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IID00368
 UniprotP28702
ProteinRetinoic acid receptor RXR-beta
GeneRXRB
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
533
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 293-528 Hetero dimer : IID00082Complex,IID00373Complex
 Evidence X-RAY 5i4v F Reference
       Region 5i4v F 293-296 disorder
       Region 5i4v F 297-312 order
       Region 5i4v F 313-334 disorder
       Region 5i4v F 335-514 order
       Region 5i4v F 515-518 disorder
       Region 5i4v F 519-528 order
Seq 293-528 Hetero dimer : IID00082Complex,IID00373Complex
 Evidence X-RAY 5i4v B Reference
       Region 5i4v B 293-296 disorder
       Region 5i4v B 297-312 order
       Region 5i4v B 313-334 disorder
       Region 5i4v B 335-513 order
       Region 5i4v B 514-516 disorder
       Region 5i4v B 517-528 order
Seq 293-533 Hetero dimer : IID00373Complex
 Evidence X-RAY 5kyj F Reference
       Region 5kyj F 293-296 disorder
       Region 5kyj F 297-312 order
       Region 5kyj F 313-333 disorder
       Region 5kyj F 334-514 order
       Region 5kyj F 515-518 disorder
       Region 5kyj F 519-528 order
 Evidence X-RAY 5kyj B Reference
       Region 5kyj B 293-296 disorder
       Region 5kyj B 297-312 order
       Region 5kyj B 313-333 disorder
       Region 5kyj B 334-513 order
       Region 5kyj B 514-516 disorder
       Region 5kyj B 517-528 order
 Evidence X-RAY 5kya F Reference
       Region 5kya F 293-296 disorder
       Region 5kya F 297-312 order
       Region 5kya F 313-334 disorder
       Region 5kya F 335-514 order
       Region 5kya F 515-518 disorder
       Region 5kya F 519-528 order
 Evidence X-RAY 5kya B Reference
       Region 5kya B 293-296 disorder
       Region 5kya B 297-312 order
       Region 5kya B 313-334 disorder
       Region 5kya B 335-514 order
       Region 5kya B 515-518 disorder
       Region 5kya B 519-528 order
 Evidence X-RAY 5hjp C Reference
       Region 5hjp C 299-312 order
       Region 5hjp C 313-334 disorder
       Region 5hjp C 335-528 order
       Region 5hjp C 529-533 disorder
 Evidence X-RAY 5hjp A Reference
       Region 5hjp A 299-312 order
       Region 5hjp A 313-335 disorder
       Region 5hjp A 336-528 order
       Region 5hjp A 529-533 disorder
Seq 298-533 Hetero tetramer : IID00082Complex,IID00243Complex
 Evidence X-RAY 1uhl A Reference
       Region 1uhl A 298-313 order
       Region 1uhl A 314-330 disorder
       Region 1uhl A 331-528 order
       Region 1uhl A 529-533 disorder
Seq 299-522 Homo octamer :
 Evidence X-RAY 1h9u D Reference
       Region 1h9u D 299-311 order
       Region 1h9u D 312-334 disorder
       Region 1h9u D 335-522 order
 Evidence X-RAY 1h9u C Reference
       Region 1h9u C 299-311 order
       Region 1h9u C 312-334 disorder
       Region 1h9u C 335-522 order
 Evidence X-RAY 1h9u B Reference
       Region 1h9u B 299-311 order
       Region 1h9u B 312-334 disorder
       Region 1h9u B 335-522 order
 Evidence X-RAY 1h9u A Reference
       Region 1h9u A 299-311 order
       Region 1h9u A 312-334 disorder
       Region 1h9u A 335-522 order
 
Prediction
NeProc
Disorder 1-201,274-331,529-533
Order 202-273,332-528
ProS 1-45,57-65,71-76,131-138,274-281,301-316,323-326,529-533
AlphaFold
Disorder 1-96,98-102,104-202,280-297,314-333,515-516,528-533
Order 97-97,103-103,203-279,298-313,334-514,517-527
Pfam Hmmer
PF00105 203-278 2.7e-53
PF00104 344-525 3.2e-68
SEG 46-134 ,137-160 ,192-199 ,251-265 ,282-298 ,321-332
Function
Function in SwissProt
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE).