY 3sp5 A Reference
       Region 3sp5 A 1-231 order
 Evidence X-RAY 3spr A Reference
       Region 3spr A 1-231 order
 Evidence X-RAY 3ux0 A Reference
       Region 3ux0 A 1-70 order
       Region 3ux0 A 71-77 disorder
       Region 3ux0 A 78-231 order
 Evidence X-RAY 4fr3 A Reference
       Region 4fr3 A 1-70 order
       Region 4fr3 A 71-76 disorder
       Region 4fr3 A 77-77 order
       Region 4fr3 A 79-231 order
Seq 1-231 Hetero tetramer : P0DTC9
 Evidence X-RAY 7qik B Reference
       Region 7qik B 1-70 order
       Region 7qik B 71-77 disorder
       Region 7qik B 78-231 order
 Evidence X-RAY 7qik A Reference
       Region 7qik A 1-1 disorder
       Region 7qik A 2-69 order
       Region 7qik A 70-77 disorder
       Region 7qik A 78-231 order
Seq 1-231 Hetero dimer : IID00318Complex
 Evidence X-RAY 6zcj A Reference
       Region 6zcj A 1-231 order
Seq 1-231 Hetero tetramer : IID00363Complex
 Evidence X-RAY 4qli A Reference
       Region 4qli A 1-231 order
Seq 1-231 Hetero dimer : IID00057Complex
 Evidence X-RAY 6xxc A Reference
       Region 6xxc A 1-231 order
 Evidence X-RAY 6xy5 A Reference
       Region 6xy5 A 1-231 order
 Evidence X-RAY 6y18 A Reference
       Region 6y18 A 1-231 order
 Evidence X-RAY 6y1d A Reference
       Region 6y1d A 1-231 order
 Evidence X-RAY 6y3w A Reference
       Region 6y3w A 1-231 order
 Evidence X-RAY 8b4q A Reference
       Region 8b4q A 1-231 order
 Evidence X-RAY 8bjg A Reference
       Region 8bjg A 1-231 order
 Evidence X-RAY 8bjn A Reference
       Region 8bjn A 1-71 order
       Region 8bjn A 72-73 disorder
       Region 8bjn A 74-231 order
 Evidence X-RAY 8bm5 A Reference
       Region 8bm5 A 1-231 order
Seq 1-231 Hetero tetramer : IID00750Complex
 Evidence X-RAY 5okf D Reference
       Region 5okf D 1-70 order
       Region 5okf D 71-77 disorder
       Region 5okf D 78-206 order
       Region 5okf D 207-212 disorder
       Region 5okf D 213-231 order
 Evidence X-RAY 5okf C Reference
       Region 5okf C 1-71 order
       Region 5okf C 72-76 disorder
       Region 5okf C 77-208 order
       Region 5okf C 209-212 disorder
       Region 5okf C 213-231 order
Seq 1-231 Hetero octamer : IID00163Complex
 Evidence X-RAY 6yr6 G Reference
       Region 6yr6 G 1-67 order
       Region 6yr6 G 68-77 disorder
       Region 6yr6 G 78-231 order
 Evidence X-RAY 6yr6 E Reference
       Region 6yr6 E 1-69 order
       Region 6yr6 E 70-76 disorder
       Region 6yr6 E 77-231 order
 Evidence X-RAY 6yr6 C Reference
       Region 6yr6 C 1-69 order
       Region 6yr6 C 70-76 disorder
       Region 6yr6 C 77-231 order
 Evidence X-RAY 6yr6 A Reference
       Region 6yr6 A 1-73 order
       Region 6yr6 A 74-77 disorder
       Region 6yr6 A 78-231 order
Seq 1-231 Hetero octamer : IID00805Complex
 Evidence X-RAY 6t5f D Reference
       Region 6t5f D 1-69 order
       Region 6t5f D 70-75 disorder
       Region 6t5f D 76-231 order
 Evidence X-RAY 6t5f C Reference
       Region 6t5f C 1-231 order
 Evidence X-RAY 6t5f B Reference
       Region 6t5f B 1-71 order
       Region 6t5f B 72-75 disorder
       Region 6t5f B 76-231 order
 Evidence X-RAY 6t5f A Reference
       Region 6t5f A 1-231 order
Seq 1-231 Hetero tetramer : IID00777Complex
 Evidence X-RAY 4y32 A Reference
       Region 4y32 A 1-137 order
       Region 4y32 A 138-138 disorder
       Region 4y32 A 139-231 order
 Evidence X-RAY 4y32 B Reference
       Region 4y32 B 1-137 order
       Region 4y32 B 138-138 disorder
       Region 4y32 B 139-231 order
 Evidence X-RAY 4y3b A Reference
       Region 4y3b A 1-70 order
       Region 4y3b A 71-76 disorder
       Region 4y3b A 77-137 order
       Region 4y3b A 138-138 disorder
       Region 4y3b A 139-231 order
 Evidence X-RAY 4y3b B Reference
       Region 4y3b B 1-70 order
       Region 4y3b B 71-71 disorder
       Region 4y3b B 72-72 order
       Region 4y3b B 73-73 disorder
       Region 4y3b B 74-231 order
 Evidence X-RAY 4y5i A Reference
       Region 4y5i A 1-70 order
       Region 4y5i A 71-77 disorder
       Region 4y5i A 78-109 order
       Region 4y5i A 110-111 disorder
       Region 4y5i A 112-231 order
 Evidence X-RAY 4y5i B Reference
       Region 4y5i B 1-69 order
       Region 4y5i B 70-75 disorder
       Region 4y5i B 76-76 order
       Region 4y5i B 77-77 disorder
       Region 4y5i B 78-230 order
       Region 4y5i B 231-231 disorder
 Evidence X-RAY 6fbw A Reference
       Region 6fbw A 1-71 order
       Region 6fbw A 72-77 disorder
       Region 6fbw A 78-136 order
       Region 6fbw A 137-139 disorder
       Region 6fbw A 140-231 order
 Evidence X-RAY 6fbw C Reference
       Region 6fbw C 1-70 order
       Region 6fbw C 71-77 disorder
       Region 6fbw C 78-209 order
       Region 6fbw C 210-211 disorder
       Region 6fbw C 212-231 order
Seq 1-231 Hetero dimer :
 Evidence X-RAY 8b5p A Reference
       Region 8b5p A 1-231 order
Seq 1-231 Hetero tetramer : IID00845Complex
 Evidence X-RAY 4dau A Reference
       Region 4dau A 1-67 order
       Region 4dau A 68-77 disorder
       Region 4dau A 78-136 order
       Region 4dau A 137-139 disorder
       Region 4dau A 140-231 order
Seq 1-231 Hetero dimer : IID00783Complex
 Evidence X-RAY 6xwd A Reference
       Region 6xwd A 1-231 order
Seq 1-231 Hetero dimer : IID00057Complex
 Evidence X-RAY 6y58 A Reference
       Region 6y58 A 1-231 order
Seq 1-231 Hetero tetramer : IID00005Complex
 Evidence X-RAY 6yr7 B Reference
       Region 6yr7 B 1-71 order
       Region 6yr7 B 72-76 disorder
       Region 6yr7 B 77-231 order
 Evidence X-RAY 6yr7 A Reference
       Region 6yr7 A 1-71 order
       Region 6yr7 A 72-76 disorder
       Region 6yr7 A 77-231 order
Seq 1-231 Hetero tetramer : IID00777Complex
 Evidence X-RAY 4fl5 A Reference
       Region 4fl5 A 1-70 order
       Region 4fl5 A 71-76 disorder
       Region 4fl5 A 77-231 order
 Evidence X-RAY 4fl5 B Reference
       Region 4fl5 B 1-70 order
       Region 4fl5 B 71-77 disorder
       Region 4fl5 B 78-231 order
 Evidence X-RAY 5hf3 A Reference
       Region 5hf3 A 1-71 order
       Region 5hf3 A 72-72 disorder
       Region 5hf3 A 73-73 order
       Region 5hf3 A 74-76 disorder
       Region 5hf3 A 77-136 order
       Region 5hf3 A 137-137 disorder
       Region 5hf3 A 138-231 order
Seq 1-231 Hetero dimer : IID00464Complex
 Evidence X-RAY 8a62 A Reference
       Region 8a62 A 1-231 order
 Evidence X-RAY 8a65 A Reference
       Region 8a65 A 1-231 order
Seq 1-231 Hetero trimer :
 Evidence X-RAY 6fby C Reference
       Region 6fby C 1-69 order
       Region 6fby C 70-77 disorder
       Region 6fby C 78-231 order
 Evidence X-RAY 6fby A Reference
       Region 6fby A 1-69 order
       Region 6fby A 70-77 disorder
       Region 6fby A 78-231 order
Seq 1-231 Hetero dimer :
 Evidence X-RAY 6hn2 A Reference
       Region 6hn2 A 1-231 order
Seq 1-231 Hetero tetramer : IID00874Complex
 Evidence X-RAY 5n5t A Reference
       Region 5n5t A 1-71 order
       Region 5n5t A 72-77 disorder
       Region 5n5t A 78-136 order
       Region 5n5t A 137-138 disorder
       Region 5n5t A 139-231 order
 Evidence X-RAY 5n5w A Reference
       Region 5n5w A 1-70 order
       Region 5n5w A 71-77 disorder
       Region 5n5w A 78-231 order
 Evidence X-RAY 5n75 A Reference
       Region 5n75 A 1-71 order
       Region 5n75 A 72-73 disorder
       Region 5n75 A 74-231 order
Seq 1-231 Hetero dimer : IID90045Complex
 Evidence X-RAY 6w0l A Reference
       Region 6w0l A 1-231 order
Seq 1-231 Hetero tetramer : IID00292Complex
 Evidence X-RAY 3iqj A Reference
       Region 3iqj A 1-231 order
 Evidence X-RAY 3iqu A Reference
       Region 3iqu A 1-231 order
 Evidence X-RAY 3iqv A Reference
       Region 3iqv A 1-231 order
 Evidence X-RAY 3o8i A Reference
       Region 3o8i A 1-67 order
       Region 3o8i A 68-77 disorder
       Region 3o8i A 78-136 order
       Region 3o8i A 137-139 disorder
       Region 3o8i A 140-208 order
       Region 3o8i A 209-211 disorder
       Region 3o8i A 212-231 order
Seq 1-231 Hetero tetramer : IID00805Complex
 Evidence X-RAY 6t5h B Reference
       Region 6t5h B 1-231 order
 Evidence X-RAY 6t5h A Reference
       Region 6t5h A 1-70 order
       Region 6t5h A 71-76 disorder
       Region 6t5h A 77-231 order
Seq 1-231 Hetero trimer :
 Evidence X-RAY 6fav C Reference
       Region 6fav C 1-69 order
       Region 6fav C 70-77 disorder
       Region 6fav C 78-231 order
 Evidence X-RAY 6fav A Reference
       Region 6fav A 1-70 order
       Region 6fav A 71-77 disorder
       Region 6fav A 78-231 order
Seq 1-231 Hetero tetramer : IID00851Complex
 Evidence X-RAY 6fbb A Reference
       Region 6fbb A 1-71 order
       Region 6fbb A 72-72 disorder
       Region 6fbb A 73-136 order
       Region 6fbb A 137-139 disorder
       Region 6fbb A 140-231 order
 Evidence X-RAY 6fcp A Reference
       Region 6fcp A 1-71 order
       Region 6fcp A 72-72 disorder
       Region 6fcp A 73-136 order
       Region 6fcp A 137-139 disorder
       Region 6fcp A 140-231 order
Seq 1-231 Hetero octamer : Q16613
 Evidence X-RAY 6t80 D Reference
       Region 6t80 D 1-69 order
       Region 6t80 D 70-76 disorder
       Region 6t80 D 77-207 order
       Region 6t80 D 208-208 disorder
       Region 6t80 D 209-231 order
 Evidence X-RAY 6t80 C Reference
       Region 6t80 C 1-69 order
       Region 6t80 C 70-77 disorder
       Region 6t80 C 78-206 order
       Region 6t80 C 207-211 disorder
       Region 6t80 C 212-231 order
 Evidence X-RAY 6t80 B Reference
       Region 6t80 B 1-1 disorder
       Region 6t80 B 2-70 order
       Region 6t80 B 71-74 disorder
       Region 6t80 B 75-231 order
 Evidence X-RAY 6t80 A Reference
       Region 6t80 A 1-76 order
       Region 6t80 A 77-78 disorder
       Region 6t80 A 79-231 order
Seq 1-231 Hetero dimer : Q9NTG7
 Evidence X-RAY 8anc A Reference
       Region 8anc A 1-231 order
Seq 1-231 Hetero dimer : IID00113Complex
 Evidence X-RAY 6yib A Reference
       Region 6yib A 1-71 order
       Region 6yib A 72-75 disorder
       Region 6yib A 76-231 order
Seq 1-231 Hetero tetramer : IID00750Complex
 Evidence X-RAY 5ok9 F Reference
       Region 5ok9 F 1-70 order
       Region 5ok9 F 71-75 disorder
       Region 5ok9 F 76-231 order
 Evidence X-RAY 5ok9 E Reference
       Region 5ok9 E 1-71 order
       Region 5ok9 E 72-76 disorder
       Region 5ok9 E 77-231 order
Seq 1-231 Hetero dimer : IID00304Complex
 Evidence X-RAY 3mhr A Reference
       Region 3mhr A 1-231 order
 Evidence X-RAY 6g6x A Reference
       Region 6g6x A 1-231 order
 Evidence X-RAY 6g8i A Reference
       Region 6g8i A 1-231 order
 Evidence X-RAY 6g8j A Reference
       Region 6g8j A 1-231 order
 Evidence X-RAY 6g8k A Reference
       Region 6g8k A 1-231 order
 Evidence X-RAY 6g8l A Reference
       Region 6g8l A 1-231 order
 Evidence X-RAY 6g8p A Reference
       Region 6g8p A 1-231 order
 Evidence X-RAY 6g8q A Reference
       Region 6g8q A 1-231 order
 Evidence X-RAY 7o07 A Reference
       Region 7o07 A 1-71 order
       Region 7o07 A 72-73 disorder
       Region 7o07 A 74-231 order
Seq 1-231 Hetero dimer :
 Evidence X-RAY 8byg A Reference
       Region 8byg A 1-231 order
Seq 1-248 Hetero dimer : IID00295Complex
 Evidence X-RAY 7obg A Reference
       Region 7obg A 1-231 order
       Region 7obg A 232-248 disorder
 Evidence X-RAY 7obh A Reference
       Region 7obh A 1-231 order
       Region 7obh A 232-248 disorder
Seq 1-248 Hetero tetramer :
 Evidence X-RAY 1ywt B Reference
       Region 1ywt B 1-69 order
       Region 1ywt B 70-78 disorder
       Region 1ywt B 79-231 order
       Region 1ywt B 232-248 disorder
 Evidence X-RAY 1ywt A Reference
       Region 1ywt A 1-70 order
       Region 1ywt A 71-78 disorder
       Region 1ywt A 79-231 order
       Region 1ywt A 232-248 disorder
Seq 1-248 Hetero dimer : IID00522Complex
 Evidence X-RAY 6y3s A Reference
       Region 6y3s A 1-207 order
       Region 6y3s A 208-208 disorder
       Region 6y3s A 209-231 order
       Region 6y3s A 232-248 disorder
Seq 1-248 Hetero dimer : IID00866Complex
 Evidence X-RAY 6y8a A Reference
       Region 6y8a A 1-231 order
       Region 6y8a A 232-248 disorder
Seq 1-248 Hetero tetramer : IID00015Complex
 Evidence X-RAY 3lw1 A Reference
       Region 3lw1 A 1-137 order
       Region 3lw1 A 138-138 disorder
       Region 3lw1 A 139-231 order
       Region 3lw1 A 232-248 disorder
Seq 1-248 Hetero dimer : IID00458Complex
 Evidence X-RAY 6y8e A Reference
       Region 6y8e A 1-71 order
       Region 6y8e A 72-77 disorder
       Region 6y8e A 78-231 order
       Region 6y8e A 232-248 disorder
Seq 1-248 Hetero tetramer : IID00464Complex
 Evidence X-RAY 6qzs B Reference
       Region 6qzs B 1-71 order
       Region 6qzs B 72-76 disorder
       Region 6qzs B 77-231 order
       Region 6qzs B 232-248 disorder
 Evidence X-RAY 6qzs A Reference
       Region 6qzs A 1-71 order
       Region 6qzs A 72-76 disorder
       Region 6qzs A 77-231 order
       Region 6qzs A 232-248 disorder
Seq 1-248 Hetero dimer : IID00823Complex
 Evidence X-RAY 6y44 A Reference
       Region 6y44 A 1-70 order
       Region 6y44 A 71-77 disorder
       Region 6y44 A 78-137 order
       Region 6y44 A 138-138 disorder
       Region 6y44 A 139-231 order
       Region 6y44 A 232-248 disorder
Seq 1-248 Homo dimer :
 Evidence X-RAY 1yz5 A Reference
       Region 1yz5 A 1-70 order
       Region 1yz5 A 71-77 disorder
       Region 1yz5 A 78-209 order
       Region 1yz5 A 210-212 disorder
       Region 1yz5 A 213-233 order
       Region 1yz5 A 234-248 disorder
 Evidence X-RAY 1yz5 B Reference
       Region 1yz5 B 1-1 disorder
       Region 1yz5 B 2-71 order
       Region 1yz5 B 72-73 disorder
       Region 1yz5 B 74-232 order
       Region 1yz5 B 233-248 disorder
 Evidence X-RAY 3t0l A Reference
       Region 3t0l A 1-70 order
       Region 3t0l A 71-76 disorder
       Region 3t0l A 77-231 order
 Evidence X-RAY 3t0m A Reference
       Region 3t0m A 1-70 order
       Region 3t0m A 71-76 disorder
       Region 3t0m A 77-231 order
 Evidence X-RAY 3u9x A Reference
       Region 3u9x A 1-70 order
       Region 3u9x A 71-77 disorder
       Region 3u9x A 78-231 order
 Evidence X-RAY 4dhm A Reference
       Region 4dhm A 1-70 order
       Region 4dhm A 71-77 disorder
       Region 4dhm A 78-231 order
 Evidence X-RAY 4dhn A Reference
       Region 4dhn A 1-70 order
       Region 4dhn A 71-77 disorder
       Region 4dhn A 78-231 order
 Evidence X-RAY 4dho A Reference
       Region 4dho A 1-70 order
       Region 4dho A 71-77 disorder
       Region 4dho A 78-231 order
 Evidence X-RAY 4dhp A Reference
       Region 4dhp A 1-70 order
       Region 4dhp A 71-77 disorder
       Region 4dhp A 78-231 order
 Evidence X-RAY 4dhq A Reference
       Region 4dhq A 1-70 order
       Region 4dhq A 71-74 disorder
       Region 4dhq A 75-231 order
 Evidence X-RAY 4dhr A Reference
       Region 4dhr A 1-70 order
       Region 4dhr A 71-77 disorder
       Region 4dhr A 78-231 order
 Evidence X-RAY 4dhs A Reference
       Region 4dhs A 1-70 order
       Region 4dhs A 71-77 disorder
       Region 4dhs A 78-231 order
 Evidence X-RAY 4dht A Reference
