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IID00457  Histone deacetylase 4 (Homo sapiens) P56524
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
1084
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 62-153 Homo tetramer :
 Evidence X-RAY 2h8n A Reference
       Region 2h8n A 62-129 order
       Region 2h8n A 130-153 disorder
 Evidence X-RAY 2h8n B Reference
       Region 2h8n B 62-129 order
       Region 2h8n B 130-153 disorder
 Evidence X-RAY 2h8n C Reference
       Region 2h8n C 62-129 order
       Region 2h8n C 130-153 disorder
 Evidence X-RAY 2h8n D Reference
       Region 2h8n D 62-129 order
       Region 2h8n D 130-153 disorder
 Evidence X-RAY 2o94 A Reference
       Region 2o94 A 62-129 order
       Region 2o94 A 130-153 disorder
 Evidence X-RAY 2o94 B Reference
       Region 2o94 B 62-129 order
       Region 2o94 B 130-153 disorder
 Evidence X-RAY 2o94 C Reference
       Region 2o94 C 62-129 order
       Region 2o94 C 130-153 disorder
 Evidence X-RAY 2o94 D Reference
       Region 2o94 D 62-129 order
       Region 2o94 D 130-153 disorder
Seq 343-359 Hetero dimer : Q9H9E1
 Evidence X-RAY 3v31 B Reference
       Region 3v31 B 343-359 order
Seq 343-359 Hetero dimer : P61981
 Evidence X-RAY 3uzd B Reference
       Region 3uzd B 343-347 disorder
       Region 3uzd B 348-356 order
       Region 3uzd B 357-359 disorder
Seq 343-359 Hetero dimer : IID00427Complex
 Evidence X-RAY 3uxg B Reference
       Region 3uxg B 343-343 disorder
       Region 3uxg B 344-359 order
Seq 648-1057 Monomer :
 Evidence X-RAY 5a2s A Reference
       Region 5a2s A 648-652 disorder
       Region 5a2s A 653-1032 order
       Region 5a2s A 1033-1033 disorder
 Evidence X-RAY 5a2s B Reference
       Region 5a2s B 648-652 disorder
       Region 5a2s B 653-1032 order
       Region 5a2s B 1033-1033 disorder
 Evidence X-RAY 4cbt A Reference
       Region 4cbt A 648-649 disorder
       Region 4cbt A 650-728 order
       Region 4cbt A 729-757 disorder
       Region 4cbt A 758-997 order
       Region 4cbt A 998-1004 disorder
       Region 4cbt A 1005-1033 order
 Evidence X-RAY 4cbt B Reference
       Region 4cbt B 648-648 disorder
       Region 4cbt B 649-727 order
       Region 4cbt B 728-757 disorder
       Region 4cbt B 758-995 order
       Region 4cbt B 996-997 disorder
       Region 4cbt B 998-1032 order
       Region 4cbt B 1033-1033 disorder
 Evidence X-RAY 4cbt C Reference
       Region 4cbt C 648-669 order
       Region 4cbt C 670-673 disorder
       Region 4cbt C 674-728 order
       Region 4cbt C 729-759 disorder
       Region 4cbt C 760-829 order
       Region 4cbt C 830-831 disorder
       Region 4cbt C 832-996 order
       Region 4cbt C 997-1002 disorder
       Region 4cbt C 1003-1033 order
 Evidence X-RAY 4cby A Reference
       Region 4cby A 648-652 disorder
       Region 4cby A 653-1032 order
       Region 4cby A 1033-1033 disorder
 Evidence X-RAY 4cby B Reference
       Region 4cby B 648-651 disorder
       Region 4cby B 652-1031 order
       Region 4cby B 1032-1033 disorder
 Evidence X-RAY 4cby C Reference
       Region 4cby C 648-652 disorder
       Region 4cby C 653-1032 order
       Region 4cby C 1033-1033 disorder
 Evidence X-RAY 4cby D Reference
       Region 4cby D 648-652 disorder
       Region 4cby D 653-1033 order
