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IID00461  Heat shock factor protein 1 (Homo sapiens) Q00613
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
xml
Experiment
529
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-120 Homo dimer :
 Evidence X-RAY 5d5v B Reference
       Region 5d5v B 1-13 disorder
       Region 5d5v B 14-83 order
       Region 5d5v B 84-94 disorder
       Region 5d5v B 95-120 order
 Evidence X-RAY 5d5v D Reference
       Region 5d5v D 1-12 disorder
       Region 5d5v D 13-88 order
       Region 5d5v D 89-89 disorder
       Region 5d5v D 90-120 order
Seq 1-120 Homo dimer :
 Evidence X-RAY 5d5u B Reference
       Region 5d5u B 1-12 disorder
       Region 5d5u B 13-85 order
       Region 5d5u B 86-92 disorder
       Region 5d5u B 93-119 order
       Region 5d5u B 120-120 disorder
 Evidence X-RAY 5hdn A Reference
       Region 5hdn A 15-85 order
       Region 5hdn A 86-89 disorder
       Region 5hdn A 90-118 order
       Region 5hdn A 119-120 disorder
 Evidence X-RAY 5hdn B Reference
       Region 5hdn B 15-86 order
       Region 5hdn B 87-93 disorder
       Region 5hdn B 94-118 order
       Region 5hdn B 119-120 disorder
 Evidence X-RAY 5hdn C Reference
       Region 5hdn C 15-118 order
       Region 5hdn C 119-120 disorder
 Evidence X-RAY 5hdn D Reference
       Region 5hdn D 15-84 order
       Region 5hdn D 85-95 disorder
       Region 5hdn D 96-118 order
       Region 5hdn D 119-120 disorder
Seq 10-123 Monomer :
 Evidence X-RAY 5hdg A Reference
       Region 5hdg A 15-85 order
       Region 5hdg A 86-95 disorder
       Region 5hdg A 96-117 order
       Region 5hdg A 118-120 disorder
 Evidence NMR 2ldu A Reference
       Region 2ldu A 10-123 order
       Region 2ldu A 10-12 high_rmsd
       Region 2ldu A 88-88 high_rmsd
       Region 2ldu A 119-123 high_rmsd
Seqdisorder 208-379,412-529
 Evidence CD Reference
       Region 208-379 disorder
       Region 412-529 disorder
Seqphosphorylation
    121-121 Phosphoserine; by MAPKAPK2
    142-142 Phosphothreonine; by CK2
    216-216 Phosphoserine; by PLK1
    230-230 Phosphoserine; by CAMK2A
    275-275 Phosphoserine
    292-292 Phosphoserine
    303-303 Phosphoserine; by GSK3-beta
    307-307 Phosphoserine; by MAPK3
    314-314 Phosphoserine
    319-319 Phosphoserine
    320-320 Phosphoserine; by PKA
    323-323 Phosphothreonine
    326-326 Phosphoserine; by MAPK12
    344-344 Phosphoserine
    363-363 Phosphoserine; by MAPK8
    419-419 Phosphoserine; by PLK1
    444-444 Phosphoserine
Seqacetylation
    1-1 N-acetylmethionine
    80-80 N6-acetyllysine
    91-91 N6-acetyllysine; alternate
    118-118 N6-acetyllysine
    150-150 N6-acetyllysine
    188-188 N6-acetyllysine
    208-208 N6-acetyllysine; alternate
    298-298 N6-acetyllysine; alternate
    524-524 N6-acetyllysine
 
Prediction
DICHOT
Disorder 1-9,124-141,174-529
Known Domain 10-123
Cryptic Domain 142-173
SCOPe RPS-Blast
     5hdkA1 15-118 1e-56 a.4.5.0 automated matches
SCOP Hmmer
     1hksA_ 13-118 9.9e-45 a.4.5.22 Heat-shock trans...
Pfam RPS-Blast
     PF00447 18-118 7e-20 HSF-type DNA-binding
     PF06546 247-529 7e-49 Vertebrate heat shock trans...
Pfam Hmmer
    PF00447 18-118 7.2e-37 HSF-type DNA-binding
    PF06546 247-529 3.9e-131 Vertebrate heat shock tra...