       Region 4dht A 1-70 order
       Region 4dht A 71-77 disorder
       Region 4dht A 78-231 order
 Evidence X-RAY 4dhu A Reference
       Region 4dhu A 1-70 order
       Region 4dhu A 71-77 disorder
       Region 4dhu A 78-231 order
 Evidence X-RAY 5oma A Reference
       Region 5oma A 1-74 order
       Region 5oma A 75-77 disorder
       Region 5oma A 78-231 order
 Evidence X-RAY 5oma C Reference
       Region 5oma C 1-1 disorder
       Region 5oma C 2-72 order
       Region 5oma C 73-75 disorder
       Region 5oma C 76-231 order
Seq 1-248 Hetero dimer :
 Evidence X-RAY 7bm9 A Reference
       Region 7bm9 A 1-231 order
       Region 7bm9 A 232-248 disorder
Seq 1-248 Hetero dimer : IID00803Complex
 Evidence X-RAY 6y8b A Reference
       Region 6y8b A 1-71 order
       Region 6y8b A 72-77 disorder
       Region 6y8b A 78-231 order
       Region 6y8b A 232-248 disorder
Seq 1-248 Hetero dimer : IID00756Complex
 Evidence X-RAY 7obs A Reference
       Region 7obs A 1-231 order
       Region 7obs A 232-248 disorder
 Evidence X-RAY 7obt A Reference
       Region 7obt A 1-76 order
       Region 7obt A 77-77 disorder
       Region 7obt A 78-231 order
       Region 7obt A 232-248 disorder
Seq 1-248 Hetero dimer : IID00758Complex
 Evidence X-RAY 7nix A Reference
       Region 7nix A 1-72 order
       Region 7nix A 73-76 disorder
       Region 7nix A 77-231 order
       Region 7nix A 232-248 disorder
Seq 1-248 Hetero dimer : IID00049Complex
 Evidence X-RAY 7or8 A Reference
       Region 7or8 A 1-70 order
       Region 7or8 A 71-76 disorder
       Region 7or8 A 77-231 order
       Region 7or8 A 232-248 disorder
 Evidence X-RAY 7org A Reference
       Region 7org A 1-71 order
       Region 7org A 72-76 disorder
       Region 7org A 77-231 order
       Region 7org A 232-248 disorder
 Evidence X-RAY 7orh A Reference
       Region 7orh A 1-70 order
       Region 7orh A 71-77 disorder
       Region 7orh A 78-231 order
       Region 7orh A 232-248 disorder
 Evidence X-RAY 7ors A Reference
       Region 7ors A 1-71 order
       Region 7ors A 72-73 disorder
       Region 7ors A 74-76 order
       Region 7ors A 77-77 disorder
       Region 7ors A 78-231 order
       Region 7ors A 232-248 disorder
 Evidence X-RAY 7ort A Reference
       Region 7ort A 1-71 order
       Region 7ort A 72-77 disorder
       Region 7ort A 78-231 order
       Region 7ort A 232-248 disorder
Seq 1-248 Homo dimer :
 Evidence X-RAY 6tm7 A Reference
       Region 6tm7 A 1-71 order
       Region 6tm7 A 72-76 disorder
       Region 6tm7 A 77-206 order
       Region 6tm7 A 207-213 disorder
       Region 6tm7 A 214-231 order
       Region 6tm7 A 232-248 disorder
 Evidence X-RAY 6tm7 B Reference
       Region 6tm7 B 1-71 order
       Region 6tm7 B 72-76 disorder
       Region 6tm7 B 77-108 order
       Region 6tm7 B 109-110 disorder
       Region 6tm7 B 111-207 order
       Region 6tm7 B 208-213 disorder
       Region 6tm7 B 214-231 order
       Region 6tm7 B 232-248 disorder
Seq 1-248 Hetero dimer :
 Evidence X-RAY 6y3m A Reference
       Region 6y3m A 1-231 order
       Region 6y3m A 232-248 disorder
Seq 1-248 Hetero dimer : IID00829Complex
 Evidence X-RAY 7aog A Reference
       Region 7aog A 1-231 order
       Region 7aog A 232-248 disorder
 Evidence X-RAY 7axn A Reference
       Region 7axn A 1-71 order
       Region 7axn A 72-73 disorder
       Region 7axn A 74-231 order
       Region 7axn A 232-248 disorder
 Evidence X-RAY 7ayf A Reference
       Region 7ayf A 1-70 order
       Region 7ayf A 71-77 disorder
       Region 7ayf A 78-231 order
       Region 7ayf A 232-248 disorder
 Evidence X-RAY 7az1 A Reference
       Region 7az1 A 1-71 order
       Region 7az1 A 72-74 disorder
       Region 7az1 A 75-231 order
       Region 7az1 A 232-248 disorder
 Evidence X-RAY 7az2 A Reference
       Region 7az2 A 1-71 order
       Region 7az2 A 72-76 disorder
       Region 7az2 A 77-231 order
       Region 7az2 A 232-248 disorder
 Evidence X-RAY 7bdp A Reference
       Region 7bdp A 1-70 order
       Region 7bdp A 71-77 disorder
       Region 7bdp A 78-231 order
       Region 7bdp A 232-248 disorder
 Evidence X-RAY 7bdt A Reference
       Region 7bdt A 1-70 order
       Region 7bdt A 71-77 disorder
       Region 7bdt A 78-231 order
       Region 7bdt A 232-248 disorder
 Evidence X-RAY 7bdy A Reference
       Region 7bdy A 1-71 order
       Region 7bdy A 72-76 disorder
       Region 7bdy A 77-231 order
       Region 7bdy A 232-248 disorder
 Evidence X-RAY 7bfw A Reference
       Region 7bfw A 1-71 order
       Region 7bfw A 72-75 disorder
       Region 7bfw A 76-231 order
       Region 7bfw A 232-248 disorder
 Evidence X-RAY 7bg3 A Reference
       Region 7bg3 A 1-71 order
       Region 7bg3 A 72-74 disorder
       Region 7bg3 A 75-231 order
       Region 7bg3 A 232-248 disorder
 Evidence X-RAY 7bgq A Reference
       Region 7bgq A 1-70 order
       Region 7bgq A 71-77 disorder
       Region 7bgq A 78-231 order
       Region 7bgq A 232-248 disorder
 Evidence X-RAY 7bgr A Reference
       Region 7bgr A 1-70 order
       Region 7bgr A 71-77 disorder
       Region 7bgr A 78-231 order
       Region 7bgr A 232-248 disorder
 Evidence X-RAY 7bgv A Reference
       Region 7bgv A 1-70 order
       Region 7bgv A 71-77 disorder
       Region 7bgv A 78-231 order
       Region 7bgv A 232-248 disorder
 Evidence X-RAY 7bgw A Reference
       Region 7bgw A 1-70 order
       Region 7bgw A 71-77 disorder
       Region 7bgw A 78-231 order
       Region 7bgw A 232-248 disorder
 Evidence X-RAY 7nif A Reference
       Region 7nif A 1-70 order
       Region 7nif A 71-77 disorder
       Region 7nif A 78-231 order
       Region 7nif A 232-248 disorder
 Evidence X-RAY 7nig A Reference
       Region 7nig A 1-70 order
       Region 7nig A 71-77 disorder
       Region 7nig A 78-231 order
       Region 7nig A 232-248 disorder
 Evidence X-RAY 7nj6 A Reference
       Region 7nj6 A 1-70 order
       Region 7nj6 A 71-77 disorder
       Region 7nj6 A 78-231 order
       Region 7nj6 A 232-248 disorder
 Evidence X-RAY 7nj8 A Reference
       Region 7nj8 A 1-70 order
       Region 7nj8 A 71-77 disorder
       Region 7nj8 A 78-231 order
       Region 7nj8 A 232-248 disorder
 Evidence X-RAY 7nja A Reference
       Region 7nja A 1-70 order
       Region 7nja A 71-77 disorder
       Region 7nja A 78-231 order
       Region 7nja A 232-248 disorder
 Evidence X-RAY 7nrk A Reference
       Region 7nrk A 1-70 order
       Region 7nrk A 71-77 disorder
       Region 7nrk A 78-231 order
       Region 7nrk A 232-248 disorder
 Evidence X-RAY 7nrl A Reference
       Region 7nrl A 1-70 order
       Region 7nrl A 71-77 disorder
       Region 7nrl A 78-231 order
       Region 7nrl A 232-248 disorder
 Evidence X-RAY 7oq9 A Reference
       Region 7oq9 A 1-70 order
       Region 7oq9 A 71-77 disorder
       Region 7oq9 A 78-231 order
       Region 7oq9 A 232-248 disorder
 Evidence X-RAY 7oqa A Reference
       Region 7oqa A 1-70 order
       Region 7oqa A 71-77 disorder
       Region 7oqa A 78-231 order
       Region 7oqa A 232-248 disorder
 Evidence X-RAY 8c2g A Reference
       Region 8c2g A 1-69 order
       Region 8c2g A 70-77 disorder
       Region 8c2g A 78-137 order
       Region 8c2g A 138-138 disorder
       Region 8c2g A 139-231 order
 Evidence X-RAY 8c3c A Reference
       Region 8c3c A 1-71 order
       Region 8c3c A 72-74 disorder
       Region 8c3c A 75-231 order
Seq 1-248 Hetero dimer : IID00842Complex
 Evidence X-RAY 7nma A Reference
       Region 7nma A 1-71 order
       Region 7nma A 72-73 disorder
       Region 7nma A 74-76 order
       Region 7nma A 77-77 disorder
       Region 7nma A 78-137 order
       Region 7nma A 138-138 disorder
       Region 7nma A 139-231 order
       Region 7nma A 232-248 disorder
 Evidence X-RAY 7nmw A Reference
       Region 7nmw A 1-71 order
       Region 7nmw A 72-74 disorder
       Region 7nmw A 75-136 order
       Region 7nmw A 137-138 disorder
       Region 7nmw A 139-231 order
       Region 7nmw A 232-248 disorder
 Evidence X-RAY 7nmx A Reference
       Region 7nmx A 1-71 order
       Region 7nmx A 72-77 disorder
       Region 7nmx A 78-136 order
       Region 7nmx A 137-138 disorder
       Region 7nmx A 139-231 order
       Region 7nmx A 232-248 disorder
 Evidence X-RAY 7nn2 A Reference
       Region 7nn2 A 1-71 order
       Region 7nn2 A 72-77 disorder
       Region 7nn2 A 78-137 order
       Region 7nn2 A 138-138 disorder
       Region 7nn2 A 139-231 order
       Region 7nn2 A 232-248 disorder
 Evidence X-RAY 7nnd A Reference
       Region 7nnd A 1-71 order
       Region 7nnd A 72-73 disorder
       Region 7nnd A 74-76 order
       Region 7nnd A 77-77 disorder
       Region 7nnd A 78-136 order
       Region 7nnd A 137-138 disorder
       Region 7nnd A 139-231 order
       Region 7nnd A 232-248 disorder
 Evidence X-RAY 7nne A Reference
       Region 7nne A 1-71 order
       Region 7nne A 72-72 disorder
       Region 7nne A 73-76 order
       Region 7nne A 77-77 disorder
       Region 7nne A 78-136 order
       Region 7nne A 137-138 disorder
       Region 7nne A 139-231 order
       Region 7nne A 232-248 disorder
 Evidence X-RAY 7np2 A Reference
       Region 7np2 A 1-71 order
       Region 7np2 A 72-72 disorder
       Region 7np2 A 73-231 order
       Region 7np2 A 232-248 disorder
 Evidence X-RAY 7npb A Reference
       Region 7npb A 1-71 order
       Region 7npb A 72-72 disorder
       Region 7npb A 73-231 order
       Region 7npb A 232-248 disorder
 Evidence X-RAY 7npg A Reference
       Region 7npg A 1-71 order
       Region 7npg A 72-74 disorder
       Region 7npg A 75-231 order
       Region 7npg A 232-248 disorder
 Evidence X-RAY 7oqg A Reference
       Region 7oqg A 1-70 order
       Region 7oqg A 71-77 disorder
       Region 7oqg A 78-136 order
       Region 7oqg A 137-138 disorder
       Region 7oqg A 139-231 order
       Region 7oqg A 232-248 disorder
 Evidence X-RAY 7oqj A Reference
       Region 7oqj A 1-70 order
       Region 7oqj A 71-77 disorder
       Region 7oqj A 78-136 order
       Region 7oqj A 137-138 disorder
       Region 7oqj A 139-231 order
       Region 7oqj A 232-248 disorder
 Evidence X-RAY 7oqs A Reference
       Region 7oqs A 1-70 order
       Region 7oqs A 71-77 disorder
       Region 7oqs A 78-137 order
       Region 7oqs A 138-138 disorder
       Region 7oqs A 139-231 order
       Region 7oqs A 232-248 disorder
 Evidence X-RAY 7oqu A Reference
       Region 7oqu A 1-70 order
       Region 7oqu A 71-77 disorder
       Region 7oqu A 78-137 order
       Region 7oqu A 138-138 disorder
       Region 7oqu A 139-231 order
       Region 7oqu A 232-248 disorder
 Evidence X-RAY 7oqw A Reference
       Region 7oqw A 1-69 order
       Region 7oqw A 70-78 disorder
       Region 7oqw A 79-136 order
       Region 7oqw A 137-138 disorder
       Region 7oqw A 139-231 order
       Region 7oqw A 232-248 disorder
Seq 1-248 Hetero dimer : IID00013Complex
 Evidence X-RAY 6hhp A Reference
       Region 6hhp A 1-231 order
 Evidence X-RAY 6hkb A Reference
       Region 6hkb A 1-231 order
 Evidence X-RAY 6hkf A Reference
       Region 6hkf A 1-231 order
 Evidence X-RAY 6hmu A Reference
       Region 6hmu A 1-231 order
 Evidence X-RAY 6tjm A Reference
       Region 6tjm A 1-70 order
       Region 6tjm A 71-77 disorder
       Region 6tjm A 78-231 order
 Evidence X-RAY 6tl3 A Reference
       Region 6tl3 A 1-71 order
       Region 6tl3 A 72-76 disorder
       Region 6tl3 A 77-109 order
       Region 6tl3 A 110-110 disorder
       Region 6tl3 A 111-137 order
       Region 6tl3 A 138-139 disorder
       Region 6tl3 A 140-231 order
 Evidence X-RAY 7b9m A Reference
       Region 7b9m A 1-231 order
 Evidence X-RAY 7b9r A Reference
       Region 7b9r A 1-231 order
 Evidence X-RAY 7b9t A Reference
       Region 7b9t A 1-231 order
 Evidence X-RAY 7ba3 A Reference
       Region 7ba3 A 1-231 order
 Evidence X-RAY 7ba5 A Reference
       Region 7ba5 A 1-231 order
 Evidence X-RAY 7ba6 A Reference
       Region 7ba6 A 1-231 order
 Evidence X-RAY 7ba7 A Reference
       Region 7ba7 A 1-231 order
 Evidence X-RAY 7ba8 A Reference
       Region 7ba8 A 1-231 order
 Evidence X-RAY 7ba9 A Reference
       Region 7ba9 A 1-231 order
 Evidence X-RAY 7baa A Reference
       Region 7baa A 1-231 order
 Evidence X-RAY 7bab A Reference
       Region 7bab A 1-231 order
 Evidence X-RAY 7nfw A Reference
       Region 7nfw A 1-72 order
       Region 7nfw A 73-77 disorder
       Region 7nfw A 78-231 order
       Region 7nfw A 232-248 disorder
 Evidence X-RAY 7niz A Reference
       Region 7niz A 1-72 order
       Region 7niz A 73-77 disorder
       Region 7niz A 78-231 order
       Region 7niz A 232-248 disorder
 Evidence X-RAY 7opw A Reference
       Region 7opw A 1-70 order
       Region 7opw A 71-77 disorder
       Region 7opw A 78-231 order
       Region 7opw A 232-248 disorder
 Evidence X-RAY 7oq7 A Reference
       Region 7oq7 A 1-70 order
       Region 7oq7 A 71-77 disorder
       Region 7oq7 A 78-231 order
       Region 7oq7 A 232-248 disorder
 Evidence X-RAY 7pwt A Reference
       Region 7pwt A 1-70 order
       Region 7pwt A 71-77 disorder
       Region 7pwt A 78-109 order
       Region 7pwt A 110-111 disorder
       Region 7pwt A 112-231 order
 Evidence X-RAY 7pwz A Reference
       Region 7pwz A 1-70 order
       Region 7pwz A 71-77 disorder
       Region 7pwz A 78-108 order
       Region 7pwz A 109-111 disorder
       Region 7pwz A 112-231 order
 Evidence X-RAY 8afn A Reference
       Region 8afn A 1-231 order
 Evidence X-RAY 8ai0 A Reference
       Region 8ai0 A 1-231 order
 Evidence X-RAY 8alr A Reference
       Region 8alr A 1-231 order
 Evidence X-RAY 8alt A Reference
       Region 8alt A 1-231 order
 Evidence X-RAY 8alv A Reference
       Region 8alv A 1-231 order
 Evidence X-RAY 8alw A Reference
       Region 8alw A 1-231 order
 Evidence X-RAY 8am7 A Reference
       Region 8am7 A 1-231 order
 Evidence X-RAY 8anf A Reference
       Region 8anf A 1-231 order
 Evidence X-RAY 8aoy A Reference
       Region 8aoy A 1-231 order
 Evidence X-RAY 8aps A Reference
       Region 8aps A 1-231 order
 Evidence X-RAY 8aq1 A Reference
       Region 8aq1 A 1-231 order
 Evidence X-RAY 8aqc A Reference
       Region 8aqc A 1-231 order
 Evidence X-RAY 8aqe A Reference
       Region 8aqe A 1-231 order
 Evidence X-RAY 8aqz A Reference
       Region 8aqz A 1-231 order
 Evidence X-RAY 8ar4 A Reference
       Region 8ar4 A 1-231 order
 Evidence X-RAY 8ar5 A Reference
       Region 8ar5 A 1-231 order
 Evidence X-RAY 8arg A Reference
       Region 8arg A 1-231 order
 Evidence X-RAY 8aro A Reference
       Region 8aro A 1-231 order
 Evidence X-RAY 8arq A Reference
       Region 8arq A 1-231 order
 Evidence X-RAY 8arr A Reference
       Region 8arr A 1-71 order
       Region 8arr A 72-74 disorder
       Region 8arr A 75-231 order
 Evidence X-RAY 8arw A Reference
       Region 8arw A 1-231 order
 Evidence X-RAY 8arx A Reference
       Region 8arx A 1-231 order
 Evidence X-RAY 8ary A Reference
       Region 8ary A 1-231 order
 Evidence X-RAY 8arz A Reference