 Evidence X-RAY 2vqj A Reference
       Region 2vqj A 648-649 disorder
       Region 2vqj A 650-1051 order
       Region 2vqj A 1052-1057 disorder
 Evidence X-RAY 2vqm A Reference
       Region 2vqm A 648-649 disorder
       Region 2vqm A 650-670 order
       Region 2vqm A 671-677 disorder
       Region 2vqm A 678-731 order
       Region 2vqm A 732-735 disorder
       Region 2vqm A 736-1051 order
       Region 2vqm A 1052-1057 disorder
 Evidence X-RAY 2vqq A Reference
       Region 2vqq A 648-650 disorder
       Region 2vqq A 651-666 order
       Region 2vqq A 667-677 disorder
       Region 2vqq A 678-728 order
       Region 2vqq A 729-755 disorder
       Region 2vqq A 756-1049 order
       Region 2vqq A 1050-1057 disorder
 Evidence X-RAY 2vqq B Reference
       Region 2vqq B 648-650 disorder
       Region 2vqq B 651-665 order
       Region 2vqq B 666-679 disorder
       Region 2vqq B 680-728 order
       Region 2vqq B 729-756 disorder
       Region 2vqq B 757-1049 order
       Region 2vqq B 1050-1057 disorder
 Evidence X-RAY 2vqv A Reference
       Region 2vqv A 648-650 disorder
       Region 2vqv A 651-664 order
       Region 2vqv A 665-678 disorder
       Region 2vqv A 679-727 order
       Region 2vqv A 728-758 disorder
       Region 2vqv A 759-1049 order
       Region 2vqv A 1050-1057 disorder
 Evidence X-RAY 2vqv B Reference
       Region 2vqv B 648-650 disorder
       Region 2vqv B 651-664 order
       Region 2vqv B 665-677 disorder
       Region 2vqv B 678-728 order
       Region 2vqv B 729-758 disorder
       Region 2vqv B 759-1049 order
       Region 2vqv B 1050-1057 disorder
 Evidence X-RAY 2vqw G Reference
       Region 2vqw G 648-650 disorder
       Region 2vqw G 651-669 order
       Region 2vqw G 670-672 disorder
       Region 2vqw G 673-728 order
       Region 2vqw G 729-743 disorder
       Region 2vqw G 744-1050 order
       Region 2vqw G 1051-1057 disorder
Seq 648-1057 Homo dimer :
 Evidence X-RAY 2vqo A Reference
       Region 2vqo A 648-650 disorder
       Region 2vqo A 651-666 order
       Region 2vqo A 667-678 disorder
       Region 2vqo A 679-728 order
       Region 2vqo A 729-755 disorder
       Region 2vqo A 756-1049 order
       Region 2vqo A 1050-1057 disorder
 Evidence X-RAY 2vqo B Reference
       Region 2vqo B 648-650 disorder
       Region 2vqo B 651-665 order
       Region 2vqo B 666-678 disorder
       Region 2vqo B 679-728 order
       Region 2vqo B 729-756 disorder
       Region 2vqo B 757-1049 order
       Region 2vqo B 1050-1057 disorder
Seqphosphorylation
    210-210 Phosphoserine
    246-246 Phosphoserine; by CaMK4 and SIK1
    350-350 Phosphoserine
    467-467 Phosphoserine; by CaMK4 and SIK1
    565-565 Phosphoserine
    632-632 Phosphoserine; by CaMK4
    633-633 Phosphoserine
 
Prediction
DICHOT
Disorder 1-649,1052-1084
Known Domain 650-1051
SCOPe RPS-Blast
     1f5nA1 49-158 3e-08 a.114.1.1 Interferon-induced guanylate-binding p...
     5wgiA1 653-1032 e-153 c.42.1.0 automated matches
SCOP Hmmer
     3c10A1 651-1032 5.6e-121 Arginase/deacetylase
Pfam RPS-Blast
     PF12203 114-152 2e-04 Glutamine rich N terminal d...
     PF00850 925-988 6e-05 Histone deacetylase domain
Pfam Hmmer
    PF12203 63-152 1.5e-40 Glutamine rich N terminal d...
    PF00850 675-992 6.7e-86 Histone deacetylase domain