       Region 8arz A 1-231 order
 Evidence X-RAY 8as1 A Reference
       Region 8as1 A 1-231 order
 Evidence X-RAY 8at9 A Reference
       Region 8at9 A 1-231 order
 Evidence X-RAY 8atp A Reference
       Region 8atp A 1-231 order
 Evidence X-RAY 8au2 A Reference
       Region 8au2 A 1-231 order
 Evidence X-RAY 8aus A Reference
       Region 8aus A 1-231 order
 Evidence X-RAY 8auy A Reference
       Region 8auy A 1-231 order
 Evidence X-RAY 8av3 A Reference
       Region 8av3 A 1-231 order
 Evidence X-RAY 8av4 A Reference
       Region 8av4 A 1-231 order
 Evidence X-RAY 8av7 A Reference
       Region 8av7 A 1-231 order
       Region 8av7 A 232-232 disorder
 Evidence X-RAY 8av8 A Reference
       Region 8av8 A 1-70 order
       Region 8av8 A 71-77 disorder
       Region 8av8 A 78-231 order
 Evidence X-RAY 8awg A Reference
       Region 8awg A 1-231 order
 Evidence X-RAY 8axe A Reference
       Region 8axe A 1-231 order
 Evidence X-RAY 8axu A Reference
       Region 8axu A 1-231 order
 Evidence X-RAY 8b39 A Reference
       Region 8b39 A 1-231 order
 Evidence X-RAY 8bwj A Reference
       Region 8bwj A 1-231 order
 Evidence X-RAY 8bwx A Reference
       Region 8bwx A 1-231 order
 Evidence X-RAY 8bwz A Reference
       Region 8bwz A 1-231 order
 Evidence X-RAY 8bx0 A Reference
       Region 8bx0 A 1-231 order
 Evidence X-RAY 8bx3 A Reference
       Region 8bx3 A 1-231 order
 Evidence X-RAY 8bx4 A Reference
       Region 8bx4 A 1-231 order
 Evidence X-RAY 8bxi A Reference
       Region 8bxi A 1-231 order
 Evidence X-RAY 8bxm A Reference
       Region 8bxm A 1-231 order
 Evidence X-RAY 8bxn A Reference
       Region 8bxn A 1-231 order
 Evidence X-RAY 8bxo A Reference
       Region 8bxo A 1-231 order
 Evidence X-RAY 8bxq A Reference
       Region 8bxq A 1-231 order
 Evidence X-RAY 8bxs A Reference
       Region 8bxs A 1-231 order
 Evidence X-RAY 8by9 A Reference
       Region 8by9 A 1-231 order
 Evidence X-RAY 8byb A Reference
       Region 8byb A 1-231 order
 Evidence X-RAY 8byc A Reference
       Region 8byc A 1-231 order
 Evidence X-RAY 8byd A Reference
       Region 8byd A 1-231 order
 Evidence X-RAY 8bye A Reference
       Region 8bye A 1-231 order
 Evidence X-RAY 8byf A Reference
       Region 8byf A 1-231 order
 Evidence X-RAY 8byo A Reference
       Region 8byo A 1-231 order
 Evidence X-RAY 8byy A Reference
       Region 8byy A 1-231 order
 Evidence X-RAY 8byz A Reference
       Region 8byz A 1-231 order
 Evidence X-RAY 8bz0 A Reference
       Region 8bz0 A 1-231 order
 Evidence X-RAY 8bza A Reference
       Region 8bza A 1-231 order
 Evidence X-RAY 8bzb A Reference
       Region 8bzb A 1-231 order
 Evidence X-RAY 8bzw A Reference
       Region 8bzw A 1-231 order
 Evidence X-RAY 8c04 A Reference
       Region 8c04 A 1-231 order
 Evidence X-RAY 8c0k A Reference
       Region 8c0k A 1-231 order
 Evidence X-RAY 8c4f A Reference
       Region 8c4f A 1-231 order
 Evidence X-RAY 8c4g A Reference
       Region 8c4g A 1-231 order
Seq 1-248 Hetero dimer : IID00792Complex
 Evidence X-RAY 6y40 A Reference
       Region 6y40 A 1-71 order
       Region 6y40 A 72-73 disorder
       Region 6y40 A 74-137 order
       Region 6y40 A 138-138 disorder
       Region 6y40 A 139-231 order
       Region 6y40 A 232-248 disorder
Seq 1-248 Hetero dimer : IID00866Complex
 Evidence X-RAY 6y3o A Reference
       Region 6y3o A 1-71 order
       Region 6y3o A 72-72 disorder
       Region 6y3o A 73-99 order
       Region 6y3o A 100-100 disorder
       Region 6y3o A 101-231 order
       Region 6y3o A 232-248 disorder
Seq 1-248 Hetero dimer : IID00871Complex
 Evidence X-RAY 7obx A Reference
       Region 7obx A 1-231 order
       Region 7obx A 232-248 disorder
 Evidence X-RAY 7oby A Reference
       Region 7oby A 1-71 order
       Region 7oby A 72-72 disorder
       Region 7oby A 73-231 order
       Region 7oby A 232-248 disorder
Seq 1-248 Hetero dimer : IID00443Complex
 Evidence X-RAY 7obk A Reference
       Region 7obk A 1-136 order
       Region 7obk A 137-137 disorder
       Region 7obk A 138-231 order
       Region 7obk A 232-248 disorder
 Evidence X-RAY 7obl A Reference
       Region 7obl A 1-71 order
       Region 7obl A 72-72 disorder
       Region 7obl A 73-136 order
       Region 7obl A 137-137 disorder
       Region 7obl A 138-231 order
       Region 7obl A 232-248 disorder
 Evidence X-RAY 8bi7 A Reference
       Region 8bi7 A 1-231 order
Seq 1-248 Hetero dimer : IID00282Complex
 Evidence X-RAY 7ob5 A Reference
       Region 7ob5 A 1-231 order
       Region 7ob5 A 232-248 disorder
 Evidence X-RAY 7ob8 A Reference
       Region 7ob8 A 1-231 order
       Region 7ob8 A 232-248 disorder
Seq 1-248 Monomer :
 Evidence X-RAY 5btv A Reference
       Region 5btv A 1-70 order
       Region 5btv A 71-77 disorder
       Region 5btv A 78-231 order
 Evidence X-RAY 5mxo A Reference
       Region 5mxo A 1-70 order
       Region 5mxo A 71-77 disorder
       Region 5mxo A 78-136 order
       Region 5mxo A 137-138 disorder
       Region 5mxo A 139-209 order
       Region 5mxo A 210-213 disorder
       Region 5mxo A 214-231 order
 Evidence X-RAY 5oeg A Reference
       Region 5oeg A 1-70 order
       Region 5oeg A 71-77 disorder
       Region 5oeg A 78-231 order
 Evidence X-RAY 5oeh A Reference
       Region 5oeh A 1-70 order
       Region 5oeh A 71-76 disorder
       Region 5oeh A 77-231 order
 Evidence X-RAY 6fi4 A Reference
       Region 6fi4 A 1-69 order
       Region 6fi4 A 70-77 disorder
       Region 6fi4 A 78-109 order
       Region 6fi4 A 110-112 disorder
       Region 6fi4 A 113-135 order
       Region 6fi4 A 136-139 disorder
       Region 6fi4 A 140-231 order
 Evidence X-RAY 6qdu A Reference
       Region 6qdu A 1-71 order
       Region 6qdu A 72-74 disorder
       Region 6qdu A 75-136 order
       Region 6qdu A 137-138 disorder
       Region 6qdu A 139-231 order
 Evidence X-RAY 6tch B Reference
       Region 6tch B 1-231 order
 Evidence X-RAY 6tlf A Reference
       Region 6tlf A 1-71 order
       Region 6tlf A 72-76 disorder
       Region 6tlf A 77-207 order
       Region 6tlf A 208-213 disorder
       Region 6tlf A 214-231 order
       Region 6tlf A 232-248 disorder
 Evidence X-RAY 6tlg A Reference
       Region 6tlg A 1-73 order
       Region 6tlg A 74-75 disorder
       Region 6tlg A 76-209 order
       Region 6tlg A 210-211 disorder
       Region 6tlg A 212-231 order
       Region 6tlg A 232-248 disorder
 Evidence X-RAY 6y3v A Reference
       Region 6y3v A 1-71 order
       Region 6y3v A 72-72 disorder
       Region 6y3v A 73-231 order
       Region 6y3v A 232-248 disorder
 Evidence X-RAY 6ye9 A Reference
       Region 6ye9 A 1-231 order
 Evidence X-RAY 7zmu A Reference
       Region 7zmu A 1-231 order
 Evidence X-RAY 7zmw A Reference
       Region 7zmw A 1-231 order
Seq 1-248 Hetero dimer : IID00874Complex
 Evidence X-RAY 5n5r A Reference
       Region 5n5r A 1-71 order
       Region 5n5r A 72-77 disorder
       Region 5n5r A 78-231 order
 Evidence X-RAY 6rhc A Reference
       Region 6rhc A 1-69 order
       Region 6rhc A 70-77 disorder
       Region 6rhc A 78-231 order
 Evidence X-RAY 6rjl A Reference
       Region 6rjl A 1-231 order
       Region 6rjl A 232-248 disorder
 Evidence X-RAY 6rjq A Reference
       Region 6rjq A 1-231 order
       Region 6rjq A 232-248 disorder
 Evidence X-RAY 6rp6 A Reference
       Region 6rp6 A 1-231 order
 Evidence X-RAY 6slw A Reference
       Region 6slw A 1-71 order
       Region 6slw A 72-77 disorder
       Region 6slw A 78-231 order
       Region 6slw A 232-248 disorder
 Evidence X-RAY 6slx A Reference
       Region 6slx A 1-71 order
       Region 6slx A 72-77 disorder
       Region 6slx A 78-231 order
       Region 6slx A 232-248 disorder
Seq 1-248 Hetero hexadecamer : IID00464Complex
 Evidence X-RAY 6qzr H Reference
       Region 6qzr H 1-71 order
       Region 6qzr H 72-76 disorder
       Region 6qzr H 77-231 order
       Region 6qzr H 232-248 disorder
 Evidence X-RAY 6qzr G Reference
       Region 6qzr G 1-70 order
       Region 6qzr G 71-76 disorder
       Region 6qzr G 77-206 order
       Region 6qzr G 207-210 disorder
       Region 6qzr G 211-231 order
       Region 6qzr G 232-248 disorder
 Evidence X-RAY 6qzr F Reference
       Region 6qzr F 1-70 order
       Region 6qzr F 71-75 disorder
       Region 6qzr F 76-231 order
       Region 6qzr F 232-248 disorder
 Evidence X-RAY 6qzr E Reference
       Region 6qzr E 1-70 order
       Region 6qzr E 71-77 disorder
       Region 6qzr E 78-231 order
       Region 6qzr E 232-248 disorder
 Evidence X-RAY 6qzr D Reference
       Region 6qzr D 1-70 order
       Region 6qzr D 71-77 disorder
       Region 6qzr D 78-206 order
       Region 6qzr D 207-214 disorder
       Region 6qzr D 215-229 order
       Region 6qzr D 230-248 disorder
 Evidence X-RAY 6qzr C Reference
       Region 6qzr C 1-70 order
       Region 6qzr C 71-76 disorder
       Region 6qzr C 77-231 order
       Region 6qzr C 232-248 disorder
 Evidence X-RAY 6qzr B Reference
       Region 6qzr B 1-70 order
       Region 6qzr B 71-77 disorder
       Region 6qzr B 78-231 order
       Region 6qzr B 232-248 disorder
 Evidence X-RAY 6qzr A Reference
       Region 6qzr A 1-70 order
       Region 6qzr A 71-76 disorder
       Region 6qzr A 77-206 order
       Region 6qzr A 207-213 disorder
       Region 6qzr A 214-231 order
       Region 6qzr A 232-248 disorder
Seq 1-248 Hetero dimer : IID00015Complex
 Evidence X-RAY 5mhc A Reference
       Region 5mhc A 1-71 order
       Region 5mhc A 72-72 disorder
       Region 5mhc A 73-231 order
 Evidence X-RAY 5moc A Reference
       Region 5moc A 1-70 order
       Region 5moc A 71-77 disorder
       Region 5moc A 78-136 order
       Region 5moc A 137-138 disorder
       Region 5moc A 139-231 order
 Evidence X-RAY 6r5l A Reference
       Region 6r5l A 1-231 order
 Evidence X-RAY 6rjz A Reference
       Region 6rjz A 1-71 order
       Region 6rjz A 72-77 disorder
       Region 6rjz A 78-136 order
       Region 6rjz A 137-138 disorder
       Region 6rjz A 139-231 order
       Region 6rjz A 232-248 disorder
 Evidence X-RAY 6rk8 A Reference
       Region 6rk8 A 1-137 order
       Region 6rk8 A 138-138 disorder
       Region 6rk8 A 139-231 order
       Region 6rk8 A 232-248 disorder
 Evidence X-RAY 6rki A Reference
       Region 6rki A 1-231 order
       Region 6rki A 232-248 disorder
 Evidence X-RAY 6rkk A Reference
       Region 6rkk A 1-137 order
       Region 6rkk A 138-138 disorder
       Region 6rkk A 139-231 order
       Region 6rkk A 232-248 disorder
 Evidence X-RAY 6rkm A Reference
       Region 6rkm A 1-70 order
       Region 6rkm A 71-77 disorder
       Region 6rkm A 78-231 order
       Region 6rkm A 232-248 disorder
 Evidence X-RAY 6rl3 A Reference
       Region 6rl3 A 1-71 order
       Region 6rl3 A 72-76 disorder
       Region 6rl3 A 77-231 order
       Region 6rl3 A 232-248 disorder
 Evidence X-RAY 6rl4 A Reference
       Region 6rl4 A 1-71 order
       Region 6rl4 A 72-77 disorder
       Region 6rl4 A 78-231 order
       Region 6rl4 A 232-248 disorder
 Evidence X-RAY 6rl6 A Reference
       Region 6rl6 A 1-71 order
       Region 6rl6 A 72-77 disorder
       Region 6rl6 A 78-231 order
       Region 6rl6 A 232-248 disorder
 Evidence X-RAY 6rm5 A Reference
       Region 6rm5 A 1-71 order
       Region 6rm5 A 72-77 disorder
       Region 6rm5 A 78-137 order
       Region 6rm5 A 138-138 disorder
       Region 6rm5 A 139-231 order
       Region 6rm5 A 232-248 disorder
 Evidence X-RAY 6rm7 A Reference
       Region 6rm7 A 1-71 order
       Region 6rm7 A 72-73 disorder
       Region 6rm7 A 74-231 order
       Region 6rm7 A 232-248 disorder
 Evidence X-RAY 6rwh A Reference
       Region 6rwh A 1-70 order
       Region 6rwh A 71-77 disorder
       Region 6rwh A 78-136 order
       Region 6rwh A 137-138 disorder
       Region 6rwh A 139-231 order
       Region 6rwh A 232-248 disorder
 Evidence X-RAY 6rwi A Reference
       Region 6rwi A 1-70 order
       Region 6rwi A 71-77 disorder
       Region 6rwi A 78-136 order
       Region 6rwi A 137-138 disorder
       Region 6rwi A 139-231 order
       Region 6rwi A 232-248 disorder
 Evidence X-RAY 6rws A Reference
       Region 6rws A 1-70 order
       Region 6rws A 71-77 disorder
       Region 6rws A 78-137 order
       Region 6rws A 138-138 disorder
       Region 6rws A 139-231 order
       Region 6rws A 232-248 disorder
 Evidence X-RAY 6rwu A Reference
       Region 6rwu A 1-70 order
       Region 6rwu A 71-77 disorder
       Region 6rwu A 78-231 order
       Region 6rwu A 232-248 disorder
 Evidence X-RAY 6rx2 A Reference
       Region 6rx2 A 1-70 order
       Region 6rx2 A 71-77 disorder
       Region 6rx2 A 78-136 order
       Region 6rx2 A 137-139 disorder
       Region 6rx2 A 140-156 order
       Region 6rx2 A 157-157 disorder
       Region 6rx2 A 158-231 order
       Region 6rx2 A 232-248 disorder
 Evidence X-RAY 6s39 A Reference
       Region 6s39 A 1-70 order
       Region 6s39 A 71-77 disorder
       Region 6s39 A 78-136 order
       Region 6s39 A 137-138 disorder
       Region 6s39 A 139-231 order
       Region 6s39 A 232-248 disorder
 Evidence X-RAY 6s3c A Reference
       Region 6s3c A 1-70 order
       Region 6s3c A 71-77 disorder
       Region 6s3c A 78-231 order
       Region 6s3c A 232-248 disorder
 Evidence X-RAY 6s40 A Reference
       Region 6s40 A 1-71 order
       Region 6s40 A 72-75 disorder
       Region 6s40 A 76-231 order
       Region 6s40 A 232-248 disorder
 Evidence X-RAY 6s9q A Reference
       Region 6s9q A 1-70 order
       Region 6s9q A 71-77 disorder
       Region 6s9q A 78-136 order
       Region 6s9q A 137-138 disorder
       Region 6s9q A 139-231 order
       Region 6s9q A 232-248 disorder
 Evidence X-RAY 6sin A Reference
       Region 6sin A 1-70 order
       Region 6sin A 71-77 disorder
       Region 6sin A 78-231 order
 Evidence X-RAY 6sio A Reference
       Region 6sio A 1-70 order
       Region 6sio A 71-77 disorder
       Region 6sio A 78-135 order
       Region 6sio A 136-139 disorder
       Region 6sio A 140-231 order
 Evidence X-RAY 6sip A Reference
       Region 6sip A 1-70 order
       Region 6sip A 71-75 disorder
       Region 6sip A 76-231 order
 Evidence X-RAY 6siq A Reference
       Region 6siq A 1-70 order
       Region 6siq A 71-78 disorder
       Region 6siq A 79-231 order
 Evidence X-RAY 6slv A Reference
       Region 6slv A 1-231 order
Seq 1-248 Hetero dimer :
 Evidence X-RAY 7bmc A Reference
       Region 7bmc A 1-71 order
       Region 7bmc A 72-72 disorder
       Region 7bmc A 73-76 order
       Region 7bmc A 77-77 disorder
       Region 7bmc A 78-231 order
       Region 7bmc A 232-248 disorder
Seq 1-248 Hetero dimer : IID00207Complex
 Evidence X-RAY 6nv2 A Reference
       Region 6nv2 A 1-231 order
 Evidence X-RAY 6qhl A Reference
       Region 6qhl A 1-231 order
       Region 6qhl A 232-248 disorder
 Evidence X-RAY 6yow A Reference
       Region 6yow A 1-70 order
       Region 6yow A 71-74 disorder
       Region 6yow A 75-231 order
 Evidence X-RAY 6yox A Reference
       Region 6yox A 1-231 order
       Region 6yox A 232-248 disorder
 Evidence X-RAY 6yoy A Reference
       Region 6yoy A 1-70 order
       Region 6yoy A 71-75 disorder
       Region 6yoy A 76-231 order
 Evidence X-RAY 6yp2 A Reference
       Region 6yp2 A 1-231 order
 Evidence X-RAY 6yp3 A Reference
       Region 6yp3 A 1-231 order
 Evidence X-RAY 6yp8 A Reference
       Region 6yp8 A 1-231 order
 Evidence X-RAY 6ypl A Reference
       Region 6ypl A 1-231 order
 Evidence X-RAY 6ypy A Reference
       Region 6ypy A 1-231 order
 Evidence X-RAY 6yq2 A Reference
       Region 6yq2 A 1-71 order
       Region 6yq2 A 72-77 disorder
       Region 6yq2 A 78-231 order
 Evidence X-RAY 7bi3 A Reference
       Region 7bi3 A 1-70 order
       Region 7bi3 A 71-74 disorder
       Region 7bi3 A 75-231 order
       Region 7bi3 A 232-248 disorder
 Evidence X-RAY 7biq A Reference
       Region 7biq A 1-70 order
       Region 7biq A 71-74 disorder
       Region 7biq A 75-231 order
       Region 7biq A 232-248 disorder
 Evidence X-RAY 7biw A Reference
       Region 7biw A 1-70 order
       Region 7biw A 71-74 disorder
       Region 7biw A 75-231 order
       Region 7biw A 232-248 disorder
 Evidence X-RAY 7biy A Reference
       Region 7biy A 1-71 order
       Region 7biy A 72-77 disorder
       Region 7biy A 78-231 order
       Region 7biy A 232-248 disorder
 Evidence X-RAY 7bjb A Reference
       Region 7bjb A 1-231 order
       Region 7bjb A 232-248 disorder
 Evidence X-RAY 7bjf A Reference
       Region 7bjf A 1-231 order
       Region 7bjf A 232-248 disorder
 Evidence X-RAY 7bjl A Reference
       Region 7bjl A 1-70 order
       Region 7bjl A 71-74 disorder
       Region 7bjl A 75-231 order
       Region 7bjl A 232-248 disorder
 Evidence X-RAY 7bjw A Reference
       Region 7bjw A 1-70 order
       Region 7bjw A 71-74 disorder
       Region 7bjw A 75-231 order
       Region 7bjw A 232-248 disorder
 Evidence X-RAY 7bkh A Reference
       Region 7bkh A 1-70 order
       Region 7bkh A 71-77 disorder
       Region 7bkh A 78-231 order
       Region 7bkh A 232-248 disorder
 Evidence X-RAY 7nj9 A Reference
       Region 7nj9 A 1-70 order
       Region 7nj9 A 71-77 disorder
       Region 7nj9 A 78-231 order
       Region 7nj9 A 232-248 disorder
 Evidence X-RAY 7njb A Reference
       Region 7njb A 1-71 order
       Region 7njb A 72-77 disorder
       Region 7njb A 78-231 order
       Region 7njb A 232-248 disorder
 Evidence X-RAY 7nk3 A Reference
       Region 7nk3 A 1-71 order
       Region 7nk3 A 72-77 disorder
       Region 7nk3 A 78-231 order
       Region 7nk3 A 232-248 disorder
 Evidence X-RAY 7nk5 A Reference
       Region 7nk5 A 1-71 order
       Region 7nk5 A 72-77 disorder
       Region 7nk5 A 78-231 order
       Region 7nk5 A 232-248 disorder
 Evidence X-RAY 7nla A Reference
       Region 7nla A 1-70 order
       Region 7nla A 71-77 disorder
       Region 7nla A 78-231 order
       Region 7nla A 232-248 disorder
 Evidence X-RAY 7nle A Reference
       Region 7nle A 1-70 order
       Region 7nle A 71-77 disorder
       Region 7nle A 78-231 order
       Region 7nle A 232-248 disorder
 Evidence X-RAY 7nm1 A Reference
       Region 7nm1 A 1-71 order
       Region 7nm1 A 72-77 disorder
       Region 7nm1 A 78-231 order
       Region 7nm1 A 232-248 disorder
 Evidence X-RAY 7nm3 A Reference
       Region 7nm3 A 1-70 order
       Region 7nm3 A 71-77 disorder
       Region 7nm3 A 78-231 order
       Region 7nm3 A 232-248 disorder
 Evidence X-RAY 7nm9 A Reference
       Region 7nm9 A 1-68 order
       Region 7nm9 A 69-77 disorder
       Region 7nm9 A 78-136 order
       Region 7nm9 A 137-139 disorder
       Region 7nm9 A 140-231 order
       Region 7nm9 A 232-248 disorder
 Evidence X-RAY 7nmh A Reference
       Region 7nmh A 1-71 order
       Region 7nmh A 72-77 disorder
       Region 7nmh A 78-231 order
       Region 7nmh A 232-248 disorder
 Evidence X-RAY 7nqp A Reference
       Region 7nqp A 1-70 order
       Region 7nqp A 71-77 disorder
       Region 7nqp A 78-231 order
       Region 7nqp A 232-248 disorder
 Evidence X-RAY 7nr7 A Reference
       Region 7nr7 A 1-70 order
       Region 7nr7 A 71-77 disorder
       Region 7nr7 A 78-231 order
       Region 7nr7 A 232-248 disorder
 Evidence X-RAY 7nsv A Reference
       Region 7nsv A 1-70 order
       Region 7nsv A 71-77 disorder
       Region 7nsv A 78-136 order
       Region 7nsv A 137-138 disorder
       Region 7nsv A 139-231 order
       Region 7nsv A 232-248 disorder
 Evidence X-RAY 7nv4 A Reference
       Region 7nv4 A 1-70 order
       Region 7nv4 A 71-77 disorder
       Region 7nv4 A 78-231 order
 Evidence X-RAY 7nvi A Reference
       Region 7nvi A 1-70 order
       Region 7nvi A 71-77 disorder
       Region 7nvi A 78-231 order
 Evidence X-RAY 7nws A Reference
       Region 7nws A 1-70 order
       Region 7nws A 71-77 disorder
       Region 7nws A 78-231 order
 Evidence X-RAY 7nxs A Reference
       Region 7nxs A 1-70 order
       Region 7nxs A 71-77 disorder
       Region 7nxs A 78-231 order
 Evidence X-RAY 7nxt A Reference
       Region 7nxt A 1-68 order
       Region 7nxt A 69-77 disorder
       Region 7nxt A 78-231 order
 Evidence X-RAY 7nxw A Reference
       Region 7nxw A 1-68 order
       Region 7nxw A 69-77 disorder
       Region 7nxw A 78-231 order
 Evidence X-RAY 7nxy A Reference
       Region 7nxy A 1-70 order
       Region 7nxy A 71-77 disorder
       Region 7nxy A 78-231 order
 Evidence X-RAY 7ny4 A Reference
       Region 7ny4 A 1-70 order
       Region 7ny4 A 71-77 disorder
       Region 7ny4 A 78-231 order
 Evidence X-RAY 7nye A Reference
       Region 7nye A 1-71 order
       Region 7nye A 72-77 disorder
       Region 7nye A 78-231 order
 Evidence X-RAY 7nyf A Reference
       Region 7nyf A 1-71 order
       Region 7nyf A 72-77 disorder
       Region 7nyf A 78-231 order
 Evidence X-RAY 7nyg A Reference
       Region 7nyg A 1-70 order
       Region 7nyg A 71-77 disorder
       Region 7nyg A 78-231 order
 Evidence X-RAY 7nz6 A Reference
       Region 7nz6 A 1-70 order
       Region 7nz6 A 71-77 disorder
       Region 7nz6 A 78-231 order
 Evidence X-RAY 7nzg A Reference
       Region 7nzg A 1-70 order
       Region 7nzg A 71-77 disorder
       Region 7nzg A 78-231 order
 Evidence X-RAY 7nzk A Reference
       Region 7nzk A 1-70 order
       Region 7nzk A 71-77 disorder
       Region 7nzk A 78-231 order
 Evidence X-RAY 7nzv A Reference
       Region 7nzv A 1-70 order
       Region 7nzv A 71-76 disorder
       Region 7nzv A 77-231 order
 Evidence X-RAY 7o34 A Reference
       Region 7o34 A 1-69 order
       Region 7o34 A 70-77 disorder
       Region 7o34 A 78-231 order
 Evidence X-RAY 7o3a A Reference
       Region 7o3a A 1-71 order
       Region 7o3a A 72-77 disorder
       Region 7o3a A 78-231 order
 Evidence X-RAY 7o3f A Reference
       Region 7o3f A 1-70 order
       Region 7o3f A 71-77 disorder
       Region 7o3f A 78-231 order
 Evidence X-RAY 7o3p A Reference
       Region 7o3p A 1-70 order
       Region 7o3p A 71-77 disorder
       Region 7o3p A 78-231 order
 Evidence X-RAY 7o3q A Reference
       Region 7o3q A 1-71 order
       Region 7o3q A 72-77 disorder
       Region 7o3q A 78-231 order
 Evidence X-RAY 7o3r A Reference
       Region 7o3r A 1-70 order
       Region 7o3r A 71-77 disorder
       Region 7o3r A 78-231 order
 Evidence X-RAY 7o3s A Reference
       Region 7o3s A 1-71 order
       Region 7o3s A 72-77 disorder
       Region 7o3s A 78-231 order
 Evidence X-RAY 7o57 A Reference
       Region 7o57 A 1-70 order
       Region 7o57 A 71-77 disorder
       Region 7o57 A 78-231 order
 Evidence X-RAY 7o59 A Reference
       Region 7o59 A 1-70 order
       Region 7o59 A 71-77 disorder
       Region 7o59 A 78-231 order
 Evidence X-RAY 7o5a A Reference
       Region 7o5a A 1-70 order
       Region 7o5a A 71-77 disorder
       Region 7o5a A 78-231 order
 Evidence X-RAY 7o5c A Reference
       Region 7o5c A 1-70 order
       Region 7o5c A 71-77 disorder
       Region 7o5c A 78-231 order
 Evidence X-RAY 7o5d A Reference
       Region 7o5d A 1-69 order
       Region 7o5d A 70-77 disorder
       Region 7o5d A 78-231 order
 Evidence X-RAY 7o5f A Reference
       Region 7o5f A 1-71 order
       Region 7o5f A 72-77 disorder
       Region 7o5f A 78-231 order
 Evidence X-RAY 7o5g A Reference
       Region 7o5g A 1-70 order
       Region 7o5g A 71-77 disorder
       Region 7o5g A 78-231 order
 Evidence X-RAY 7o5o A Reference
       Region 7o5o A 1-71 order
       Region 7o5o A 72-77 disorder
       Region 7o5o A 78-231 order
 Evidence X-RAY 7o5p A Reference
       Region 7o5p A 1-70 order
       Region 7o5p A 71-77 disorder
       Region 7o5p A 78-231 order
 Evidence X-RAY 7o5s A Reference
       Region 7o5s A 1-70 order
       Region 7o5s A 71-77 disorder
       Region 7o5s A 78-231 order
 Evidence X-RAY 7o5u A Reference
       Region 7o5u A 1-70 order
       Region 7o5u A 71-77 disorder
       Region 7o5u A 78-231 order
 Evidence X-RAY 7o5x A Reference
       Region 7o5x A 1-70 order
       Region 7o5x A 71-77 disorder
       Region 7o5x A 78-231 order
 Evidence X-RAY 7o6f A Reference
       Region 7o6f A 1-69 order
       Region 7o6f A 70-77 disorder
       Region 7o6f A 78-231 order
 Evidence X-RAY 7o6g A Reference
       Region 7o6g A 1-71 order
       Region 7o6g A 72-77 disorder
       Region 7o6g A 78-231 order
 Evidence X-RAY 7o6i A Reference
       Region 7o6i A 1-70 order
       Region 7o6i A 71-77 disorder
       Region 7o6i A 78-231 order
 Evidence X-RAY 7o6j A Reference
       Region 7o6j A 1-69 order
       Region 7o6j A 70-77 disorder
       Region 7o6j A 78-231 order
 Evidence X-RAY 7o6k A Reference
       Region 7o6k A 1-70 order
       Region 7o6k A 71-77 disorder
       Region 7o6k A 78-231 order
 Evidence X-RAY 7o6m A Reference
       Region 7o6m A 1-70 order
       Region 7o6m A 71-77 disorder
       Region 7o6m A 78-231 order
 Evidence X-RAY 7o6o A Reference
       Region 7o6o A 1-70 order
       Region 7o6o A 71-77 disorder
       Region 7o6o A 78-231 order
Seq 1-248 Hetero dimer : IID00654Complex
 Evidence X-RAY 6y1j A Reference
       Region 6y1j A 1-231 order
       Region 6y1j A 232-248 disorder
Seq 1-248 Hetero hexamer : G3XDA1
 Evidence X-RAY 6y7t P Reference
       Region 6y7t P 1-71 order
       Region 6y7t P 72-76 disorder
       Region 6y7t P 77-231 order
       Region 6y7t P 232-248 disorder
 Evidence X-RAY 6y7t K Reference
       Region 6y7t K 1-71 order
       Region 6y7t K 72-76 disorder
       Region 6y7t K 77-231 order
       Region 6y7t K 232-248 disorder
 Evidence X-RAY 6y7t F Reference
       Region 6y7t F 1-70 order
       Region 6y7t F 71-76 disorder
       Region 6y7t F 77-231 order
       Region 6y7t F 232-248 disorder
 Evidence X-RAY 6y7t A Reference
       Region 6y7t A 1-70 order
       Region 6y7t A 71-76 disorder
       Region 6y7t A 77-231 order
       Region 6y7t A 232-248 disorder
Seq 1-248 Hetero dimer : IID00522Complex
 Evidence X-RAY 6y3r A Reference
       Region 6y3r A 1-231 order
       Region 6y3r A 232-248 disorder
 Evidence X-RAY 6zvb A Reference
       Region 6zvb A 1-231 order
       Region 6zvb A 232-248 disorder
 Evidence X-RAY 6zvc A Reference
       Region 6zvc A 1-231 order
       Region 6zvc A 232-248 disorder
 Evidence X-RAY 6zvd A Reference
       Region 6zvd A 1-71 order
       Region 6zvd A 72-73 disorder
       Region 6zvd A 74-231 order
       Region 6zvd A 232-248 disorder
 Evidence X-RAY 6zve A Reference
       Region 6zve A 1-71 order
       Region 6zve A 72-72 disorder
       Region 6zve A 73-76 order
       Region 6zve A 77-77 disorder
       Region 6zve A 78-118 order
       Region 6zve A 119-119 disorder
       Region 6zve A 120-173 order
       Region 6zve A 174-174 disorder
       Region 6zve A 175-180 order
       Region 6zve A 181-181 disorder
       Region 6zve A 182-231 order
       Region 6zve A 232-248 disorder
Seq 1-248 Hetero dimer : IID00207Complex
 Evidence X-RAY 6qhm A Reference
       Region 6qhm A 1-231 order
       Region 6qhm A 232-248 disorder
Seq 1-248 Hetero dimer : Q99466
 Evidence X-RAY 7or3 A Reference
       Region 7or3 A 1-71 order
       Region 7or3 A 72-77 disorder
       Region 7or3 A 78-136 order
       Region 7or3 A 137-138 disorder
       Region 7or3 A 139-231 order
       Region 7or3 A 232-248 disorder
 Evidence X-RAY 7or5 A Reference
       Region 7or5 A 1-71 order
       Region 7or5 A 72-77 disorder
       Region 7or5 A 78-231 order
       Region 7or5 A 232-248 disorder
 Evidence X-RAY 7or7 A Reference
       Region 7or7 A 1-70 order
       Region 7or7 A 71-77 disorder
       Region 7or7 A 78-231 order
       Region 7or7 A 232-248 disorder
Seq 1-248 Hetero dimer : IID00815Complex
 Evidence X-RAY 7obc A Reference
       Region 7obc A 1-231 order
       Region 7obc A 232-248 disorder
 Evidence X-RAY 7obd A Reference
       Region 7obd A 1-231 order
       Region 7obd A 232-248 disorder
 Evidence X-RAY 8b2k A Reference
       Region 8b2k A 1-231 order
 Evidence X-RAY 8bfc A Reference
       Region 8bfc A 1-231 order
Seq 1-248 Hetero dimer : IID00803Complex
 Evidence X-RAY 6y8d A Reference
       Region 6y8d A 1-71 order
       Region 6y8d A 72-73 disorder
       Region 6y8d A 74-231 order
       Region 6y8d A 232-248 disorder
Seqphosphorylation
    248-248 Phosphoserine
    74-74 Phosphoserine
    5-5 Phosphoserine
 
Prediction
NeProc
Disorder 235-248
Order 1-234
ProS 235-240
AlphaFold
Disorder 236-248
Order 1-235
Pfam Hmmer
PF00244 3-238 3e-142
SEG 235-247
Function
Function in SwissProt
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways (PubMed:15731107, PubMed:22634725, PubMed:28202711, PubMed:37797010). Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif (PubMed:15731107, PubMed:22634725, PubMed:28202711, PubMed:37797010). Binding generally results in the modulation of the activity of the binding partner (PubMed:15731107, PubMed:22634725, PubMed:28202711, PubMed:37797010). Promotes cytosolic retention of GBP1 GTPase by binding to phosphorylated GBP1, thereby inhibiting the innate immune response (PubMed:37797010). Also acts as a TP53/p53-regulated inhibitor of G2/M progression (PubMed:9659898). When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway (By similarity). May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53 (PubMed:18382127).
Biological Process
See also
Diagram with PDB data
ESR1/SFN14-3-3 protein interaction with Estrogen Receptor Alpha provides a novel drug target interface
RAF1/YWHAZHuman 14-3-3 isoform zeta in complex with a diphoyphorylated C-RAF peptide and Cotylenin A
TP53/SFNCrystal structure of 14-3-3sigma and a p53 C-terminal 12-mer synthetic phosphopeptide
YAP1/SFN14-3-3 sigma in complex with YAP pS127-peptide
FOXO1/SFN14-3-3 sigma in complex with FOXO1 pT24 peptide
AMOT/SFNCrystal structure of 14-3-3 sigma in complex with 20mer Amot-p130 peptide
WWTR1/SFN14-3-3 sigma in complex with TAZ pS89 peptide
GAB2/GRB2Grb2 SH3C (3)
Diagram without PDB data
CDKN1BActivation of Akt results in phosphorylation p27, which are then transported to the cytoplasm with 14-3-3.
FOXO4Stress signals in FOXO regulation